Patents by Inventor Toshio Nishiyama

Toshio Nishiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110236513
    Abstract: The invention provides cosmetics or dermatological compositions comprising plant extract or whey extract having an action to potentiate laminin 5 productivity in the epidermal cells. They have mainly the action and efficacy to prevent or improve aging in the skin.
    Type: Application
    Filed: May 10, 2011
    Publication date: September 29, 2011
    Inventors: Keiko TAKADA, Satoshi Amano, Toshio Nishiyama
  • Publication number: 20070254052
    Abstract: The invention provides cosmetics or dermatological compositions comprising plant extract or whey extract having an action to potentiate laminin 5 productivity in the epidermal cells. They have mainly the action and efficacy to prevent or improve aging in the skin.
    Type: Application
    Filed: June 29, 2007
    Publication date: November 1, 2007
    Inventors: Keiko Takada, Satoshi Amano, Toshio Nishiyama
  • Publication number: 20040202638
    Abstract: The invention provides cosmetics or dermatological compositions comprising plant extract or whey extract having an action to potentiate laminin 5 productivity in the epidermal cells. They have mainly the action and efficacy to prevent or improve aging in the skin.
    Type: Application
    Filed: February 20, 2004
    Publication date: October 14, 2004
    Inventors: Keiko Takada, Satoshi Amano, Toshio Nishiyama
  • Patent number: 6689936
    Abstract: The invention provides methods of evaluating a treatment for its effect on skin. The invention also provides non-human transgenic animals, e.g., mice, having a reporter gene coupled to a skin-metabolism promoter.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: February 10, 2004
    Assignee: The General Hospital Corp.
    Inventors: Robert Burgeson, Satoshi Amano, Jiro Kishimoto, Toshio Nishiyama, Ritsuko Ehama
  • Patent number: 6544966
    Abstract: Disclosed are compositions for promoting the production of laminin 5 in epidermic cells which contain a lysophospholipid having a C14-22 fatty acid residue or a preparation derived from soybeans as an active ingredient and which can be used in the fields of cosmetics and dermatology. These compositions may be used especially for the purpose of potentiating the skin.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: April 8, 2003
    Assignee: Shiseido Company, Ltd.
    Inventors: Satoshi Amano, Toshio Nishiyama
  • Patent number: 6153593
    Abstract: The use of laminin-5 to promote formation of basement membrane and to form skin equivalents and to improve grafting of keratinocyte sheets.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: November 28, 2000
    Assignees: The General Hospital Corporation, Shiseido Co., Ltd., University School of Medicine
    Inventors: Robert E. Burgeson, Makoto Tsunenaga, Satoshi Amano, Toshio Nishiyama, Eijiro Adachi, Nobuyuji Shioya
  • Patent number: 5137875
    Abstract: A hyaluronic acid-containing aqueous solution or aqueous dispersion of collagen having a pH of from about 6.5 to about 8.0 and an osmolality of from about 230 to about 320 mOsm/kgH.sub.2 O. The aqueous solution or the aqueous dispersion of collagen is useful as an agent for correction and reparation of a depressed part of or a void in soft tissue of mammals.
    Type: Grant
    Filed: April 18, 1989
    Date of Patent: August 11, 1992
    Assignees: Shiseido Co., Ltd., Koken Co., Ltd.
    Inventors: Makoto Tsunenaga, Naoki Tominaga, Toshio Nishiyama, Toru Yamashita, Mutsumi Fukuyama, Teruo Miyata, Masayasu Furuse
  • Patent number: 5082509
    Abstract: A method of producing an oriented electrical steel sheet having superior magnetic properties comprises the steps of, hot rolling a slab containing 0.8 to 6.8% of Si, 0.008% of Al acid soluble, the balance being Fe and accompanying impurities, by weight to form a strip, cold rolling the strip, primary-recrystallization annealing, coating the strip with an annealing separator, and finishing annealing, a nitriding treatment being effected after the primary recrystallization annealing but before the start of the secondary recrystallization of the finishing annealing. According to the present invention, with an atmosphere oxidizing degree (PH.sub.2 O/PH.sub.2): x in a soaking process in said primary recrystallization annealing an annealing is effected in an atmosphere which has an oxidizing degree (PH.sub.2 O/PH.sub.2): y in a range defined by the following inequality, at a temperature ranging from 650.degree. to 800.degree. C. in the heating process, for at least 5 secs.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: January 21, 1992
    Assignee: Nippon Steel Corporation
    Inventors: Yoshiyuki Ushigami, Toyohiko Konno, Yozo Suga, Kiyoshi Ueno, Mikio Itoh, Toshio Nishiyama, Kenichi Takimoto
  • Patent number: 4799418
    Abstract: Disclosed is a pressure actuator such as a vacuum actuator comprising a valve unit including a plurality of solenoid valves and a diaphragm unit including a diaphragm defining a pressure chamber, air pressure within the pressure chamber being adjusted by selective activation of the solenoid valves which communicate the pressure chamber with pressure sources of different pressure levels, in which a casing of the actuator defines an accommodating chamber for accommodating the solenoid valve unit and a wall surface of the chamber is provided with ribs for guiding and positioning the solenoid valve unit inside the chamber. The ribs may be adapted to make a sliding contact with a side surface of the yokes of the solenoid valves and a smooth surface a printed circuit board which is attached to the solenoid valve unit. Alternatively or additionally, the ribs may be adapted to be fitted into a gap between a pair of adjacent yokes of the solenoid valves.
    Type: Grant
    Filed: August 21, 1987
    Date of Patent: January 24, 1989
    Assignee: Mitsuba Electric Mfg. Co., Ltd.
    Inventors: Yoshikazu Takahashi, Toshio Nishiyama
  • Patent number: 4756233
    Abstract: Disclosed is an air filter unit for a pressure actuator such as a vacuum actuator for a speed control of an automobile comprising a solenoid valve unit including a plurality of solenoid valves and a diaphragm unit including a diaphragm defining a pressure chamber, air pressure within the pressure chamber being adjusted by selective activation of the solenoid valves which communicate the pressure chamber with pressure sources of different pressure levels. A filter element holder defining a pair of receptacles for receiving filter elements therein is attached to the solenoid valve unit so as to intercept air flow from an external air source into the vacuum chamber by way of the solenoid valves. The filter element for a vent valve which is frequently used is finer in structure than that for a safety valve which is less frequently used and is required to be capable of rapid introduction of air into the vacuum chamber.
    Type: Grant
    Filed: August 21, 1987
    Date of Patent: July 12, 1988
    Assignee: Mitsuba Electric Mfg. Co., Ltd.
    Inventors: Yoshikazu Takahashi, Toshio Nishiyama
  • Patent number: 4713397
    Abstract: A composition for reducing hair fall-out comprising a ubiquinone (coenzyme Q.sub.n) represented by the general formula: ##STR1## wherein n represents an integer of from 7 to 10. In addition to such a ubiquinone, the composition may contain a skin peripheral vasodilator drug, such as carpronium chloride, vitamin E nicotinate and benzyl nicotinate.
    Type: Grant
    Filed: August 26, 1985
    Date of Patent: December 15, 1987
    Assignee: Eisai Co., Ltd.
    Inventors: Shinichi Hirama, Toshio Nishiyama, Youichi Ohta, Makoto Uzuka, Kenichi Tomita, Keisuke Nakajima, Kazumaro Furuse