Patents by Inventor Toshihiko Yamashita
Toshihiko Yamashita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240122988Abstract: The present invention relates to a synapse formation promoter and a brain plasticity promoter comprising CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow aspirate and treatment of dementia, chronic-phase cerebral infarction, chronic-phase spinal cord injury, mental diseases, and the like using the synapse formation promoter and brain plasticity promoter.Type: ApplicationFiled: April 26, 2023Publication date: April 18, 2024Applicants: Sapporo Medical University, Nipro CorporationInventors: Osamu Honmou, Masanori Sasaki, Rie Maezawa, Shinichi Oka, Yuko Sasaki, Masahito Nakazaki, Toshihiko Yamashita
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Patent number: 11926883Abstract: Provided is a method which allows for strict control of an oxygen partial pressure required for the heating and melting of a raw material, and thereby more efficient recovery of a valuable metal. The method for recovering a valuable metal (Cu, Ni, and Co) includes the steps of: preparing a charge comprising at least phosphorus (P) and a valuable metal as a raw material; heating and melting the raw material to form a molten body and then converting the molten body into a molten product comprising an alloy and a slag; and separating the slag from the molten product to recover the alloy comprising the valuable metal, wherein the heating and melting of the raw material comprises directly measuring an oxygen partial pressure in the molten body using an oxygen analyzer, and regulating the oxygen partial pressure based on the obtained measurement result.Type: GrantFiled: June 29, 2021Date of Patent: March 12, 2024Assignee: SUMITOMO METAL MINING CO., LTD.Inventors: Yu Yamashita, Toshihiko Nagakura, Tomoya Hagio
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Patent number: 11666601Abstract: The present invention relates to a synapse formation promoter and a brain plasticity promoter comprising CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow aspirate and treatment of dementia, chronic-phase cerebral infarction, chronic-phase spinal cord injury, mental diseases, and the like using the synapse formation promoter and brain plasticity promoter.Type: GrantFiled: April 26, 2017Date of Patent: June 6, 2023Assignees: Sapporo Medical University, Nipro CorporationInventors: Osamu Honmou, Masanori Sasaki, Rie Maezawa, Shinichi Oka, Yuko Sasaki, Masahito Nakazaki, Toshihiko Yamashita
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Publication number: 20190117700Abstract: The present invention relates to a synapse formation promoter and a brain plasticity promoter comprising CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow aspirate and treatment of dementia, chronic-phase cerebral infarction, chronic-phase spinal cord injury, mental diseases, and the like using the synapse formation promoter and brain plasticity promoter.Type: ApplicationFiled: April 26, 2017Publication date: April 25, 2019Applicants: Sapporo Medical University, Nipro CorporationInventors: Osamu Honmou, Masanori SASAKI, Rie MAEZAWA, Shinichi OKA, Yuko SASAKI, Masahito NAKAZAKI, Toshihiko YAMASHITA
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Publication number: 20100255579Abstract: An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.Type: ApplicationFiled: February 8, 2010Publication date: October 7, 2010Applicants: Dainippon Sumitomo Pharma Co., Ltd., Noriyuki SATOInventors: Noriyuki SATO, Tomohide Tsukahara, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Takuro Wada, Toshihiko Yamashita
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Patent number: 7700108Abstract: An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.Type: GrantFiled: September 19, 2003Date of Patent: April 20, 2010Assignees: Dainippon Sumitomo Pharma Co., Ltd.Inventors: Noriyuki Sato, Tomohide Tsukahara, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Takuro Wada, Toshihiko Yamashita
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Publication number: 20080014636Abstract: An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.Type: ApplicationFiled: September 19, 2003Publication date: January 17, 2008Inventors: Noriyuki Sato, Tomohide Tsukahara, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Takuro Wada, Toshihiko Yamashita
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Patent number: 7069774Abstract: A crank angle detecting device that is independent of fluctuations in engine rotational speed and reliably detects a reference crank angle position. A ring gear fixed to a crankshaft of a single cylinder engine has plural projections (teeth) formed around its outer periphery at equal intervals and one irregular interval portion (toothless portion). A crank angle sensor detects start and end on both sides of each projection, a lateral length of each projection and an interval of two adjacent projections, and calculates a ratio therebetween to distinguish the irregular interval portion from the projections. The crank angle sensor and the irregular interval portion are so positioned that the irregular interval portion is detected when the piston is close to bottom dead center.Type: GrantFiled: October 8, 2002Date of Patent: July 4, 2006Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Tomoji Nakamura, Toshihiko Yamashita
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Patent number: 6994902Abstract: A metallic porous body includes a number of protrusions formed on obverse and reverse sides of a metal sheet so as to protrude alternately with one another; each of the protrusions being formed into an truncated-shape wherein an opening portion punched out in the direction from the upper-side bottom to the lower-side bottom is formed in the upper-side bottom of each protrusion, and a vertical distance (d) between the upper-side bottom on the obverse side and the upper-side bottom on the reverse side, and a height (e) of a punched portion have a relation: 0.3<e/d<0.9, thereby attaining a metallic porous body without a burr or a edged convex portion on its outside surface, with a large number of fine pores arranged at fine pitch and a light-weight and robust skeleton.Type: GrantFiled: December 17, 2003Date of Patent: February 7, 2006Assignees: Hitachi Maxell, Ltd., Kushibe Manufacturing Co., Ltd.Inventors: Hiroshi Fukunaga, Mitsuhiro Kishimi, Masao Morishima, Toshihiko Yamashita
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Patent number: 6978768Abstract: To provide an acceleration control method for an engine, which determines the accelerating state appropriately without a sensor, a mechanism, or the like specially added for determining the accelerating state and performs suitable acceleration control, while it prevents acceleration misdetermination at engine start or at an extremely low engine speed to improve engine startability and drivability at an extremely low engine speed.Type: GrantFiled: October 8, 2002Date of Patent: December 27, 2005Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Toshihiko Yamashita, Tomoji Nakamura
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Patent number: 6968269Abstract: To detect a stroke reliably at the time of the start of the engine when a stroke cannot be detected based on crank pulses alone. A stroke is detected based on a difference ?N between the engine rotational speeds at top and bottom dead centers and a flag FN is changed depending upon whether a temporary stroke set before a stroke has been detected and the detected stroke coincide with each other or not. Simultaneously, a stroke is detected based on a difference ?P between the intake air pressures at two bottom dead centers and a flag Fp is changed depending upon whether a temporary stroke set before a stroke has been detected and the detected stroke coincide with each other or not. Then, when the flags FN and Fp coincide with each other, the stroke detection is completed. When the detected stroke differs from the temporary stroke, the stroke is shifted by a phase of 360° and the crank pulses are renumbered.Type: GrantFiled: April 11, 2003Date of Patent: November 22, 2005Assignee: Yamaha Hatsudoki Kabushiki KaishaInventor: Toshihiko Yamashita
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Publication number: 20050205057Abstract: To detect a stroke reliably at the time of the start of the engine when a stroke cannot be detected based on crank pulses alone. A stroke is detected based on a difference ?N between the engine rotational speeds at top and bottom dead centers and a flag FN is changed depending upon whether a temporary stroke set before a stroke has been detected and the detected stroke coincide with each other or not. Simultaneously, a stroke is detected based on a difference ?P between the intake air pressures at two bottom dead centers and a flag FP is changed depending upon whether a temporary stroke set before a stroke has been detected and the detected stroke coincide with each other or not. Then, when the flags FN and FP coincide with each other, the stroke detection is completed. When the detected stroke differs from the temporary stroke, the stroke is shifted by a phase of 360° and the crank pulses are renumbered.Type: ApplicationFiled: April 11, 2003Publication date: September 22, 2005Inventor: Toshihiko Yamashita
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Patent number: 6830038Abstract: To provide a fuel cutoff control method for an engine including a secondary air introducing system, capable of preventing afterburning in an exhaust pipe at the time of fuel being cut off in a decelerating state of the engine. A fuel cutoff control method during deceleration of an engine including a secondary air introducing pipe connected to an exhaust pipe, and an air cut valve provided on the secondary air introducing pipe, the method comprising a determination step of determining under predetermined condition's whether or not the engine is in a decelerating state, wherein in the decelerating state, a greater amount of fuel than a normally required amount of fuel flow is supplied during a predetermined period of time after the start of deceleration, and then fuel is cut off after the predetermined period of time has elapsed.Type: GrantFiled: April 30, 2004Date of Patent: December 14, 2004Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Toshihiko Yamashita, Tomoji Nakamura
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Publication number: 20040187843Abstract: To provide a fuel cutoff control method for an engine including a secondary air introducing system, capable of preventing afterburning in an exhaust pipe at the time of fuel being cut off in a decelerating state of the engine.Type: ApplicationFiled: April 30, 2004Publication date: September 30, 2004Inventors: Toshihiko Yamashita, Tomoji Nakamura
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Publication number: 20040182142Abstract: To provide a crank angle detecting device for an engine independent of fluctuations in engine rotational speed while performing more reliable detection of a reference crank angle position.Type: ApplicationFiled: April 30, 2004Publication date: September 23, 2004Inventors: Tomoji Nakamura, Toshihiko Yamashita
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Publication number: 20040168676Abstract: To provide an acceleration control method for an engine, which determines the accelerating state appropriately without a sensor, a mechanism, or the like specially added for determining the accelerating state and performs suitable acceleration control, while it prevents acceleration misdetermination at engine start or at an extremely low engine speed to improve engine startability and drivability at an extremely low engine speed.Type: ApplicationFiled: April 19, 2004Publication date: September 2, 2004Inventors: Toshihiko Yamashita, Tomoji Nakamura
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Publication number: 20040142201Abstract: A metallic porous body includes a number of protrusions formed on obverse and reverse sides of a metal sheet so as to protrude alternately with one another; each of the protrusions being formed into an truncated-shape wherein an opening portion punched out in the direction from the upper-side bottom to the lower-side bottom is formed in the upper-side bottom of each protrusion, and a vertical distance (d) between the upper-side bottom on the obverse side and the upper-side bottom on the reverse side, and a height (e) of a punched portion have a relation: 0.3<e/d<0.9, thereby attaining a metallic porous body without a burr or a edged convex portion on its outside surface, with a large number of fine pores arranged at fine pitch and a light-weight and robust skeleton.Type: ApplicationFiled: December 17, 2003Publication date: July 22, 2004Inventors: Hiroshi Fukunaga, Mitsuhiro Kishimi, Masao Morishima, Toshihiko Yamashita
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Patent number: 6420821Abstract: A cathode for a magnetron having concave/convex portions on a surface of a cylindrical base metal with thermionic emitting materials being fixedly attached to concave portions from among the concave/convex portions. The convex portions of the concave/convex portions are arranged to be inclining. It is enabled to effectively protect thermionic emitting materials from inverse impulse of electrons or ions and from oscillation to thereby restrain consumption and omission of these thermionic emitting materials and to decrease higher harmonics of radiation.Type: GrantFiled: January 21, 2000Date of Patent: July 16, 2002Assignee: New Japan Radio Co., LTDInventors: Kiyoshi Kishiki, Yukio Torikai, Toshihiko Yamashita, Hideyuki Obata
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Patent number: 5313518Abstract: A method of unlocking a compartment such as a drawer in a desk where a telephone is provided on the desk, the telephone being of the type where a series of frequency tones are generated for dialing a number. The user places the handset of the telephone near a microphone receiver and dials a preset sequence of numbers on the telephone. The sound output from the handset is received by the microphone receiver, decoded and compared in memory with a preset code and if valid the lock is released to allow the drawer to be opened.Type: GrantFiled: November 4, 1991Date of Patent: May 17, 1994Inventor: Toshihiko Yamashita
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Patent number: D507778Type: GrantFiled: June 25, 2004Date of Patent: July 26, 2005Assignees: Hitachi Maxell Ltd., Kushibe Manufacturing Co., Ltd.Inventors: Hiroshi Fukunaga, Mitsuhiro Kishimi, Masao Morishima, Toshihiko Yamashita