Patents by Inventor Toshiya Nishi

Toshiya Nishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200306238
    Abstract: Aspects of the present invention relate to a method of treating an epileptic encephalopathy in a mammal in need thereof, comprising administering a composition comprising an effective amount of (4-benzyl-4-hydroxypiperidin-1-yl) (2,4?-bipyridin-3-yl)methanone or a pharmaceutically acceptable salt thereof to the mammal.
    Type: Application
    Filed: August 30, 2018
    Publication date: October 1, 2020
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Toshiya NISHI, Shinichi KONDO
  • Publication number: 20190071455
    Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: November 19, 2018
    Publication date: March 7, 2019
    Inventors: Tatsuki KOIKE, Masato YOSHIKAWA, Haruhi ANDO, William John FARNABY, Toshiya NISHI
  • Patent number: 10112956
    Abstract: An object of the present invention is to provide a compound having a superior CH24H inhibitory action, which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: October 30, 2018
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki Koike, Yuichi Kajita, Masato Yoshikawa, Shuhei Ikeda, Eiji Kimura, Tomoaki Hasui, Toshiya Nishi, Hiromi Fukuda
  • Publication number: 20170197983
    Abstract: An object of the present invention is to provide a compound having a superior CH24H inhibitory action, which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: March 23, 2017
    Publication date: July 13, 2017
    Inventors: Tatsuki KOIKE, Yuichi KAJITA, Masato YOSHIKAWA, Shuhei IKEDA, Eiji KIMURA, Tomoaki HASUI, Toshiya NISHI, Hiromi FUKUDA
  • Publication number: 20170145031
    Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: February 3, 2017
    Publication date: May 25, 2017
    Inventors: Tatsuki KOIKE, Masato YOSHIKAWA, Haruhi ANDO, William John FARNABY, Toshiya NISHI
  • Patent number: 9624184
    Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: April 18, 2017
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Haruhi Ando, Tomoaki Hasui, Toshiya Nishi
  • Patent number: 9598398
    Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: March 21, 2017
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki Koike, Masato Yoshikawa, Haruhi Ando, William John Farnaby, Shuhei Ikeda, Yuichi Kajita, Toshiya Nishi
  • Patent number: 9586930
    Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: March 7, 2017
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki Koike, Masato Yoshikawa, Haruhi Ando, William John Farnaby, Toshiya Nishi
  • Publication number: 20160326136
    Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: July 28, 2016
    Publication date: November 10, 2016
    Inventors: Tatsuki KOIKE, Masato YOSHIKAWA, Haruhi ANDO, William John FARNABY, Toshiya NISHI
  • Patent number: 9440990
    Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: September 13, 2016
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki Koike, Masato Yoshikawa, Haruhi Ando, William John Farnaby, Toshiya Nishi
  • Publication number: 20160052897
    Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
    Type: Application
    Filed: April 3, 2014
    Publication date: February 25, 2016
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki KOIKE, Masato YOSHIKAWA, Izumi NOMURA, Yoshiteru ITO, Eiji KIMURA, Haruhi ANDO, Tomoaki HASUI, Toshiya NISHI
  • Publication number: 20160024049
    Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
    Type: Application
    Filed: April 3, 2014
    Publication date: January 28, 2016
    Inventors: Tatsuki KOIKE, Masato YOSHIKAWA, Haruhi ANDO, William John FARNABY, Shuhei IKEDA, Yuichi KAJITA, Toshiya NISHI
  • Publication number: 20150376205
    Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: September 8, 2015
    Publication date: December 31, 2015
    Inventors: Tatsuki KOIKE, Masato Yoshikawa, Haruhi Ando, William John Farnaby, Toshiya Nishi
  • Publication number: 20150315209
    Abstract: An object of the present invention is to provide a compound having a superior CH24H inhibitory action, which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: December 10, 2013
    Publication date: November 5, 2015
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki KOIKE, Yuichi KAJITA, Masato YOSHIKAWA, Shuhei IKEDA, Eiji KIMURA, Tomoaki HASUI, Toshiya NISHI, Hiromi FUKUDA
  • Publication number: 20150266872
    Abstract: The present invention provides a compound or a salt thereof useful for an agent for the prophylaxis or treatment of neurodegenerative disease and the like. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
    Type: Application
    Filed: October 15, 2013
    Publication date: September 24, 2015
    Inventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Tomoaki Hasui, Haruhi Ando, Hiromi Fukuda, Toshiya Nishi
  • Publication number: 20090209510
    Abstract: A pharmaceutical composition useful for a prevention and/or treatment of hyperlipidemia, which comprises combining an effective amount of squalene synthase inhibitor and HMG-CoA reductase inhibitor is provided.
    Type: Application
    Filed: May 31, 2006
    Publication date: August 20, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tomoyuki Nishimoto, Ryuichi Tozawa, Takeo Wada, Eiichiro Ishikawa, Toshiya Nishi, Hiroko Yamakawa