Abstract: An antibody-drug conjugate represented by formula (I): (where Ab is an antibody, X is a group represented by formula (X-1), formula (X-2) or formula (X-3): (where at the left represents the binding site with NH and at the right represents the binding side with D), D is a group represented by formula (D-1) or formula (D-2): (where represents the binding site with X), and n is in the range of about 1 to about 8).

Abstract: A refrigerant flow path switch arranged between an outdoor device and each of multiple indoor devices controls a refrigerant flow and is provided with a housing; a refrigerant flow path switching circuit having multiple refrigerant flow path switching circuits, wherein each refrigerant flow path switching circuit includes a high/low pressure gas pipe, a low pressure gas pipe, a high/low pressure electric valve provided at the high/low pressure gas pipe, and a low pressure electric valve provided at the low pressure gas pipe. A liquid pipe assembly is arranged in the housing and has multiple liquid pipes connected to the multiple indoor devices. A first divider plate is provided between adjacent ones of the refrigerant flow path switching circuits and divides an internal space of the housing such that a space divided by the first divider plate is in a substantially cubic shape, which is filled with a foaming agent.

Abstract: An indoor unit of an air conditioner includes multiple blow ports and multiple louvers each provided at the blow ports and configured to adjust a blowing direction. Each louver is, upon stop of the indoor unit, rotated in the direction of closing the blow port, the angle of the louver upon stop of the indoor unit being a fully-closed angle. When the minimum angle among louver angles settable by the remote controller is taken as a first angle and the maximum angle is taken as a second angle, the louver angles of a part of the multiple blow ports are, under a preset predetermined operation condition, set to a third angle greater than the fully-closed angle as the louver angle upon stop of the indoor unit and smaller than the first angle, and the louvers of the other blow ports perform louver operation settable from a remote controller.

Abstract: A refrigerant flow path switch arranged between an outdoor device and each of multiple indoor devices controls a refrigerant flow and is provided with a housing; a refrigerant flow path switching circuit having multiple refrigerant flow path switching circuits, wherein each refrigerant flow path switching circuit includes a high/low pressure gas pipe, a low pressure gas pipe, a high/low pressure electric valve provided at the high/low pressure gas pipe, and a low pressure electric valve provided at the low pressure gas pipe. A liquid pipe assembly is arranged in the housing and has multiple liquid pipes connected to the multiple indoor devices. A first divider plate is provided between adjacent ones of the refrigerant flow path switching circuits and divides an internal space of the housing such that a space divided by the first divider plate is in a substantially cubic shape, which is filled with a foaming agent.

Abstract: An electric vehicle includes front and rear wheels, a battery, an electric motor that drives at least one of the front and rear wheels, an accelerator, and a mode shift operator that is operated by a user in order to switch drive modes. The electric vehicle includes a driving force characteristics setter that sets, for each of the plurality of drive modes, driving force characteristics which are characteristics of an accelerator opening degree and a target motor driving force for the rotational speed of the electric motor. The electric vehicle further includes a controller which shifts up, according to an operation of the mode shift operator, the drive mode from a first drive mode to a second drive mode and which controls the target motor driving force according to the driving force characteristics. When a shift-down prohibition condition is met, the controller prohibits a shift down from the second drive mode to the first drive mode.

Abstract: A battery with increased capacity is provided in a straddled electric vehicle including a drive unit provided on a rear arm for supporting a rear wheel such that the rear wheel is rotatable. A power supply unit is located in a vehicle body frame to supply electric power to the drive unit. The drive unit includes a motor that overlaps the rear wheel in a side view of the vehicle. The power supply unit includes a battery and a controller. The controller supplies electric power stored in the battery to the drive unit. The vehicle body frame includes a head pipe and a pivot shaft. The pivot shaft supports the rear arm such that it is swingable. The power supply unit is located between the head pipe and pivot shaft in a side view of the vehicle.

Abstract: An electric vehicle includes front and rear wheels, a battery, an electric motor that drives at least one of the front and rear wheels, an accelerator, and a mode shift operator that is operated by a user in order to switch drive modes. The electric vehicle includes a driving force characteristics setter that sets, for each of the plurality of drive modes, driving force characteristics which are characteristics of an accelerator opening degree and a target motor driving force for the rotational speed of the electric motor. The electric vehicle further includes a controller which shifts up, according to an operation of the mode shift operator, the drive mode from a first drive mode to a second drive mode and which controls the target motor driving force according to the driving force characteristics. When a shift-down prohibition condition is met, the controller prohibits a shift down from the second drive mode to the first drive mode.

Abstract: A battery with increased capacity is provided in a straddled electric vehicle including a drive unit provided on a rear arm for supporting a rear wheel such that the rear wheel is rotatable. A power supply unit is located in a vehicle body frame to supply electric power to the drive unit. The drive unit includes a motor that overlaps the rear wheel in a side view of the vehicle. The power supply unit includes a battery and a controller. The controller supplies electric power stored in the battery to the drive unit. The vehicle body frame includes a head pipe and a pivot shaft. The pivot shaft supports the rear arm such that it is swingable. The power supply unit is located between the head pipe and pivot shaft in a side view of the vehicle.