Abstract: [Problem] COVID-19 caused by coronavirus SARS-CoV-2, cytokine release syndrome, cytokine release syndrome with CAR (chimeric antigen receptor)-T therapy, sepsis, systemic inflammatory response syndrome, hemophagocytic syndrome, macrophage activation syndrome, influenza, GVHD, systemic vasculitis, Kawasaki disease, Takayasu arteritis, and other diseases, if severe, can cause acute respiratory distress syndrome, disseminated intravascular coagulation syndrome, acute circulatory insufficiency, multi-organ failure, and other symptoms which are one of the causes of death. [Solution to Problem] Compounds represented by formulas (1) to (4) are effective when taken orally and can be expressed in smaller amounts than mangiferin.

Abstract: Disclosed is an air conditioner of the present invention comprises a refrigeration cycle using a refrigerant compressor, a four-way valve, an external heat exchanger, an expansion device, and an internal heat exchanger in such a manner that these components are separately mounted in an external unit and an internal unit, wherein the external heat exchanger is mounted on the external unit; the internal heat exchange is mounted in the internal unit; both of the heat exchangers mounted in the units are connected to each other by means of a refrigerant piping to form the refrigeration cycle; and a control means is provided for changing the expansion amount of the expansion device according to the length of the refrigerant piping thereby adjusting the high-low pressure difference in the refrigeration cycle.