Patents by Inventor Toshihiro Kiho

Toshihiro Kiho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dihydroindolizinone derivative
    Patent number: 11530211
    Abstract: It is an object of the present invention to provide a new compound capable of efficiently inducing differentiation from pluripotent stem cells into insulin-producing cells. The object of the present invention is achieved by a compound represented by formula (I): wherein R1, R2, R3, n and A have the same meanings as defined in the description, respectively, or a salt thereof.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: December 20, 2022
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Toshihiro Kiho, Tatsuya Yano, Satoshi Komoriya, Taisaku Tanaka
  • METHOD FOR PRODUCING INSULIN-PRODUCING CELL USING DIHYDROINDOLIZINONE DERIVATIVES
    Publication number: 20220339260
    Abstract: As an approach of efficiently inducing differentiation from pluripotent stem cells into insulin-producing cells, provided is a method comprising the step of three-dimensionally culturing cells in a medium containing a dihydroindolizinone derivative.
    Type: Application
    Filed: July 7, 2020
    Publication date: October 27, 2022
    Applicants: TOKYO INSTITUTE OF TECHNOLOGY, DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Shoen Kume, Nobuaki Shiraki, Tatsuya Yano, Toshihiro Kiho
  • DIHYDROINDOLIZINONE DERIVATIVE
    Publication number: 20210053965
    Abstract: It is an object of the present invention to provide a new compound capable of efficiently inducing differentiation from pluripotent stem cells into insulin-producing cells. The object of the present invention is achieved by a compound represented by formula (I): wherein R1, R2, R3, n and A have the same meanings as defined in the description, respectively, or a salt thereof.
    Type: Application
    Filed: January 18, 2019
    Publication date: February 25, 2021
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Toshihiro Kiho, Tatsuya Yano, Satoshi Komoriya, Taisaku Tanaka
  • Chromone derivative having osteogenesis promoting effect
    Patent number: 9221811
    Abstract: Compounds or pharmacologically acceptable salts thereof for promoting osteogenesis, improving bone metabolism, preventing or treating bone fracture, preventing or treating a disease associated with bone metabolism, or in the field of orthopedics for the promotion of healing of bone fracture, a bone defect, and bone diseases such as osteoarthritis as well as in the field of dentistry for the treatment of periodontal disease and the stabilization of artificial tooth root.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: December 29, 2015
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Katsuhiro Kawakami, Toshihiro Kiho, Atsushi Tengeiji, Kentoku Gotanda, Kazumasa Aoki, Kazuki Yano
  • CHROMONE DERIVATIVE HAVING OSTEOGENESIS PROMOTING EFFECT
    Publication number: 20140349991
    Abstract: Compounds or pharmacologically acceptable salts thereof for promoting osteogenesis, improving bone metabolism, preventing or treating bone fracture, preventing or treating a disease associated with bone metabolism, or in the field of orthopedics for the promotion of healing of bone fracture, a bone defect, and bone diseases such as osteoarthritis as well as in the field of dentistry for the treatment of periodontal disease and the stabilization of artificial tooth root.
    Type: Application
    Filed: July 17, 2014
    Publication date: November 27, 2014
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Katsuhiro Kawakami, Toshihiro Kiho, Atsushi Tengeiji, Kentoku Gotanda, Kazumasa Aoki, Kazuki Yano