Patents by Inventor Toshiyuki Shibata

Toshiyuki Shibata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240097980
    Abstract: A common control unit (141A) acquires a configuration input request to a communication device accommodating a user using a network. An individual control unit (142A) identifies a variable group necessary for a command to execute the configuration input based on request content of the configuration input received by the common control unit (141A) and a type of communication device and transmits the identified variable group to the common control unit (141A). A command execution unit (143A) acquires the variable group identified by the individual control unit (141A) from the common control unit (141A), generates a command based on the acquired variable group, and executes the generated command.
    Type: Application
    Filed: February 16, 2021
    Publication date: March 21, 2024
    Inventors: Hiroki IWAHASHI, Takahiro SHIBATA, Toshiyuki KANAZAWA, Masato NISHIGUCHI
  • Publication number: 20230404938
    Abstract: A method of treating a patient in need thereof includes administering a therapeutically effective amount of 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) to serve or function as a nerve growth factor (NGF) activity promoter, preferably to treat and/or prevent a neurodegenerative disease, such as PolyQ disease, Parkinson's disease, Parkinson's syndrome, spinocerebellar degeneration, spastic paraplegia, amyotrophic lateral sclerosis, Alzheimer's disease, dementia with Lewy bodies or corticobasal degeneration.
    Type: Application
    Filed: March 16, 2023
    Publication date: December 21, 2023
    Applicant: MIE UNIVERSITY
    Inventors: Toshiyuki SHIBATA, Hideo MIYAKE, Reiji TANAKA, Fumino OKUDA, Mano HASEGAWA
  • Patent number: 10927363
    Abstract: Alginate lyase activity is exhibited by the amino acid sequences (polypeptides) shown in SEQ ID No:1 and SEQ ID No:2. These polypeptides and their homology equivalents are used to produce 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) by contacting the polypeptide(s) with an alginate containing a uronic acid moiety and holding the mixture of the alginate and the polypeptide(s) at a temperature at which alginate lyase activity is exhibited.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: February 23, 2021
    Assignee: MIE UNIVERSITY
    Inventors: Toshiyuki Shibata, Hideo Miyake, Yoshihiro Murase, Reiji Tanaka, Tetsushi Mori, Haruko Takeyama, Mami Takahashi
  • Publication number: 20190127722
    Abstract: Alginate lyase activity is exhibited by the amino acid sequences (polypeptides) shown in SEQ ID No:1 and SEQ ID No:2. These polypeptides and their homology equivalents are used to produce 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) by contacting the polypeptide(s) with an alginate containing a uronic acid moiety and holding the mixture of the alginate and the polypeptide(s) at a temperature at which alginate lyase activity is exhibited.
    Type: Application
    Filed: April 3, 2017
    Publication date: May 2, 2019
    Inventors: Toshiyuki SHIBATA, Hideo MIYAKE, Yoshihiro MURASE, Reiji TANAKA, Tetsushi MORI, Haruko TAKEYAMA, Mami TAKAHASHI
  • Patent number: 9890360
    Abstract: A method that includes bringing a nuclear reprogramming substance (DLX4 gene, OCT3/4 gene, and SOX2 gene) into contact with a cell and thereby producing iPS cells.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: February 13, 2018
    Assignees: GIFU UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Kenichi Tezuka, Naritaka Tamaoki, Kazuki Iida, Tomoko Kawaguchi, Hitomi Aoki, Takahiro Kunisada, Toshiyuki Shibata, Naoki Goshima
  • Patent number: 9776160
    Abstract: A catalyst recovery system that includes a concentrated slurry production unit that concentrates a slurry extracted from a reactor main unit and continuously produces a concentrated slurry, a first discharge unit that discharges the concentrated slurry from the concentrated slurry production unit, a solidified slurry production unit that cools the concentrated slurry discharged from the concentrated slurry production unit, thereby solidifying the liquid medium within the concentrated slurry and producing a solidified slurry, and a recovery mechanism that recovers the solidified slurry from the solidified slurry production unit.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: October 3, 2017
    Assignees: Japan Oil, Gas and Metals National Corporation, INPEX CORPORATION, JX Nippon Oil & Energy Corporation, Japan Petroleum Exploration Co., Ltd., COSMO OIL CO., LTD., NIPPON STEEL & SUMIKIN ENGINEERING CO., LTD.
    Inventors: Toshiyuki Shibata, Hidekatsu Honda, Akira Kawamura
  • Publication number: 20160296669
    Abstract: An object of the present invention is to provide a method for efficiently and reproducibly producing a graft material having a high recovery effect on dysfunction caused by nerve damage. The present invention provides a method for producing a graft material for treating nerve damage, including a step of culturing a dental pulp stem cell in a medium substantially containing no growth factors except FGF2, and others.
    Type: Application
    Filed: May 14, 2014
    Publication date: October 13, 2016
    Inventors: Kenichi TEZUKA, Tomoko KAWAGUCHI, Takahiro KUNISADA, Toshiyuki SHIBATA, Hidefumi FUKUMITSU, Shoei FURUKAWA
  • Publication number: 20160208218
    Abstract: A method that includes bringing a nuclear reprogramming substance (DLX4 gene, OCT3/4 gene, and SOX2 gene) into contact with a cell and thereby producing iPS cells.
    Type: Application
    Filed: August 28, 2014
    Publication date: July 21, 2016
    Applicants: GIFU UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Kenichi TEZUKA, Naritaka TAMAOKI, Kazuki IIDA, Tomoko KAWAGUCHI, Hitomi AOKI, Takahiro KUNISADA, Toshiyuki SHIBATA, Naoki GOSHIMA
  • Publication number: 20140004011
    Abstract: A catalyst recovery system that includes a concentrated slurry production unit that concentrates a slurry extracted from a reactor main unit and continuously produces a concentrated slurry, a first discharge unit that discharges the concentrated slurry from the concentrated slurry production unit, a solidified slurry production unit that cools the concentrated slurry discharged from the concentrated slurry production unit, thereby solidifying the liquid medium within the concentrated slurry and producing a solidified slurry, and a recovery mechanism that recovers the solidified slurry from the solidified slurry production unit.
    Type: Application
    Filed: January 13, 2012
    Publication date: January 2, 2014
    Applicants: JAPAN OIL, GAS AND METALS NATIONAL CORPORATION, INPEX CORPORATION, NIPPON STEEL & SUMIKIN ENGINEERING CO., LTD., JAPAN PETROLEUM EXPLORATION CO., LTD., COSMO OIL CO., LTD., JX NIPPON OIL & ENERGY CORPORATION
    Inventors: Toshiyuki Shibata, Hidekatsu Honda, Akira Kawamura
  • Publication number: 20110201110
    Abstract: The present invention provides a method of producing induced pluripotent stem (iPS) cells, comprising bringing a nuclear reprogramming substance into contact with dental pulp stem cells. By using dental pulp stem cells as a source of somatic cells, the efficiency of establishment of human iPS cells by transfer of 3 or 4 factors can be improved dramatically. Additionally, dental pulp stem cells are easily available because they can be isolated and prepared from extracted wisdom teeth and teeth extracted because of periodontal disease and the like, so that they can be used widely as a source of somatic cells for iPS cell banks.
    Type: Application
    Filed: October 2, 2008
    Publication date: August 18, 2011
    Applicants: GIFU UNIVERSITY, KYOTO UNIVERSITY
    Inventors: Kenichi Tezuka, Toshiyuki Shibata, Takahiro Kunisada, Naritaka Tamaoki, Tomoko Takeda, Shinya Yamanaka, Kazutoshi Takahashi
  • Patent number: 6158079
    Abstract: A wiper arm for driving a wiper blade to wipe a windshield of a vehicle. The wiper arm is composed of an arm head, a retainer, an arm piece and a coil spring for urging the wiper blade against the windshield. The retainer has an inclining front surface to prevent dynamic lift by air flow, and a coil spring is disposed to align with a common longitudinal center line of the retainer and the arm head to prevent an angular moment.
    Type: Grant
    Filed: December 7, 1998
    Date of Patent: December 12, 2000
    Assignee: ASMO Co., Ltd.
    Inventor: Toshiyuki Shibata
  • Patent number: 6119301
    Abstract: An object of this invention is to provide a wiper device of a vehicle capable of preventing foreign matter from being caught in a link mechanism of a four-articulation link system type wiper arm, capable of maintaining its function under severe conditions and of being realized through a simple structure at low cost. This wiper device of the vehicle is of the four-articulation link system in which a main lever and a sub lever are each connected to an arm head. A cover member is mounted on the arm head with engaging pieces and engaging concave portions. The cover member covers a link mechanism portion. A mesh-like rib is formed at a back side of the cover member so as to improve rigidity. As a result, it is possible to block penetration of snow or the like and remove (wipe off) accumulated snow and formed ice by force, thereby preventing an increase in the accumulated snow.
    Type: Grant
    Filed: December 8, 1998
    Date of Patent: September 19, 2000
    Assignee: ASMO Co., Ltd.
    Inventors: Tetsuya Nakatsukasa, Toshiyuki Shibata, Nobuaki Kinoshita
  • Patent number: 5665711
    Abstract: An antitumor composition for oral administration, comprising a 2'-deoxy-2'-methylidenecytidine compound of the formula ##STR1## wherein R is a hydrogen or a halogen, and R.sup.1 and R.sup.2 are the same or different and each is a hydrogen, a halogen or an alkyl having 1 to 4 carbon atoms, an acid addition salt thereof or a hydrate thereof, and a sucrose ester of fatty acid(s). The pharmaceutical composition of the present invention comprising a DMDC compound useful as an antitumor agent based on its remarkable degenerative action on solid tumor shows an improved oral absorption.
    Type: Grant
    Filed: December 12, 1995
    Date of Patent: September 9, 1997
    Assignee: Yoshitomi Pharmaceutical Industries, Ltd.
    Inventors: Atsushi Sakai, Kyouichi Hirotsu, Hirotsugu Tada, Toshiyuki Shibata
  • Patent number: 5589491
    Abstract: An injection solution comprising a 2-[(2-pyridyl)methylsulfinyl]-benzimidazole compound or a salt thereof having antiulcer activity and an aqueous solvent added with no nonaqueous solvent is disclosed wherein the pH is not less than 9.5 and not more than 11.5.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: December 31, 1996
    Assignee: Astra Aktiebolag
    Inventors: Shigeo Nakanishi, Tetsuo Tominaga, Iwao Yamanaka, Takashi Higo, Toshiyuki Shibata
  • Patent number: 5183882
    Abstract: Novel stable, non-hygroscopic 2'-deoxy-2'-methylidenecytidine dihydrate and its methods for production, and compositions with improved solubility containing same and saccharide(s).
    Type: Grant
    Filed: February 19, 1991
    Date of Patent: February 2, 1993
    Assignees: Yoshitomi Pharmaceutical Industries, Ltd., Yamasa Shoyu Co., Ltd.
    Inventors: Shinji Sakata, Takanori Miyashita, Kazuhiko Kondo, Atsushi Sakai, Toshiyuki Shibata, Takayuki Ogawa
  • Patent number: 4180546
    Abstract: A process for removing a phosphorus component from fluorite containing such phosphorus component, which process comprises adding powder of the fluorite to an aqueous acid solution having an acid concentration of from 1.0 to 20 Wt% in an inorganic acid/phosphorus ratio of above 25:1 by mole to give a slurry, agitating the slurry at a temperature below 50.degree. C., and collecting the powder from the slurry. The mother liquor obtained after separation of the powder from the slurry may be recycled to the first step.
    Type: Grant
    Filed: July 19, 1978
    Date of Patent: December 25, 1979
    Assignee: Central Glass Company, Limited
    Inventors: Toshiyuki Shibata, Hiroshi Ono, Kenji Isoyama