Patents by Inventor Toshio Kaneko
Toshio Kaneko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10138240Abstract: A crystal of a compound represented by the general formula (I) or a pharmacologically acceptable salt thereof has an excellent LCAT-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, or renal disease, particularly, an anti-arteriosclerotic agent, wherein R1 is a hydrogen atom or a hydroxy group, and R is a 2-(trifluoromethyl)pyrimidin-5-yl group or a 5-(trifluoromethyl)pyrazin-2-yl group.Type: GrantFiled: June 10, 2016Date of Patent: November 27, 2018Assignee: Daiichi Sankyo Company, LimitedInventors: Katsuhiro Kobayashi, Toshio Kaneko
-
Publication number: 20180170926Abstract: A crystal of a compound represented by the general formula (I) or a pharmacologically acceptable salt thereof has an excellent LCAT-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, or renal disease, particularly, an anti-arteriosclerotic agent, wherein R1 is a hydrogen atom or a hydroxy group, and R is a 2-(trifluoromethyl)pyrimidin-5-yl group or a 5-(trifluoromethyl)pyrazin-2-yl group.Type: ApplicationFiled: June 10, 2016Publication date: June 21, 2018Applicant: Daiichi Sankyo Company, LimitedInventors: Katsuhiro Kobayashi, Toshio Kaneko
-
Patent number: 9796709Abstract: A compound represented by the general formula (I) or a pharmacologically acceptable salt thereof has an excellent LCAT-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, hyper-LDL-cholesterolemia, or renal disease, particularly, an anti-arteriosclerotic agent, wherein R is an optionally substituted aryl group or an optionally substituted heteroaryl group, and R1 is a hydrogen atom or a hydroxy group.Type: GrantFiled: December 12, 2014Date of Patent: October 24, 2017Assignee: Daiichi Sankyo Company, LimitedInventors: Hideki Kobayashi, Masami Arai, Toshio Kaneko, Naoki Terasaka
-
Patent number: 9551327Abstract: A power generation switch apparatus including multiple switch keys, a power generation apparatus that is driven to perform power generation by an operation force applied to the multiple switch keys, multiple switches being supplied with an electric power generated by the power generation apparatus and performing a switching movement by an operation of the multiple switch keys, and a switch signal transmission circuit being driven by the electric power from the power generation apparatus and outputting multiple switch signals that are different from each other in correspondence with the switching movement of the multiple switches.Type: GrantFiled: March 22, 2013Date of Patent: January 24, 2017Assignees: MITSUMI ELECTRIC CO., LTD., Honda Access Corp.Inventors: Toshio Kaneko, Nobutaka Tsuneyoshi, Hidetaka Umeoka
-
Publication number: 20160376267Abstract: A compound represented by the general formula (I) or a pharmacologically acceptable salt thereof has an excellent LCAT-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, hyper-LDL-cholesterolemia, or renal disease, particularly, an anti-arteriosclerotic agent, wherein R is an optionally substituted aryl group or an optionally substituted heteroaryl group, and R1 is a hydrogen atom or a hydroxy group.Type: ApplicationFiled: December 12, 2014Publication date: December 29, 2016Applicant: Daiichi Sankyo Company, LimitedInventors: Hideki Kobayashi, Masami Arai, Toshio Kaneko, Naoki Terasaka
-
Patent number: 9150575Abstract: A compound represented by the general formula (I) or a pharmacologically acceptable salt thereof has an excellent LCAT-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, or renal disease, particularly, an anti-arteriosclerotic agent, wherein R is an optionally substituted aryl group or an optionally substituted heteroaryl group.Type: GrantFiled: December 10, 2014Date of Patent: October 6, 2015Assignee: Daiichi Sankyo Company, LimitedInventors: Hideki Kobayashi, Nobuyuki Ohkawa, Daisuke Takano, Hideki Kubota, Toshio Onoda, Toshio Kaneko, Masami Arai, Naoki Terasaka
-
Publication number: 20150152102Abstract: A compound represented by the general formula (I) or a pharmacologically acceptable salt thereof has an excellent LCAT-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, or renal disease, particularly, an anti-arteriosclerotic agent, wherein R is an optionally substituted aryl group or an optionally substituted heteroaryl group.Type: ApplicationFiled: December 10, 2014Publication date: June 4, 2015Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Hideki Kobayashi, Nobuyuki Ohkawa, Daisuke Takano, Hideki Kubota, Toshio Onoda, Toshio Kaneko, Masami Arai, Naoki Terasaka
-
Patent number: 9041231Abstract: A power generation apparatus includes an operation member that has a first operation part or a second operation part operated upon power generation; a power generation part that generates an induced electromotive force upon being driven by a slide member that moves in a first direction or a second direction; first and second elastic units that accumulate an elastic force; a first connection release mechanism that prompts the first elastic unit to accumulate elastic force when the first operation part is operated and allows the elastic force to be output to move the slide member in the second direction when accumulation is completed; and a second connection release mechanism that prompts the second elastic unit to accumulate the elastic force when the second operation part is operated and allows the elastic force to be output to move the slide member in the first direction when accumulation is completed.Type: GrantFiled: January 11, 2012Date of Patent: May 26, 2015Assignee: MITSUMI ELECTRIC CO., LTD.Inventors: Toshio Kaneko, Nobutaka Tsuneyoshi
-
Publication number: 20150054289Abstract: A power generation switch apparatus including multiple switch keys, a power generation apparatus that is driven to perform power generation by an operation force applied to the multiple switch keys, multiple switches being supplied with an electric power generated by the power generation apparatus and performing a switching movement by an operation of the multiple switch keys, and a switch signal transmission circuit being driven by the electric power from the power generation apparatus and outputting multiple switch signals that are different from each other in correspondence with the switching movement of the multiple switches.Type: ApplicationFiled: March 22, 2013Publication date: February 26, 2015Inventors: Toshio Kaneko, Nobutaka Tsuneyoshi, Hidetaka Umeoka
-
Publication number: 20130270092Abstract: A power generation apparatus includes an operation member that has a first operation part or a second operation part operated upon power generation; a power generation part that generates an induced electromotive force upon being driven by a slide member that moves in a first direction or a second direction; first and second elastic units that accumulate an elastic force; a first connection release mechanism that prompts the first elastic unit to accumulate elastic force when the first operation part is operated and allows the elastic force to be output to move the slide member in the second direction when accumulation is completed; and a second connection release mechanism that prompts the second elastic unit to accumulate the elastic force when the second operation part is operated and allows the elastic force to be output to move the slide member in the first direction when accumulation is completed.Type: ApplicationFiled: January 11, 2012Publication date: October 17, 2013Applicant: MITSUMI ELECTRIC CO., LTDInventors: Toshio Kaneko, Nobutaka Tsuneyoshi
-
Patent number: 8497397Abstract: A pharmaceutical composition comprising a compound having Formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein, R1 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; R2 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; and X is, for example, a hydroxyl group or a C1-C6 alkoxy group].Type: GrantFiled: February 24, 2012Date of Patent: July 30, 2013Assignee: Daiichi Sankyo Company, LimitedInventors: Kazumasa Aoki, Koji Suda, Toshio Kaneko, Tomio Kimura
-
Publication number: 20120220593Abstract: A pharmaceutical composition comprising a compound having Formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein, R1 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; R2 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; and X is, for example, a hydroxyl group or a C1-C6 alkoxy group].Type: ApplicationFiled: February 24, 2012Publication date: August 30, 2012Applicant: Daiichi Sankyo Company, LimitedInventors: Kazumasa Aoki, Koji Suda, Toshio Kaneko, Tomio Kimura
-
Patent number: 8232287Abstract: It is intended to provide a pyrimidyl indoline compound which structurally differs from compounds used as active ingredients in conventional oral hypoglycemic agents and has excellent hypoglycemic effect.Type: GrantFiled: October 15, 2008Date of Patent: July 31, 2012Assignee: Daiichi Sankyo Company, LimitedInventors: Toshio Kaneko, Takeshi Shida, Takayuki Baba, Koji Matsumoto, Kazumasa Aoki
-
Patent number: 8143446Abstract: A pharmaceutical composition comprising a compound having Formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein, R1 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; R2 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; and X is, for example, a hydroxyl group or a C1-C6 alkoxy group].Type: GrantFiled: May 11, 2006Date of Patent: March 27, 2012Assignee: Daiichi Sankyo Company, LimitedInventors: Kazumasa Aoki, Koji Suda, Toshio Kaneko, Tomio Kimura
-
Publication number: 20100292259Abstract: It is intended to provide a pyrimidyl indoline compound which structurally differs from compounds used as active ingredients in conventional oral hypoglycemic agents and has excellent hypoglycemic effect.Type: ApplicationFiled: October 15, 2008Publication date: November 18, 2010Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Toshio Kaneko, Takeshi Shida, Takayuki Baba, Koji Matsumoto, Kazumasa Aoki
-
Patent number: 7629494Abstract: A process for producing a cyclopropylphenol represented by of formula (10): wherein R1, R2, R3 and R4 each may represent a hydrogen; Z represents a hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or phenyl; and Y1, Y2 and Y3 each may represent a hydrogen; by reacting a compound of formula (7): wherein X represents a halogen; and V represents a hydrogen or —W—R5, with a metal, metal salt or organometallic compound of formula (8): M2 to obtain a compound of formula (9): and obtaining a compound of formula (10) by hydrolysis in the case wherein V represents —W—R5, wherein W is CO, SO or SO2 and R5 is alkyl, haloalkyl, cycloalkyl, alkenyl, alkynyl, phenyl, alkoxy or haloalkoxy.Type: GrantFiled: March 31, 2006Date of Patent: December 8, 2009Assignee: Mitsui Chemicals Agro, Inc.Inventors: Yoshihisa Tsukamoto, Hiroyuki Komai, Toshio Kaneko, Takeshi Takada
-
Publication number: 20090266714Abstract: The present invention is to provide a method for forming a multi-layer coating film, which can combine a pre-treating step conducted for a metal substrate, before electrodeposition coating, and an electrodeposition coating step. The method comprises: a step of dipping a material to be coated in an aqueous coating composition comprising (A) a rare earth metal compound, (B) a base resin having a cationic group, and (C) a curing agent, wherein a content of the rare earth metal compound (A) in the aqueous coating composition is limited to specific range; a pre-treating step of applying a voltage of less than 50 V in the aqueous coating composition, wherein the material to be coated is used as a cathode; and an electrodeposition coating of applying a voltage of 50 to 450 V in the aqueous coating composition, wherein the material to be coated is used as a cathode.Type: ApplicationFiled: April 7, 2006Publication date: October 29, 2009Inventors: Toshio Kaneko, Satoshi Okamoto, Masanobu Futsuhara, Makoto Doi, Eisaku Okada, Takehiro Nito
-
Publication number: 20090208716Abstract: The present invention relates to a composite chemical conversion coating film containing a crystalline continuous coating film that is formed on a metal substrate. The present invention also relates to a process for forming a multiple layered coating film including (A) the first step of immersing an untreated metal substrate in an aqueous solution containing nitrate of a rare earth metal and forming a crystalline continuous coating film containing a rare earth metal compound with a deposition amount of 1 mg/m2 at lower limit and 110 mg/m2 at upper limit by cathode electrolysis and (B) the second step of coating an electrodeposition coating composition containing an organic acid or inorganic acid salt of a rare earth metal by cathode electrodeposition.Type: ApplicationFiled: March 5, 2007Publication date: August 20, 2009Inventors: Toshio Kaneko, Satoshi Okamoto, Masanobu Futsuhara, Makoto Doi, Eisaku Okada
-
Publication number: 20090118199Abstract: A pharmaceutical composition comprising a compound having Formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein, R1 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; R2 is, for example, a C6-C10 aryl group which may be substituted with one group or more than one group selected from substituent group ?; and X is, for example, a hydroxyl group or a C1-C6 alkoxy group].Type: ApplicationFiled: May 11, 2006Publication date: May 7, 2009Applicant: Daiichi Sankyo Company , LimitedInventors: Kazumasa Aoki, Koji Suda, Toshio Kaneko, Tomio Kimura
-
Publication number: 20090054681Abstract: A process for producing a cyclopropylphenol represented by of formula (10): wherein R1, R2, R3 and R4 each may represent a hydrogen; Z represents a hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or phenyl; and Y1, Y2 and Y3 each may represent a hydrogen; by reacting a compound of formula (7): wherein X represents a halogen; and V represents a hydrogen or —W—R5, with a metal, metal salt or organometallic compound of formula (8): M2 to obtain a compound of formula (9): and obtaining a compound represented by general of formula (10) by hydrolysis in the case wherein V represents —W—R5, wherein W is CO, SO or SO2 and R5 is alkyl, haloalkyl, cycloalkyl, alkenyl, alkynyl, phenyl, alkoxy or haloalkoxy.Type: ApplicationFiled: March 31, 2006Publication date: February 26, 2009Applicant: SANKYO AGRO COMPANY, LIMITEDInventors: Yoshihisa Tsukamoto, Hiroyuki Komai, Toshio Kaneko, Takeshi Takada