Patents by Inventor Toshimitsu Konno

Toshimitsu Konno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lyophilized pharmaceutical composition of neocarzinostatin derivative
    Patent number: 5026772
    Abstract: A lyophilized pharmaceutical composition comprised of a neocarzinostatin derivative having the formula (SMA)-(NCS)-(SMA), is made by a method including dissolving the neocarzinostatin derivative and stabilizing agent comprising at least one saccharide selected from the group consisting of monosaccharides, disaccharides and dextran in an aqueous buffer solution having a pH ranging from about 7.5 to about 9.5, the stabilizing agent being present in an amount by weight (titer) which is at least equal to that of the neocarzinostatin derivative, to provide a solution; adjusting the pH of the solution to provide a pH-adjusted solution having a pH of about 8.0.+-.0.5; sterilizing the pH-adjusted solution by filtration to provide a sterilized solution; and lyophilizing the sterilized solution.
    Type: Grant
    Filed: August 29, 1988
    Date of Patent: June 25, 1991
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Mitsugu Kobayashi, Go Ohtani, Jun Sekino, Toshimitsu Konno, Hiroshi Maeda
  • Oily composition of aclarubicin or hydrochloride thereof
    Patent number: 4772590
    Abstract: An oily composition of aclarubicin or aclarubicin hydrochloride comprising aclarubicin or aclarubicin hydrochloride; at least one fatty acid selected from saturated medium chain fatty acids, unsaturated medium chain fatty acids and unsaturated long chain fatty acids; and at least one fats and oils selected from iodized oils and vegetable oils.
    Type: Grant
    Filed: June 27, 1986
    Date of Patent: September 20, 1988
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Hiroitsu Kawata, Shunji Hasumi, Akira Okada, Masayoshi Aruga, Toshimitsu Konno, Ken Iwai, Hiroshi Maeda
  • Oily compositions of antitumor drugs
    Patent number: 4578391
    Abstract: An oily composition of an antitumor drug comprising at least one sparingly oil soluble or water-soluble antitumor drug, at least one fat or oil, and at least one solubilizing adjuvant in an oily vehicle selected from the group consisting of crown ether, lecithin, polyethylene glycol, propylene glycol, vitamin E, polyoxyethylene alkylether, and sucrose esters of fatty acids.
    Type: Grant
    Filed: January 13, 1983
    Date of Patent: March 25, 1986
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Hiroitsu Kawata, Tadayoshi Ohmura, Shunji Hasumi, Yutaka Konno, Masayoshi Aruga, Seiki Tashiro, Toshimitsu Konno, Ken Iwai