Patents by Inventor Toshinori Agatsuma

Toshinori Agatsuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody against tumor specific antigen as target
    Patent number: 7855056
    Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: December 21, 2010
    Assignee: Sankyo Co., Ltd.
    Inventors: Kimihisa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
  • ANTI-EPHA2 ANTIBODY
    Publication number: 20100183618
    Abstract: Problem to Be Solved It is intended to provide an antibody having an inhibitory activity against cell malignant transformation and/or tumor cell growth, etc. Solution The present invention provides an antibody which recognizes an epitope recognized by an antibody produced by a hybridoma SH348-1 (FERM BP-10836) or a hybridoma SH357-1 (FERM BP-10837), an antibody produced by the hybridoma SH348-1 or the hybridoma SH357-1, an antibody obtained by humanizing the antibody produced by the hybridoma SH348-1 or the hybridoma SH357-1, a pharmaceutical agent comprising the antibody as an active ingredient, etc.
    Type: Application
    Filed: February 25, 2010
    Publication date: July 22, 2010
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Jun Hasegawa, Toshiaki Ohtsuka, Atsushi Urano, Junko Yamaguchi, Toshinori Agatsuma, Kaori Nakahara, Takeshi Takizawa
  • Antibody against tumor specific antigen as target
    Patent number: 7741447
    Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.
    Type: Grant
    Filed: October 15, 2007
    Date of Patent: June 22, 2010
    Assignee: Sankyo Co., Ltd.
    Inventors: Kimihasa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
  • ANTIBODY AGAINST TUMOR SPECIFIC ANTIGEN AS TARGET
    Publication number: 20080146785
    Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.
    Type: Application
    Filed: October 15, 2007
    Publication date: June 19, 2008
    Inventors: Kimihasa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
  • Antibody against tumor specific antigen as target
    Patent number: 7361340
    Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.
    Type: Grant
    Filed: September 9, 2005
    Date of Patent: April 22, 2008
    Assignee: Sankyo Co., Ltd.
    Inventors: Kimihasa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
  • Antibody against tumor specific antigen as target
    Publication number: 20070166312
    Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.
    Type: Application
    Filed: March 9, 2004
    Publication date: July 19, 2007
    Applicant: Sankyo Company , Limited
    Inventors: Kimihisa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
  • Oculospanin as a tumor specific antigen and methods and compositions utilizing same
    Publication number: 20070025996
    Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer.
    Type: Application
    Filed: January 31, 2006
    Publication date: February 1, 2007
    Inventors: Kimihisa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
  • Oncogene HOXB13 and its siRNAs
    Publication number: 20060265765
    Abstract: A method of producing cancer cells using an oncogene, a method of detecting cancer using the cancer cell, a method of screening compounds having cancer therapeutic and/or preventive effects and a cancer therapeutic and/or preventive pharmaceutical composition. There could be provided a method of detecting cancer using the expression of HOXB13 as an indicator wherein HOXB13 gene is excessively expressed in a cell, and a cell line in which cell growth ability is changed is selected; a method of screening compounds having novel cancer therapeutic and/or preventive effects by using OXB13; a pharmaceutical composition; and a method of treating cancer using said pharmaceutical composition.
    Type: Application
    Filed: May 19, 2005
    Publication date: November 23, 2006
    Applicant: SANKYO COMPANY, LIMITED
    Inventors: Toshinori Agatsuma, Keisuke Fukuchi, Satoko Nishimura
  • Antibody against tumor specific antigen as target
    Publication number: 20060127405
    Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.
    Type: Application
    Filed: September 9, 2005
    Publication date: June 15, 2006
    Applicant: Sankyo Company, Limited
    Inventors: Kimihasa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai