Abstract: The invention provides a method for producing radiolabeled tyrosine derivatives with good purity and stability, by a safe method suitable for industrial production of pharmaceuticals. The invention relates to a method for producing Compound (5) and Radiolabeled Compound (6) as follows: wherein each symbol is as defined in the description.

Abstract: An injection molding machine includes an injection apparatus configured to perform an injection operation of a material and a mold clamping apparatus configured to mold the material injected from the injection apparatus. Here, the injection apparatus includes a screw, a piston connected to the screw, and a hydraulic apparatus configured to drive the piston in an axial direction. On the other hand, the mold clamping apparatus includes a movable platen to which a first mold can be attached, a fixed platen to which a second mold can be attached, and an electric drive unit configured to move the movable platen in a mold closing direction or a mold opening direction with respect to the fixed platen.

Abstract: An injection apparatus of one embodiment includes a cylinder, a screw, and a drive mechanism configured to drive the screw. The drive mechanism includes a piston having a hollow piston rod, a connection rod having one end side inserted into the piston rod, the connection rod being rotatable with respect to the piston and movable integrally with the piston in a direction of a central axis of the piston rod, and a rotating body which is arranged around the connection rod and is driven to rotate around a central axis of the connection rod as a rotation axis. A plurality of external teeth are provided on the connection rod, and a plurality of internal teeth meshing with the external teeth are provided on the rotating body. Also, the screw is non-rotatably connected to the other end side of the connection rod protruding from the piston rod.

Abstract: A configuration of oil hydraulic power unit is simplified. In the oil hydraulic power unit, a port B and a port C are communicated to each other. By this, the hydraulic oil supplied to the port B can also be supplied to the port C even in exclusion of the solenoid valve and the flow-rate control valve, and, as a result, the hydraulic oil supplied to the port C contacts a side surface of the piston, and therefore, a backward pressure can be applied to the side surface of the piston. Thus, according to the oil hydraulic power unit, the backward movement of the piston can be achieved even in the exclusion of the solenoid valve and the flow-rate control valve.

Abstract: An injection apparatus of one embodiment includes a cylinder, a screw provided inside the cylinder, and a drive mechanism configured to rotate the screw, move the screw forward, and move the screw backward. The drive mechanism includes a piston having a piston rod and a rotating body which is arranged around the piston rod and is driven to rotate around a central axis of the piston rod as a rotation axis. A plurality of external teeth extending in the direction of the central axis of the piston rod are provided on the piston rod, and a plurality of internal teeth meshing with the external teeth are provided on the rotating body. Also, the screw is non-rotatably connected to a distal end side of the piston rod.

Abstract: Performance of an injection molding machine is improved. The injection molding machine includes: a central controller centrally controlling an injection molding operation; a first injection apparatus performing an injecting operation of material, based on a first injection start signal output from the central controller; a second injection apparatus performing an injecting operation of material, based on a second injection start signal output from the central controller; and a mold clamping apparatus performing a mold clamping apparatus. The injection molding machine is configured to adjust a time difference between a first injection start timing of the material injected from the first injection apparatus and a second injection start timing of the material injected from the second injection apparatus.

Abstract: An injection device includes: a heating cylinder; a screw disposed in the heating cylinder; and a pair of piston cylinder components disposed on two sides of the heating cylinder. The pair of piston cylinder components are installed so that one end portion of each of the pair of piston cylinder components is connected to a mold clamping device, and the heating cylinder and the screw are integrally driven in a direction close to or away from the mold clamping device by expansion and contraction of the pair of piston cylinder components. One of the pair of piston cylinder components is provided with a stop mechanism configured to stop expansion and contraction of the piston cylinder component.

Abstract: An injection device includes: a heating cylinder; a screw disposed in the heating cylinder; and a pair of piston cylinder components disposed on two sides of the heating cylinder. The pair of piston cylinder components are installed so that one end portion of each of the pair of piston cylinder components is connected to a mold clamping device, and the heating cylinder and the screw are integrally driven in a direction close to or away from the mold clamping device by expansion and contraction of the pair of piston cylinder components. One of the pair of piston cylinder components is provided with a stop mechanism configured to stop expansion and contraction of the piston cylinder component.

Abstract: A twin injection molding machine includes: a mold clamping device configured to clamp a mold; and first and second injection devices each including: a heating cylinder; a screw disposed in the heating cylinder; and a screw driving device including driving system components and configured to drive the screw. The first and second injection devices are disposed symmetrically with respect to a machine center line of the mold clamping device. The driving system components provided in the screw driving device of the first injection device and the driving system components provided in the screw driving device of the second injection device are each disposed on a side away from the machine center line in the respective screw driving devices.

Abstract: A flange is formed on a heating cylinder in a vicinity of a center in a longitudinal direction and a predetermined joining plate adheres to the flange. A flange plate is provided on a support frame. The joining plate is fixed to the flange plate to attach and detach freely, and the heating cylinder is caused to be supported by the support frame. Accordingly, movement in an axial direction and rotation of the heating cylinder are restricted. A guide portion for positioning during attachment and detachment is provided on one or both of the joining plate and the flange plate.

Abstract: A screw can be driven along an axial direction of a heating barrel and rotatable. An injection piston drives the screw along the axial direction. An injection hydraulic cylinder is partitioned into a first chamber in which pressured hydraulic oil for driving the injection piston is supplied and a second chamber from which hydraulic oil is discharged, and drives the injection piston in the axial direction by hydraulic pressure. A first oil discharge port is blocked by the injection piston when the injection piston advances to a holding pressure switching position. A second oil discharge port can discharge the hydraulic oil from the front chamber regardless of the position of the injection piston. The first oil discharge port is disposed at a position opposed to the first oil discharge port across a center axis of the injection hydraulic cylinder, and is connected to the first oil discharge port.

Abstract: A flange is formed on a heating cylinder in a vicinity of a center in a longitudinal direction and a predetermined joining plate adheres to the flange. A flange plate is provided on a support frame. The joining plate is fixed to the flange plate to attach and detach freely, and the heating cylinder is caused to be supported by the support frame. Accordingly, movement in an axial direction and rotation of the heating cylinder are restricted. A guide portion for positioning during attachment and detachment is provided on one or both of the joining plate and the flange plate.