Patents by Inventor Toshihiko Toida

Toshihiko Toida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING HEPARIN-LIKE SUBSTANCE, RECOMBINANT CELL, AND METHOD FOR PRODUCING THE SAME
    Publication number: 20220380489
    Abstract: An object of the present invention is to provide a method for efficiently producing a heparin-like substance without using an animal-derived tissue. The present invention relates to a method for producing a heparin-like substance and the like, the method comprising: (1) preparing a mammalian cell that produces a heparin-like substance, (2) preparing a recombinant cell in which a gene that encodes an extracellular domain of syndecan is introduced into the mammalian cell that produces a heparin-like substance and is prepared in step (1), and (3) culturing the recombinant cell prepared in step (2) in a medium and collecting the heparin-like substance from the resulting culture supernatant.
    Type: Application
    Filed: October 2, 2020
    Publication date: December 1, 2022
    Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY, KYOWA HAKKO BIO CO., LTD.
    Inventors: Masamichi KAMIHIRA, Yoshinori KAWABE, Kosuke SAGAWA, Toshihiko TOIDA, Satoshi KOIZUMI
  • Method for producing alkyl-esterified glycosaminoglycan
    Publication number: 20060172967
    Abstract: A method for producing an alkyl-esterified glycosaminoglycan, which comprises the step of allowing a trialkylsilyldiazoalkane to act on a glycosaminoglycan to perform alkyl-esterification of carboxyl groups of the glycosaminoglycan, and an alkyl-esterified glycosaminoglycan having a property that it is not substantially degraded by a glycosaminoglycan degrading enzyme such as hyaluronidase are provided.
    Type: Application
    Filed: October 5, 2005
    Publication date: August 3, 2006
    Applicant: Seikagaku Corporation
    Inventor: Toshihiko Toida