Abstract: An information processing apparatus is configured to acquire a rental request for a company vehicle used for a business operation of a company, select the company vehicle, in response to the rental request, from among private vehicles that are used by employees of the company when they go to work and are available as the company vehicle, and provide, in a case where a private vehicle is selected in selecting the company vehicle in response to the rental request and rented out as the company vehicle, to a requestor who has sent the rental request availability information that enables the requestor to use the selected private vehicle.

Abstract: The present disclosure provides a technique to encourage a user who is lent a vehicle to obey manners at time of using the vehicle. In the present disclosure, a controller executes: informing a user who is lent a vehicle of information indicating a plurality of manners provisions about use of the vehicle; acquiring a picked-up image of the vehicle about the plurality of manners provisions at time of returning the vehicle; and calculating an evaluation value for obedience of the plurality of manners provisions, based on the picked-up image.

Abstract: In a system for renting vehicles to users, the operation rate of the vehicles is improved. An information processing apparatus for managing the rental of vehicles to users is configured to perform: generating a rental schedule of a vehicle for a first user; obtaining demand data related to a demand for the vehicle; and changing, based on the demand data, a vehicle return point included in the rental schedule, the vehicle return point being a point at which the first user returns the vehicle.

Abstract: An affinity support having improved binding capacity for target proteins. An immunoglobulin-binding protein including a mutant immunoglobulin-binding domain, an affinity support including a solid-phase support and the immunoglobulin-binding protein immobilized thereto. The mutant immunoglobulin-binding domain consists of an amino acid sequence having at least 85% identity with an amino acid sequence of any of SEQ ID NOs: 1 to 12.

Abstract: An information processing apparatus includes a controller configured to acquire, in relation to a first vehicle associated with a predetermined organization, information about a schedule including a purpose of use, output, in a case where the purpose of use of the first vehicle is business activity, first use-settings information indicating settings regarding use of one or more options mounted in the first vehicle, and output, in a case where the purpose of use of the first vehicle is personal use, second use-settings information indicating settings regarding use of the one or more options mounted in the first vehicle.

Abstract: In a system for renting vehicles to users, the operation rate of the vehicles is improved. An information processing apparatus for managing the rental of vehicles to users is configured to perform: generating a rental schedule of a vehicle for a first user; obtaining demand data related to a demand for the vehicle; and changing, based on the demand data, a vehicle return point included in the rental schedule, the vehicle return point being a point at which the first user returns the vehicle.

Abstract: An information processing apparatus includes a controller that receives, from a terminal of a first user among a plurality of users including a user not belonging to a predetermined organization, a request for use of to a first vehicle associated with the predetermined organization for other than a business activity in the predetermined organization, and registers, in response to the request, a schedule for use of the first vehicle for other than the business activity. Moreover, a user terminal transmits, to a predetermined apparatus, the request for use of first vehicle associated with the predetermined organization for other than the business activity in the predetermined organization from the first user among a plurality of users including a user not belonging to the predetermined organization, and receives, from the predetermined apparatus, in response to the request, a schedule for use of the first vehicle for other than the business activity.

Abstract: The present disclosure enables equipment not provided in a company vehicle to be rented out to a user together with the company vehicle. An information processing apparatus of the present disclosure includes a controller that is configured to acquire a use application to privately use a company vehicle that is used by the company for business activity, from a user who is an employee of a company, specify equipment that is able to be rented out together with the company vehicle to be rented out to the user and that is not provided in the company vehicle, as recommended equipment, based on the use application, and supply guide information suggesting rental of the recommended equipment to a user terminal.

Abstract: The present disclosure provides a technique to encourage a user who is lent a vehicle to obey manners at time of using the vehicle. In the present disclosure, a controller executes: informing a user who is lent a vehicle of information indicating a plurality of manners provisions about use of the vehicle; acquiring a picked-up image of the vehicle about the plurality of manners provisions at time of returning the vehicle; and calculating an evaluation value for obedience of the plurality of manners provisions, based on the picked-up image.

Abstract: An information processing apparatus is configured to acquire a rental request for a company vehicle used for a business operation of a company, select the company vehicle, in response to the rental request, from among private vehicles that are used by employees of the company when they go to work and are available as the company vehicle, and provide, in a case where a private vehicle is selected in selecting the company vehicle in response to the rental request and rented out as the company vehicle, to a requestor who has sent the rental request availability information that enables the requestor to use the selected private vehicle.

Abstract: An affinity carrier may have improved alkali resistance. An immunoglobulin-binding protein containing a mutant polypeptide chain, as well as an affinity carrier containing a solid-phase carrier to which the immunoglobulin-binding protein is bound, may be a mutant polypeptide chain having an amino acid sequence having at least 85% identity to an amino acid sequence indicated by any of SEQ ID NO: 1-6 and 57-62, having a predetermined mutation, and having immunoglobulin-binding activity.

Abstract: Provided are a production method of a pregabalin-containing composition, which suppresses crystallization of pregabalin, and a pregabalin-containing composition that shows suppressed crystallization of Pregabalin. The production method of the pregabalin-containing composition of the present invention contains steps of: (1) dissolving pregabalin in an aqueous solution of an acid to prepare an aqueous solution of a salt of pregabalin; (2) mixing the aqueous solution of pregabalin salt and a hydrophilic resin to prepare a mixture thereof; and (3) concentrating the mixture; wherein the acid has an acid dissociation constant lower than that of pregabalin.

Abstract: Provided are a production method of a pregabalin-containing composition, which suppresses crystallization of pregabalin, and a pregabalin-containing composition that shows suppressed crystallization of Pregabalin. The production method of the pregabalin-containing composition of the present invention contains steps of: (1) dissolving pregabalin in an aqueous solution of an acid to prepare an aqueous solution of a salt of pregabalin; (2) mixing the aqueous solution of pregabalin salt and a hydrophilic resin to prepare a mixture thereof; and (3) concentrating the mixture; wherein the acid has an acid dissociation constant lower than that of pregabalin.