Abstract: A heavy-duty pneumatic tire designed to suppress the occurrence of heel-and-toe wear in the shoulder blocks while maintaining good drainage and traction performance through the final stage of the wear life. In this heavy-duty pneumatic tire, whose shoulder portion is divided into a plurality of shoulder blocks in the tire circumferential direction, and wherein the depth of the lug groove between each two adjacent of the shoulder blocks is set to be equal to the depth of main the grooves, a non-contact rib is provided, in a serial configuration in the tire circumferential direction, to a buttress portion outside a ground contact width, so as to come into contact with the side faces of the shoulder blocks in the state that the tire is in contact with the ground with a specified inflation pressure and a specified load.

Abstract: A heavy-duty pneumatic tire designed to suppress the occurrence of heel-and-toe wear in the shoulder blocks while maintaining good drainage and traction performance through the final stage of the wear life. In this heavy-duty pneumatic tire, whose shoulder portion is divided into a plurality of shoulder blocks in the tire circumferential direction, and wherein the depth of the lug groove between each two adjacent of the shoulder blocks is set to be equal to the depth of main the grooves, a non-contact rib is provided, in a serial configuration in the tire circumferential direction, to a buttress portion outside a ground contact width, so as to come into contact with the side faces of the shoulder blocks in the state that the tire is in contact with the ground with a specified inflation pressure and a specified load.

Abstract: A method for the immunoassay of elastase-1 which comprises subjecting elastase-1 to be measured and a labelled antigen elastase-1, both having previously been treated with a synthetic elastase inhibitor, to a competitive reaction with anti-elastase-1 antibody, a kit of reagents for the immunoassay of elastase-1 which comprises a buffer liquid for immunoassay containing a synthetic elastase inhibitor, a labelled antigen elastase-1, a standard antigen elastase-1 and anti-elastase-1 antibody. The method and the kit of reagents for the immunoassay of elastase-1 are effectively utilized for diagnosis of pancreatic diseases, especially acute or chronic pancreatitis and cancer of the pancreas.