Abstract: The invention provides a method for producing radiolabeled tyrosine derivatives with good purity and stability, by a safe method suitable for industrial production of pharmaceuticals. The invention relates to a method for producing Compound (5) and Radiolabeled Compound (6) as follows: wherein each symbol is as defined in the description.

Abstract: A screw rotor lead correction calculation device includes an initial data input section configured to input an error as a distance with respect to a reference lead at each axial position of a rotor groove portion of a screw rotor, and a processing machine input correction amount/position output section configured to compute and output, based on the error as the distance input to the initial data input section, a lead correction amount with respect to the reference lead and a lead correction starting position as an axial position for starting lead correction. With this configuration, correction data for obtaining a screw rotor with a high-accuracy lead can be obtained from a lead error with respect to a reference lead in a screw rotor obtained by ground finish of the material of the screw rotor.

Abstract: A device includes a charge pump configured to provide a current to a bootstrap capacitor responsive to a charge pump switch being closed. The device also includes a current limiter coupled in series between the charge pump switch and the charge pump. The current limiter is configured to receive a control signal from a controller that indicates whether the device is to operate in a first mode or in a second mode; responsive to the control signal indicating the first mode, allow a first value of current to the charge pump switch; and, responsive to the control signal indicating the second mode, limit the current to the charge pump switch to a second value. The second value is less than the first value.

Abstract: An example apparatus includes a level shifter having a first supply input, a gate driver having a second supply input coupled to the first supply input and adapted to be coupled to a cathode of a diode, the gate driver having an output adapted to be coupled to a control terminal of a switch, and a current source circuit having an input and an output, the input adapted to be coupled to a power supply and the output adapted to be coupled to the first supply input, the second supply input and to a capacitor.

Abstract: A system includes a level shifter coupled to a voltage source, a first transistor, and a second transistor. The system also includes a first current source coupled to the first transistor and the second transistor and configured to bias the first transistor and the second transistor. The system includes a slew detector coupled to the voltage source and to the first current source, where the slew detector is configured to detect a change in voltage of the voltage source, and further configured to provide current to the first current source responsive to detecting the change. The system also includes a second current source coupled in parallel to the first current source, where the second current source is configured to provide current to the first current source responsive to a control signal.

Abstract: A device includes a charge pump configured to provide a current to a bootstrap capacitor responsive to a charge pump switch being closed. The device also includes a current limiter coupled in series between the charge pump switch and the charge pump. The current limiter is configured to receive a control signal from a controller that indicates whether the device is to operate in a first mode or in a second mode; responsive to the control signal indicating the first mode, allow a first value of current to the charge pump switch; and, responsive to the control signal indicating the second mode, limit the current to the charge pump switch to a second value. The second value is less than the first value.

Abstract: A system includes a level shifter coupled to a voltage source, a first transistor, and a second transistor. The system also includes a first current source coupled to the first transistor and the second transistor and configured to bias the first transistor and the second transistor. The system includes a slew detector coupled to the voltage source and to the first current source, where the slew detector is configured to detect a change in voltage of the voltage source, and further configured to provide current to the first current source responsive to detecting the change. The system also includes a second current source coupled in parallel to the first current source, where the second current source is configured to provide current to the first current source responsive to a control signal.

Abstract: An example apparatus includes a level shifter having a first supply input, a gate driver having a second supply input coupled to the first supply input and adapted to be coupled to a cathode of a diode, the gate driver having an output adapted to be coupled to a control terminal of a switch, and a current source circuit having an input and an output, the input adapted to be coupled to a power supply and the output adapted to be coupled to the first supply input, the second supply input and to a capacitor.

Abstract: A gate driver circuit includes a comparator and a gate driver. The comparator is configured to detect a short circuit in a first power field effect transistor (FET). The gate driver is configured to drive a gate of the first power FET by generating a first signal at a first drive current. In response to the comparator detecting a short circuit in the first power FET, the gate driver is further configured to pulse the first signal at a first pulldown current. After the pulse has ended, the gate driver is further configured to drive the gate of the first power FET at a first hold current. The first hold current is less than the first pulldown current.

Abstract: A screw rotor lead correction calculation device includes an initial data input section configured to input an error as a distance with respect to a reference lead at each axial position of a rotor groove portion of a screw rotor, and a processing machine input correction amount/position output section configured to compute and output, based on the error as the distance input to the initial data input section, a lead correction amount with respect to the reference lead and a lead correction starting position as an axial position for starting lead correction. With this configuration, correction data for obtaining a screw rotor with a high-accuracy lead can be obtained from a lead error with respect to a reference lead in a screw rotor obtained by ground finish of the material of the screw rotor.

Abstract: A voltage regulator includes an output transistor, an error amplifier coupled to the output transistor, a cascode transistor coupled to the output transistor in series, and a cascode bias circuit coupled to the cascode transistor and the output transistor. The output transistor is configured to generate an output signal at a first voltage. The error amplifier is configured to receive a reference signal. The cascode bias circuit is configured to bias the cascode transistor such that, in response to a drain-to-source short circuit of the output transistor, the cascode transistor generates the output signal at the first voltage.

Abstract: An apparatus includes a control circuit that includes a configuration register and configured to receive a configuration setting across an external bus. The configuration setting encodes a first voltage state for the apparatus. The control circuit includes an input configured to be coupled to an external electrical device. The control circuit is configured to determine a value of the external device that maps to a second voltage state for the apparatus. The control logic is configured to transition the apparatus to a safe mode upon a determination that the first voltage state does not match the second voltage state.

Abstract: A gate driver circuit includes a comparator and a gate driver. The comparator is configured to detect a short circuit in a first power field effect transistor (FET). The gate driver is configured to drive a gate of the first power FET by generating a first signal at a first drive current. In response to the comparator detecting a short circuit in the first power FET, the gate driver is further configured to pulse the first signal at a first pulldown current. After the pulse has ended, the gate driver is further configured to drive the gate of the first power FET at a first hold current. The first hold current is less than the first pulldown current.

Abstract: A voltage regulator includes an output transistor, an error amplifier coupled to the output transistor, a cascode transistor coupled to the output transistor in series, and a cascode bias circuit coupled to the cascode transistor and the output transistor. The output transistor is configured to generate an output signal at a first voltage. The error amplifier is configured to receive a reference signal. The cascode bias circuit is configured to bias the cascode transistor such that, in response to a drain-to-source short circuit of the output transistor, the cascode transistor generates the output signal at the first voltage.

Abstract: An apparatus includes a control circuit that includes a configuration register and configured to receive a configuration setting across an external bus. The configuration setting encodes a first voltage state for the apparatus. The control circuit includes an input configured to be coupled to an external electrical device. The control circuit is configured to determine a value of the external device that maps to a second voltage state for the apparatus. The control logic is configured to transition the apparatus to a safe mode upon a determination that the first voltage state does not match the second voltage state.

Abstract: The table on which a workpiece is put can travel on a guide rail mechanism relative to a working head with a cutting tool mounted thereon. The table is connected through a nut to a ball screw part to move in an axial direction thereof as the ball screw part rotates. One end of the ball screw part is supported by a bearing and the other end is connected to a servomotor to be rotationally driven. A hollow part is provided in the table to receive therein a damper mechanism part, which comprises a spring, a damper, and a weight, the table and the weight being arranged to enable traveling separately on guide rails. Thereby, even when the workpiece is heavy, the weight can move relative to the table to effectively damp vibrations of the table in a feed direction.

Abstract: The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, a process for preparation thereof, a pharmaceutical composition comprising the same, and a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.

Abstract: The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.

Abstract: Disclosed is a phosphazene compound and a photosensitive resin composition. The phosphazene compound is obtained by reacting a phenoxyphosphazene compound (A-1) having a phenolic hydroxyl group and/or a cross-linked phenoxyphosphazene compound (A-2) obtained by cross-linking the phenoxyphosphazene compound (A-1) with an epoxy compound (B) having an unsaturated double bond and/or an isocyanate compound (C), wherein the phosphazene compound has an unsaturated double bond in its molecule.

Abstract: The table on which a workpiece is put can travel on a guide rail mechanism relative to a working head with a cutting tool mounted thereon. The table is connected through a nut to a ball screw part to move in an axial direction thereof as the ball screw part rotates. One end of the ball screw part is supported by a bearing and the other end is connected to a servomotor to be rotationally driven. A hollow part is provided in the table to receive therein a damper mechanism part, which comprises a spring, a damper, and a weight, the table and the weight being arranged to enable traveling separately on guide rails. Thereby, even when the workpiece is heavy, the weight can move relative to the table to effectively damp vibrations of the table in a feed direction.