Patents by Inventor Toshihiko Wada

Toshihiko Wada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4801334
    Abstract: A magnetic recording disk accommodated in a casing is rotated and air in the casing is drawn through air sucking openings formed in the upper and lower sides of the casing.
    Type: Grant
    Filed: May 19, 1987
    Date of Patent: January 31, 1989
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Toshihiko Wada, Hideki Matsuzawa
  • Patent number: 4699787
    Abstract: A method of restoring the immune response of a patient having a lowered immune response level is provided, in which the patient is given an effective amount of certain nitrogen-containing polysaccharides derived from Coriolus versicolor (Fr.) Quel, where the polymer units having a molecular weight of below about 5,000 have been removed therefrom.
    Type: Grant
    Filed: March 6, 1984
    Date of Patent: October 13, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Saburo Ueno, Chikao Yoshikumi, Yoshio Omura, Takayoshi Fujii, Toshihiko Wada, Eiichi Takahashi, Fumio Hirose
  • Patent number: 4472907
    Abstract: A fruit body of Ganoderma lucidum (Fr.) Karst. having a long stipe is prepared by the method of the invention comprising the following steps;(a) cultivating a seed culture of a Ganoderma lucidum (Fr.) Karst. strain in an artificial solid medium to obtain a fungal tissue bed,(b) maintaining the fungal tissue bed at a humidity of at least 90% and an illumination intensity of at most 500 l.times. to form selectively a primordium of fruit body from the fungal tissue bed, and(c) maintaining the resulting culture at a humidity of from 40 to lower than 90% and an illumination intensity of at least 500 l.times. to form a fungal pileus of the fruit body from the primordium.
    Type: Grant
    Filed: September 24, 1982
    Date of Patent: September 25, 1984
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Toshihiko Wada, Akiyoshi Nakashima, Azuma Okubo, Yoshio Ohmura, Chikao Yoshikumi
  • Patent number: 4369253
    Abstract: Disclosed is a method for producing the high-quality mycelia of the Basidiomycetes from culture thereof by promoting growth of the fungus as well as differentiation of the cells and attendant organization thereof by adding to the culture medium a straight chain saturated aliphatic alcohol with a catbon number within a specified range of 26 to 36 carbon atoms.
    Type: Grant
    Filed: March 24, 1981
    Date of Patent: January 18, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Takita, Toshihiko Wada, Yutaka Mukaida, Satoru Enomoto, Akiyoshi Nakajima, Azuma Okubo
  • Patent number: 4288555
    Abstract: In submerged culture of a Basidiomycete belonging to the genus Coriolus, the seed culture to be inoculated into the medium is homogenized to form a homogenous slurry and the slurry-formed seed culture is inoculated into the medium. This improves the cultivation rate of the Basidiomycetes.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: September 8, 1981
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Toshihiko Wada, Himromitsu Makita, Kinzaburo Suzuki
  • Patent number: 4237233
    Abstract: In cultivation of the Basidiomycetes under aeration and agitation in an aqueous liquid medium containing saccharide as a carbon source and yeast extract, peptone, casamino acid and/or meat extract as nutrient, the initial charge of the medium is adjusted such that it is less than about 70% of the capacity of the fermentor used, and the medium or at least one component thereof is supplied additionally in portions as cultivation advances. Such control of the medium feed suppresses excessive foaming which occurs in the aqueous medium during cultivation, and allows smooth and efficient cultivation of the Basidiomycetes.
    Type: Grant
    Filed: July 26, 1977
    Date of Patent: December 2, 1980
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Toshihiko Wada, Hiromitsu Makita, Kinzaburo Suzuki, Azuma Okubo, Takishi Nakanoya, Katsunori Miura, Tadao Sagi
  • Patent number: 4229570
    Abstract: The fungi belonging to the Coriolus genus is first extracted with water or a dilute alkaline solution and then further extracted stepwise by using alkaline solutions with gradually increased concentrations to obtain a nitrogen-containing polysaccharide having an anti-tumor activity in a high yield.
    Type: Grant
    Filed: April 19, 1977
    Date of Patent: October 21, 1980
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Saburo Ueno, Chikao Yoshikumi, Fumio Hirose, Yoshio Omura, Toshihiko Wada, Takayoshi Fujii, Eiichi Takahashi
  • Patent number: 4202969
    Abstract: The fungi belonging to the Coriolus genus are extracted by using a dilute alkaline solution having a concentration within a certain specified range whereby the low molecular weight substances with molecular weight of less than 5,000 are obtained in there extract solution. These low molecular weight substances are separated from the extract solution to obtain a nitrogen-containing polysaccharide having excellent anti-tumor activity.
    Type: Grant
    Filed: April 19, 1977
    Date of Patent: May 13, 1980
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Saburo Ueno, Chikao Yoshikumi, Fumio Hirose, Yoshio Omura, Toshihiko Wada, Takayoshi Fujii, Eiichi Takahashi
  • Patent number: 4159225
    Abstract: When a dikaryotic mycelium of Coriolus versicolor (Fr.) Quel. (a species of fungi belonging to the genus Coriolus of Polyporaceae) is subjected to a mechanical treatment such as grinding or shearing in a liquid medium, or when such mycelium is subjected to submerged culture while undergoing mechanical treatment, there is produced a monokaryotic mycelium which is different from the dikaryotic mycelium in morphological and physiological characteristics. The thus obtained monokaryotic mycelium is a novel product and characterized by its extremely high propagation rate as compared with the known dikaryotic mycelium. Also, the substance extracted from the culture of the mycelium has excellent physiological activities.
    Type: Grant
    Filed: August 19, 1977
    Date of Patent: June 26, 1979
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Omura, Toshihiko Wada, Hiromitsu Makita, Takao Ando, Noriyuki Toyoda, Kenichi Matsunaga
  • Patent number: 4140578
    Abstract: A fungus belonging to genus Coriolus of the class Basidiomycetes is subjected to submerged culture in a liquid medium and the obtained culture is dried and extracted with an aqueous solvent, and then the substances with molecular weights of less than 5,000 are eliminated from the extract solution, whereby a polysaccharide having anti-cancer and other pharmacodynamic effects is obtained in a high yield.
    Type: Grant
    Filed: July 20, 1977
    Date of Patent: February 20, 1979
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Toshihiko Wada, Masahiko Fujii, Hiromitsu Makita, Kinzaburo Suzuki, Akio Shinmyo, Haruhisa Hayashi
  • Patent number: 4051314
    Abstract: Polysaccharides are produced by purifying a liquid extract of a mycelium of a strain of fungus species belonging to the class Basidiomycetes or the filtered broth of a cultured medium in which a mycelium of a selected strain of Basidiomycetes has been incubated; the polysaccharides exhibiting an anticarcinogenic activity in mice.
    Type: Grant
    Filed: October 11, 1974
    Date of Patent: September 27, 1977
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Shigeto Ohtsuka, Saburo Ueno, Chikao Yoshikumi, Fumio Hirose, Yoshio Ohmura, Toshihiko Wada, Takayoshi Fujii, Eiichi Takahashi