Patents by Inventor Toshihiro Kushibiki

Toshihiro Kushibiki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of differentiation induction to osteoblasts
    Patent number: 7829335
    Abstract: The invention offers a technique that selectively differentiation-induces mesenchymal stem cells, which can differentiate to cells that constitute various tissues and organs, to osteoblasts. In addition, the invention offers a technique that differentiation-induces mesenchymal stem cells to osteoblasts with a simple operation that needs only short time and that is noninvasive. The inventors have found that the switch for the differentiation induction to osteoblasts is turned on by translocating biological clock-relevant factors existing in mesenchymal stem cells from the cells' cytoplasm to the cells' nucleus. The inventors have also found that the switch can be turned on by irradiating the cells for a short time with a lightwave having a specific wavelength that is noninvasive.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: November 9, 2010
    Assignee: Sumitomo Electric Industries, Ltd.
    Inventors: Akira Inoue, Hitoshi Hatayama, Hiroshi Suganuma, Kunio Awazu, Toshihiro Kushibiki
  • Method of differentiation induction to osteoblasts
    Publication number: 20080057580
    Abstract: The invention offers a technique that selectively differentiation-induces mesenchymal stem cells, which can differentiate to cells that constitute various tissues and organs, to osteoblasts. In addition, the invention offers a technique that differentiation-induces mesenchymal stem cells to osteoblasts with a simple operation that needs only short time and that is noninvasive. The inventors have found that the switch for the differentiation induction to osteoblasts is turned on by translocating biological clock-relevant factors existing in mesenchymal stem cells from the cells' cytoplasm to the cells' nucleus. The inventors have also found that the switch can be turned on by irradiating the cells for a short time with a lightwave having a specific wavelength that is noninvasive.
    Type: Application
    Filed: August 20, 2007
    Publication date: March 6, 2008
    Applicant: Sumitomo Electric Industries, Ltd.
    Inventors: Akira Inoue, Hitoshi Hatayama, Hiroshi Suganuma, Kunio Awazu, Toshihiro Kushibiki