Patents by Inventor Toshiji Ichikawa
Toshiji Ichikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7147905Abstract: A laminate comprising at least a surface layer (I) and an adjacent layer (II) thereto, characterized in that the surface layer (I) comprises a cross-linked copolymer formed by cross-linking a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound, and the adjacent layer (II) comprises a hydrogenated copolymer formed by hydrogenating a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound; a multilayer tube comprising the laminate; and a medical device comprising the laminate, and/or the multilayer tube.Type: GrantFiled: October 16, 2002Date of Patent: December 12, 2006Assignees: Kuraray Co., Ltd., Kawasumi Laboratories, Inc.Inventors: Motohiro Fukuda, Naoto Fukuhara, Yukihiro Fujieda, Toshihide Nakashima, Koji Inai, Toshiji Ichikawa, Akira Ishida
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Patent number: 6977105Abstract: A multi-layered tube composed of at least two layers, each formed from a different resin, e.g. resin (I) or resin (II). Resin (I) contains 5 to 40 mass % of a polypropylene resin and 95 to 60 mass % of at least one hydrogenated copolymer. Resin (II) contains 45 to 100 mass % of a polypropylene resin and 55 to 0 mass % of a hydrogenated copolymer. The multi-layered tubes may be used in the field of medicine and provide tubing which is excellent in transparency, flexibility and anti-kinking properties, and which is durable during sterilization procedures with high-pressure steam. The multilayer tubing may also be safely disposed of as it generates no toxic gases, such as dioxin, when incinerated. The multilayered tubing has excellent connectability and may be bonded to other tubing using hot solvent bonding or solvent adhesion. The multilayered tubing which is free from generation of any toxic gas when incinerated, and which is excellent in hot solvent bonding or solvent adhesion to other tube.Type: GrantFiled: September 22, 2000Date of Patent: December 20, 2005Assignees: Kuraray Co., Ltd., Kawasumi Laboratories, Inc.Inventors: Yukihiro Fujieda, Masayasu Ogushi, Motohiro Fukuda, Toshiyuki Zento, Koichi Wada, Toshiji Ichikawa, Akira Ishida
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Publication number: 20040241478Abstract: A laminate comprising at least a surface layer (I) and an adjacent layer (II) thereto, characterized in that the surface layer (I) comprises a cross-linked copolymer formed by cross-linking a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound, and the adjacent layer (II) comprises a hydrogenated copolymer formed by hydrogenating a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound; a multilayer tube comprising the laminate; and a medical device comprising the laminate, and/or the multilayer tube.Type: ApplicationFiled: April 16, 2004Publication date: December 2, 2004Inventors: Motohiro Fukuda, Naoto Fukuhara, Yukihiro Fujieda, Toshihide Nakashima, Koji Inai, Toshiji Ichikawa, Akira Ishida
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Patent number: 4774963Abstract: A blood collector comprising a collection container in the form of a tube having a forward end adapted for drawing of blood into the container and an opened rear end, a closure unit adapted for closing the opened rear end of the collection container, and a mechanism including a valving element for allowing passage of air when blood is flowing into said container and preventing passage of air and blood when said container is filled with blood, said valving element of said mechanism including an air passage and a filter member communicating with the air passage, said filter member comprising water insoluble but water-swellable polymeric material and provided at least at the contact portion of the closure member with collected blood. Air contained in the blood collecting space of the collection container is expelled through the valving element by the collected blood which rises to a desired level for expelling air from said space practically completely.Type: GrantFiled: July 17, 1986Date of Patent: October 4, 1988Assignee: Terumo Kabushiki KaishaInventors: Toshiji Ichikawa, Atsushi Shimizu
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Patent number: 4770779Abstract: An apparatus for separating blood is provided with a closed end and a thixotropic gel-like sealant with a specific gravity intermediate between the gravities of serum and clot phases. A cavity is formed on the upper surface of said sealant. The sealant consists essentially of an .alpha.-olefin-dimaleate copolymer having a viscosity from 10,000 to 120,000 c.p. (25.degree. C.), to which a viscosity-specific gravity adjusting agent is added to adjust the specific gravity to 1.035-1.055. The cavity is formed in such a size that diameter of the upper surface is from 0.15 to 0.7 times the inner diameter of the apparatus and its depth is from 0.13 to 0.65 times the thickness of said sealant.Type: GrantFiled: July 1, 1987Date of Patent: September 13, 1988Assignee: Terumo CorporationInventors: Toshiji Ichikawa, Teruko Watanabe, Yoshimitsu Asada
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Patent number: 4735832Abstract: A container made of synthetic resin and provided at one portion thereof with at least one tightly closable opening, which container has on a surface thereof a continuous coating having a gas barrier characteristic comprising low permeability to oxygen and carbon dioxide by the plasma treatment reaction of a mixture of a silicon compound having the general formula I with a silicon compound having the general formula II: ##STR1## wherein m=1-5, n=1-5, R.sup.1 and R.sup.2 are C.sub.1 -C.sub.5 alkyl, C.sub.1 -C.sub.5 alkoxy or phenyl or OH.Type: GrantFiled: February 24, 1987Date of Patent: April 5, 1988Assignee: Terumo Kabushiki KaishaInventors: Toshiji Ichikawa, Yoshimitsu Asada, Ken Tatebe, Tooru Takahashi, Juuro Aoyagi, Takeshi Shimomura
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Patent number: 4708800Abstract: A porous hollow fiber membrane, comprising a polyolefin hollow fiber membrane of an annular cross section of substantial circle 150 to 300 .mu.m in inside diameter and 10 to 150 .mu.m in wall thickness, said hollow fiber membrane forming on the inner wall side thereof a tight layer of intimately bound fine polyolefin particles and on the outer wall side thereof a porous texture of fine polyolefin particles bound in chains and containing fine pores extended continuously form said inner wall side to said outer wall side.Type: GrantFiled: October 1, 1985Date of Patent: November 24, 1987Assignee: Terumo Kabushiki KaishaInventors: Toshiji Ichikawa, Kazuaki Takahara, Kazuhiro Shimoda, Yukio Seita, Makoto Emi
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Patent number: 4657541Abstract: A medical instrument formed of a wall of flexible vinyl chloride resin and enabled to be flattened is disclosed. In this instrument, the inner wall whose opposed surfaces come into mutual contact when the instrument is flattened is made of a flexible vinyl chloride resin composition containing cross-linked vinyl chloride resin particles and, therefore, enabled to form minute protuberances and depressions in the inner wall surfaces. This instrument is useful as bags for holding medical fluids and blood.Type: GrantFiled: June 4, 1985Date of Patent: April 14, 1987Assignee: Terumo Kabushiki KaishaInventors: Toshiji Ichikawa, Yoshinori Ohachi
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Patent number: 4617941Abstract: A blood collector comprising a collection container in the form of a tube having a forward end adapted for drawing of blood into the container and an opened rear end, a closure unit adapted for closing the opened rear end of the collection container, and a mechanism including a valving element for allowing passage of air when blood is flowing into said container and preventing passage of air and blood when said container is filled with blood, said valving element of said mechanism including an air passage and a filter member communicating with the air passage, said filter member comprising water insoluble but water-swellable polymeric material and provided at least at the contact portion of the closure member with collected blood. Air contained in the blood collecting space of the collection container is expelled through the valving element by the collected blood which rises to a desired level for expelling air from said space practically completely.Type: GrantFiled: August 6, 1984Date of Patent: October 21, 1986Assignee: TerumoInventors: Toshiji Ichikawa, Atsushi Shimizu
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Patent number: 4595021Abstract: A blood collector includes a cylindrical body having a closed end and an open end, and a hollow body is arranged coaxially at the closed end of the cylindrical body and has a hole communicating with the interior of the cylindrical body. A columnar body is arranged within the cylindrical body to be in tight contact with an inner wall thereof, with a distal end defining a blood collection space with the closed end of the cylindrical body. Further, the columnar body has a hole which allows the blood collection space to communicate with the outside. A freeze-dried blood anticoagulant mass is placed inside the blood collection space to cover an inner surface of the closed end of the cylindrical body and to block the hole of the hollow body. A filter is arranged across the hole of the columnar body. The filter is permeable to gases and impermeable to blood at least before being brought into contact with blood in the collection space.Type: GrantFiled: June 4, 1985Date of Patent: June 17, 1986Assignee: Terumo CorporationInventors: Atsushi Shimizu, Toshiji Ichikawa
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Patent number: 4560720Abstract: Medical articles made of a resin composition comprising a polyvinyl chloride and a tetracarboxylic tetraester are provided. As examples of the tetracarboxylic tetraester are mentioned tetra(2-ethylhexyl) 3,3',4,4'-biphenylethertetracarboxylate, tetra(2-ethylhexyl) 3,3',4,4'-biphenylmethanetetracarboxylate, tetra(n-dodecyl) 2,3,3',4'-biphenyl-1,1-ethanetetracarboxylate, tetra(2-ethylhexyl) 3,3',4,4'-biphenyl-2,2-propanetetracarboxylate and the like. The tetracarboxylic tetraester is incorporated in an amount from 20 to 120, preferably from 30 to 100 parts by weight per 100 parts by weight of the polyvinyl chloride. As dissolution and migration to the surface of the article of the plasticizer tetracarboxylic tetraester are low in the medical articles, said medical articles produce no adverse effects upon body fluids such as blood when contacted. Examples of preferred medical articles are blood preservation vessels, catheters and blood transfusion sets.Type: GrantFiled: October 17, 1983Date of Patent: December 24, 1985Assignee: Terumo Kabushiki KaishaInventors: Juuro Aoyagi, Toshiji Ichikawa, Mikio Koide, Takeshi Shimomura
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Patent number: 4547191Abstract: A medical solution transfusion circuit has a transparent cylindrical pumping body, a hard cap mounted on at least one end of said transparent cylindrical pumping body, and a flexible tube for communicating with said transparent cylindrical pumping body to transport a medical solution. The transparent cylindrical pumping body comprises a propylene/.alpha.-olefin copolymer.Type: GrantFiled: August 13, 1984Date of Patent: October 15, 1985Assignee: Terumo Kabushiki KaishaInventors: Toshiji Ichikawa, Yoshinori Ohhachi, Zensho Kanda
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Patent number: 4507415Abstract: Irradiation-sterilizable medical articles molded from a propylene polymer composition in which stabilizers are incorporated. Said composition comprises from 0.01 to 0.4 part by weight of each of a specific hindered amine and a specific phenol or its phosphite ester compound incorporated per 100 parts by weight of a propylene polymer with a weight-average molecular-weight to number-average molecular-weight ratio of 5 or below. The above-mentioned composition may additionally contain a sorbitol derivative as the nucleating agent. Medical articles produced from said composition by molding, for example, syringes are suitable for irradiation sterilization. Said medical articles when irradiated undergo little reduction in quality of the material and are accompanied by little bleeding or degradation of the incorporated stabilizers and nucleating agent.Type: GrantFiled: March 23, 1983Date of Patent: March 26, 1985Assignee: Terumo Kabushiki KaishaInventors: Masaaki Kasai, Toshiji Ichikawa, Kimiho Kosegaki
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Patent number: 4444330Abstract: A stopper for hermetically sealing the opening of a medical container is made of an injection-moldable polymeric material containing a blend of 30 to 90% by weight of a butyl-based rubber and 70 to 10% by weight of a thermoplastic elastomer.Type: GrantFiled: July 27, 1982Date of Patent: April 24, 1984Assignee: Terumo Kabushiki KaishaInventors: Masaaki Kasai, Toshiji Ichikawa
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Patent number: 4426290Abstract: An apparatus for separating blood is provided with a closed end and a thixotropic gel-like sealant with a specific gravity intermediate between the gravities of serum and clot phases. A cavity is formed on the upper surface of said sealant. The sealant consists essentially of an .alpha.-olefin-dimaleate copolymer having a viscosity from 10,000 to 120,000 c.p. (25.degree. C.), to which a viscosity-specific gravity adjusting agent is added to adjust the specific gravity to 1.035-1.055. The cavity is formed in such a size that diameter of the upper surface is from 0.15 to 0.7 times the inner diameter of the apparatus and its depth is from 0.13 to 0.65 times the thickness of said sealant.Type: GrantFiled: March 11, 1983Date of Patent: January 17, 1984Assignee: Terumo CorporationInventors: Toshiji Ichikawa, Teruko Watanabe, Yoshimitsu Asada
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Patent number: 4303070Abstract: A syringe includes an outer cylinder, a gasket having at least one part which slidably contacts the inner wall of the cylinder and being made of an elastomer material including a block copolymer having styrene units at both terminal ends, and means for sliding the gasket inside the cylinder. The slidably contacting part is compressed inside the cylinder at a compressiblity C (%) of a predetermined range selected according to a particular inner diameter of the cylinder. The product of the total contact area S (mm.sup.2) at the compressibility C (%) of the contacting part with the inner wall of the cylinder with the compressibility C (%) is about 350 to about 900.Type: GrantFiled: September 22, 1980Date of Patent: December 1, 1981Assignee: Terumo CorporationInventors: Toshiji Ichikawa, Teruko Watanabe
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Patent number: 4177182Abstract: Polyvinyl chloride series resin compositions comprising 100 parts by weight of polyvinyl chloride series resin, 20 to 80 parts by weight of a plasticizer and 0.2 to 7 parts by weight of silicone oil, which minimize the elution of the plasticizer, and a method of manufacturing polyvinyl chloride series resin compositions which is characterized by emulsifying said silicone oil in advance with part of said plasticizer and adding an emulsion thus formed to said resin compositions.Type: GrantFiled: September 23, 1975Date of Patent: December 4, 1979Assignee: Terumo Corp.Inventors: Toshiji Ichikawa, Osamu Minoo