Patents by Inventor Toshiro Majima

Toshiro Majima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6586633
    Abstract: The present invention relates to amine derivatives represented by formula (1) or salts thereof. R3 represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1 to 4.) Exhibiting excellent antifungal effect, these compounds are highly useful as antifungal agents, antifungal compositions, drugs, etc.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: July 1, 2003
    Assignee: Pola Chemical Industries, Inc.
    Inventors: Masayuki Yuasa, Yukio Kawazu, Toshimitsu Suzuki, Toshiro Majima, Takao Itoh, Takuji Nakashima, Akira Nozawa, Hiroyuki Takimoto, Kouji Yokoyama
  • Patent number: 6475748
    Abstract: Disclosed is a method for differentiating human peripheral blood granulocytes which comprises cultivating the granulocytes in the presence of an interferon and acting an immune complex on said granulocytes in the presence of a chemiluminescent substance, and measuring the chemiluminescent amounts induced. It contributes to the screening of patients suffering from serious infectious diseases or a range of inflammations, and is advantageous for monitoring the curative effects for those patients.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: November 5, 2002
    Assignee: Pola Chemical Industries, Inc.
    Inventors: Toshiro Majima, Ryoichi Nagatomi, Tasuke Konno, Toshikazu Awataguchi, Yoshimi Yano
  • Patent number: 6329399
    Abstract: Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. [in the formula (1, R1 represents a C1-5 alkyl group which may be halogenated, R2 represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-phenylethyl)benzyl group, 1-or 2-naphthylmethyl group, or a hydrocarbon group having 3,3-dimethyl-1-butynyl group or a phenyl group at its terminal and 1 to 3 double bonds; R3 represents oxygen atom or a methylene group which may be substituted by a C1-4 alkyl group; and R4 represents 1-or 2 naphthyl group or a phenyl group which may be substituted.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: December 11, 2001
    Assignee: Pola Chemical Industries, Inc.
    Inventors: Takao Itoh, Takuji Nakashima, Akira Nozawa, Kouji Yokoyama, Hiroyuki Takimoto, Masayuki Yuasa, Yukio Kawazu, Toshimitsu Suzuki, Toshiro Majima
  • Patent number: 6136863
    Abstract: This invention relates to compounds represented by the following formula (1): ##STR1## wherein R.sup.1 represents a substituted or unsubstituted phenyl group, R.sup.2 represents a substituted or unsubstituted phenylene group, R.sup.3 represents a substituted or unsubstituted phenyl group or an aliphatic hydrocarbon group containing at least four .pi. electrons, R.sup.4 represents an alkyl group having 1 to 4 carbon atoms, and m and n individually represent integers of from 1 to 4, or salts thereof, and also to compositions containing the same. These compounds have antifungal activities and are useful as drugs.
    Type: Grant
    Filed: August 7, 1998
    Date of Patent: October 24, 2000
    Assignee: Pola Chemical Industries, Inc.
    Inventors: Yukio Kawazu, Masayuki Yuasa, Toshimitsu Suzuki, Takuji Nakashima, Takao Itoh, Toshiro Majima
  • Patent number: 6015925
    Abstract: This invention relates to compounds represented by the following formula (1): ##STR1## wherein R.sup.1 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 18 carbon atoms, R.sup.2 represents a hydrogen atom or a substituted or unsubstituted aromatic hydrocarbon group having 6 to 18 carbon atoms, R.sup.3 represents an alkyl group having 1 to 4 carbon atoms, R.sup.4 represents a substituted or unsubstituted phenyl group or an aliphatic hydrocarbon group containing at least four .pi. electrons, and m and n individually represent integers of from 1 to 4, or salts thereof, and also to compositions containing the same. These compounds have antifungal activities and are useful as drugs and the like.
    Type: Grant
    Filed: September 22, 1998
    Date of Patent: January 18, 2000
    Assignee: Pola Chemical Industries, Inc.
    Inventors: Yukio Kawazu, Toshimitsu Suzuki, Masayuki Yuasa, Yuichi Yokomizo, Toshiro Majima, Takao Ito, Takuji Nakashima, Akira Nozawa