Patents by Inventor Toshio Inui

Toshio Inui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240009268
    Abstract: A macrophage activator containing a Gc protein is provided by a simple process. The macrophage activator contains a Gc protein with no N-acetylgalactosamine attached thereto.
    Type: Application
    Filed: December 8, 2021
    Publication date: January 11, 2024
    Applicant: SAISEI PHARMA CO., LTD.
    Inventor: Toshio Inui
  • Patent number: 11464835
    Abstract: An object of the present invention is to provide an enzyme-treated milk product, a method for preparing the same, a composition thereof comprising a pharmaceutical composition, and a product thereof comprising a pharmaceuticals. The enzyme-treated milk product can be obtained by a method for producing an enzyme-treated milk product including a step for bringing milk into contact with ?-galactosidase.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: October 11, 2022
    Assignee: SAISEI PHARMA CO., LTD.
    Inventor: Toshio Inui
  • Publication number: 20210330710
    Abstract: Provided are inflammatory cytokine production inhibitors which inhibit the production of the inflammatory cytokines TNF-? and IL-1? and can be applied to drugs effective against inflammatory diseases caused by overproduction of these inflammatory cytokines, such as chronic inflammation (e.g., rheumatoid arthritis, ulcerative colitis) and Crohn's disease, as well as type 2 diabetes, depression, obesity, sepsis, atherosclerosis, dermatitis, dementia, schizophrenia, and Parkinson's disease, and also to foods and drinks such as health foods. The inflammatory cytokine production inhibitors contain as an active ingredient an enzyme-treated whey obtained by contacting whey with ?-galactosidase. The enzyme-treated whey is obtained by further contacting with sialidase.
    Type: Application
    Filed: September 4, 2019
    Publication date: October 28, 2021
    Applicant: SAISEI PHARMA CO., LTD.
    Inventor: Toshio Inui
  • Publication number: 20210196780
    Abstract: Inflammatory cytokine production inhibitors containing a tomato extract as an active ingredient, which inhibit the production of the inflammatory cytokines TNF-? and IL-6 and can be applied to drugs effective against inflammatory diseases caused by overproduction of these inflammatory cytokines, such as rheumatoid arthritis, ulcerative colitis, Crohn's disease, and type 2 diabetes, as well as to foods and drinks such as health foods, wherein the tomato extract is a raw tomato extract that is a high-molecular-weight fraction having a molecular weight of 10,000 or higher obtained by molecular weight fractionation.
    Type: Application
    Filed: July 16, 2019
    Publication date: July 1, 2021
    Applicant: SAISEI PHARMA CO., LTD.
    Inventor: Toshio Inui
  • Patent number: 10322147
    Abstract: An object of the present invention is to provide a method of preparing an enzyme-treated bovine colostrum, comprising a step of bringing a bovine colostrum into contact with ?-galactosidase, and a pharmaceutical composition comprising the enzyme-treated bovine colostrum. The enzyme-treated bovine colostrum is useful for treatment, prevention, amelioration and maintenance of remission of diseases such as a cancer and an infectious disease.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: June 18, 2019
    Assignee: SAISEI PHARMA CO., LTD.
    Inventors: Yoshihiro Uto, Hitoshi Hori, Toshio Inui, Kentaro Kubo
  • Publication number: 20180133292
    Abstract: An object of the present invention is to provide an enzyme-treated milk product, a method for preparing the same, a composition thereof comprising a pharmaceutical composition, and a product thereof comprising a pharmaceuticals. The enzyme-treated milk product can be obtained by a method for producing an enzyme-treated milk product including a step for bringing milk into contact with ?-galactosidase.
    Type: Application
    Filed: May 31, 2016
    Publication date: May 17, 2018
    Applicant: SAISEI PHARMA CO., LTD.
    Inventor: Toshio INUI
  • Patent number: 9670268
    Abstract: An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with ?-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: June 6, 2017
    Assignee: SAISEI MIRAI CLINIC
    Inventors: Yoshihiro Uto, Hitoshi Hori, Toshio Inui, Kentaro Kubo
  • Publication number: 20160296566
    Abstract: An object of the present invention is to provide a method of preparing an enzyme-treated bovine colostrum, comprising a step of bringing a bovine colostrum into contact with ?-galactosidase, and a pharmaceutical composition comprising the enzyme-treated bovine colostrum. The enzyme-treated bovine colostrum is useful for treatment, prevention, amelioration and maintenance of remission of diseases such as a cancer and an infectious disease.
    Type: Application
    Filed: December 11, 2014
    Publication date: October 13, 2016
    Applicant: SAISEI PHARMA CO., LTD.
    Inventors: Yoshihiro UTO, Hitoshi HORI, Toshio INUI, Kentaro KUBO
  • Patent number: 9409972
    Abstract: An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with ?-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: August 9, 2016
    Assignees: TOKUSHIMA UNIVERSITY, SAISEI MIRAI CLINIC
    Inventors: Yoshihiro Uto, Hitoshi Hori, Toshio Inui, Kentaro Kubo
  • Publication number: 20150152163
    Abstract: An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with ?-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method.
    Type: Application
    Filed: January 21, 2015
    Publication date: June 4, 2015
    Applicants: THE UNIVERSITY OF TOKUSHIMA, SAISEI MIRAI CLINIC
    Inventors: Yoshihiro UTO, Hitoshi HORI, Toshio INUI, Kentaro KUBO
  • Publication number: 20140213522
    Abstract: An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with ?-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method.
    Type: Application
    Filed: February 28, 2014
    Publication date: July 31, 2014
    Applicants: THE UNIVERSITY OF TOKUSHIMA, SAISEI MIRAI CLINIC
    Inventors: Yoshihiro UTO, Hitoshi HORI, Toshio INUI, Kentaro KUBO
  • Patent number: 8747919
    Abstract: An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with ?-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: June 10, 2014
    Assignees: Saisei Mirai Clinic, The University of Tokushima
    Inventors: Yoshihiro Uto, Hitoshi Hori, Toshio Inui, Kentaro Kubo
  • Publication number: 20130243880
    Abstract: An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and prevention of diseases such as a cancer and an infectious disease, and a method of preparing the same. The present invention relates to a method of preparing a pharmaceutical composition comprising an enzyme-treated human serum, comprising a step of bringing the human serum into contact with ?-galactosidase and, to a pharmaceutical composition comprising an enzyme-treated human serum obtained by the preparation method.
    Type: Application
    Filed: September 7, 2012
    Publication date: September 19, 2013
    Applicants: THE UNIVERSITY OF TOKUSHIMA, SAISEI MIRAI CLINIC
    Inventors: Yoshihiro Uto, Hitoshi Hori, Toshio Inui, Kentaro Kubo
  • Patent number: 7451597
    Abstract: An engine includes an electric supercharger as a first supercharger, a turbocharger as a second supercharger, a secondary air supply passage, a secondary air valve and a catalyst. The electric supercharger is provided in an intake passage which is in communication with a combustion chamber, and supercharges intake air into the combustion chamber. The turbocharger is provided in the intake passage in series with respect to the electric supercharger, and supercharges intake air to the combustion chamber. The secondary air supply passage and the secondary air valve supply air compressed by the electric supercharger to a discharge passage which is in communication with the combustion chamber. The catalyst is provided in the discharge passage to purify exhaust gas.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: November 18, 2008
    Assignee: Mitsubishi Jidosha Kogyo Kabushiki Kaisha
    Inventors: Ichiyo Kojima, Toshio Inui, Hideo Nakai, Tetsuo Kataoka
  • Patent number: 7215951
    Abstract: A test procedure control unit outputs control information including time setting information along a procedure for carrying out a transition test of a connection state of a mobile communication terminal (UE) of a cellular system. A transmitting/receiving unit transmits test signals corresponding to cells toward the UE in accordance with the control information, and receives a response signal from the UE. A reception measurement unit measures a transition time of the connection state among the cells of the UE, in accordance with the response signal. A deciding unit receives a measured result of the transition time, and decides whether or not the connection state of the UE is transiting in accordance with the scheduled time-passage. The indicating unit causes the display unit to indicate, the decided result transition among the cells in accordance with the time-passage, so as to be visually recognizable on a single coordinate.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: May 8, 2007
    Assignee: Amritsu Corporation
    Inventors: Hideki Tanaka, Ryu Morita, Toshio Inui
  • Publication number: 20060064981
    Abstract: An engine includes an electric supercharger as a first supercharger, a turbocharger as a second supercharger, a secondary air supply passage, a secondary air valve and a catalyst. The electric supercharger is provided in an intake passage which is in communication with a combustion chamber, and supercharges intake air into the combustion chamber. The turbocharger is provided in the intake passage in series with respect to the electric supercharger, and supercharges intake air to the combustion chamber. The secondary air supply passage and the secondary air valve supply air compressed by the electric supercharger to a discharge passage which is in communication with the combustion chamber. The catalyst is provided in the discharge passage to purify exhaust gas.
    Type: Application
    Filed: September 28, 2005
    Publication date: March 30, 2006
    Inventors: Ichiyo Kojima, Toshio Inui, Hideo Nakai, Tetsuo Kataoka
  • Publication number: 20040192214
    Abstract: A test procedure control unit outputs control information including time setting information along a procedure for carrying out a transition test of a connection state of a mobile communication terminal (UE) of a cellular system. A transmitting/receiving unit transmits test signals corresponding to cells toward the UE in accordance with the control information, and receives a response signal from the UE. A reception measurement unit measures a transition time of the connection state among the cells of the UE, in accordance with the response signal. A deciding unit receives a measured result of the transition time, and decides whether or not the connection state of the UE is transiting in accordance with the scheduled time-passage. The indicating unit causes the display unit to indicate, the decided result transition among the cells in accordance with the time-passage, so as to be visually recognizable on a single coordinate.
    Type: Application
    Filed: March 16, 2004
    Publication date: September 30, 2004
    Applicant: ANRITSU CORPORATION
    Inventors: Hideki Tanaka, Ryu Morita, Toshio Inui
  • Patent number: 6257207
    Abstract: A startup control apparatus of an internal combustion engine is provided wherein when an engine starting capability determining device determines that the engine can be successfully started even if driving of part of the fuel injector valves is stopped during engine startup, the fuel injection is stopped with respect to the part of the fuel injector valves. With this arrangement, overshoot of the engine speed that would otherwise occur upon the start of the engine can be suppressed, and unburned fuel components can be prevented from being discharged, thus assuring improved exhaust gas characteristics and improved fuel efficiency.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: July 10, 2001
    Assignee: Mitsubishi Jidosha Kogyo Kabushiki Kaisha
    Inventors: Toshio Inui, Katsuhiko Miyamoto, Yoshiyuki Hoshiba