Patents by Inventor Toshihiro Hamajima

Toshihiro Hamajima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS
    Publication number: 20100016307
    Abstract: The present invention relates to compounds of formula (I): and processes for preparing them, compositions containing them and their use in treating diseases relating to inappropriate c-Met activity.
    Type: Application
    Filed: October 24, 2007
    Publication date: January 21, 2010
    Inventors: Toshihiro Hamajima, Hiroko Nakamura, Jun Tang
  • Azaindole inhibitors of aurora kinases
    Patent number: 7495102
    Abstract: The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: February 24, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Martha A. Sarpong, Nicholas D. Adams, Jeffrey Michael Axten, Amita M. Chaudhari, Dashyant Dhanak, Toshihiro Hamajima, Kenneth Allen Newlander, Cynthia A. Parrish, Jerry Leroy Adams, Domingos J. Silva, Jun Tang
  • Chemical compounds
    Patent number: 7482455
    Abstract: 3-carboxy quinoline derivatives, which are useful as YAK3 inhibitors are described herein. The described invention also includes methods of making such 3-carboxy quinoline derivatives as well as methods of using the same in the treatment of diseases mediated by inappropriate YAK3 activity.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: January 27, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Joelle L. Burgess, James F. Callahan, Toshihiro Hamajima, Satoru Ida, Ichiro Mori, Jun Tang
  • Pyrrolo [2,3,B] Pyridine Derivatives Useful As RAF Kinase Inhibitors
    Publication number: 20090018156
    Abstract: The present invention provides pyrrolo pyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.
    Type: Application
    Filed: January 31, 2007
    Publication date: January 15, 2009
    Inventors: Jun Tang, Masato Nakano, Toshihiro Hamajima
  • AZAINDOLE INHIBITORS OF AURORA KINASES
    Publication number: 20080081808
    Abstract: The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.
    Type: Application
    Filed: September 14, 2007
    Publication date: April 3, 2008
    Inventors: Martha Sarpong, Nicholas Adams, Jeffrey Axten, Amita Chaudhari, Dashyant Dhanak, Toshihiro Hamajima, Kenneth Newlander, Cynthia Parrish, Jerry Adams, Domingos Silva, Jun Tang
  • Chemical compounds
    Publication number: 20060106058
    Abstract: 3-carboxy quinoline derivatives, which are useful as YAK3 inhibitors are described herein. The described invention also includes methods of making such 3-carboxy quinoline derivatives as well as methods of using the same in the treatment of diseases mediated by inappropriate YAK3 activity.
    Type: Application
    Filed: October 15, 2003
    Publication date: May 18, 2006
    Inventors: Joelle Burgess, James Callahan, Toshihiro Hamajima, Satoru Ida, Ichiro Mori, Jun Tang