Patents by Inventor Toshio Kakimoto

Toshio Kakimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for purification of crude urokinase
    Patent number: 4160697
    Abstract: An aqueous solution of crude urokinase is contacted with a cross-linked diethylaminoethyl-agarose to have pyrogens adsorbed thereon. The effluent is then contacted with a water-insoluble, hydrophilic polysaccharide having a group of the formula:--CH.sub.2 CH(OH)CH.sub.2 Rwherein R is sulfothio, sulfo or p-sulfophenylamino, and the urokinase adsorbed is eluted from said polysaccharide. Pyrogen-free urokinase is thereby obtained in a high purity as the eluate.
    Type: Grant
    Filed: March 23, 1978
    Date of Patent: July 10, 1979
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Ichiro Chibata, Toshio Kakimoto, Yoshiaki Kakie, Takeji Shibatani, Noriyuki Nishimura