Patents by Inventor Toshiyuki Shibata
Toshiyuki Shibata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240097980Abstract: A common control unit (141A) acquires a configuration input request to a communication device accommodating a user using a network. An individual control unit (142A) identifies a variable group necessary for a command to execute the configuration input based on request content of the configuration input received by the common control unit (141A) and a type of communication device and transmits the identified variable group to the common control unit (141A). A command execution unit (143A) acquires the variable group identified by the individual control unit (141A) from the common control unit (141A), generates a command based on the acquired variable group, and executes the generated command.Type: ApplicationFiled: February 16, 2021Publication date: March 21, 2024Inventors: Hiroki IWAHASHI, Takahiro SHIBATA, Toshiyuki KANAZAWA, Masato NISHIGUCHI
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Publication number: 20230404938Abstract: A method of treating a patient in need thereof includes administering a therapeutically effective amount of 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) to serve or function as a nerve growth factor (NGF) activity promoter, preferably to treat and/or prevent a neurodegenerative disease, such as PolyQ disease, Parkinson's disease, Parkinson's syndrome, spinocerebellar degeneration, spastic paraplegia, amyotrophic lateral sclerosis, Alzheimer's disease, dementia with Lewy bodies or corticobasal degeneration.Type: ApplicationFiled: March 16, 2023Publication date: December 21, 2023Applicant: MIE UNIVERSITYInventors: Toshiyuki SHIBATA, Hideo MIYAKE, Reiji TANAKA, Fumino OKUDA, Mano HASEGAWA
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Patent number: 10927363Abstract: Alginate lyase activity is exhibited by the amino acid sequences (polypeptides) shown in SEQ ID No:1 and SEQ ID No:2. These polypeptides and their homology equivalents are used to produce 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) by contacting the polypeptide(s) with an alginate containing a uronic acid moiety and holding the mixture of the alginate and the polypeptide(s) at a temperature at which alginate lyase activity is exhibited.Type: GrantFiled: April 3, 2017Date of Patent: February 23, 2021Assignee: MIE UNIVERSITYInventors: Toshiyuki Shibata, Hideo Miyake, Yoshihiro Murase, Reiji Tanaka, Tetsushi Mori, Haruko Takeyama, Mami Takahashi
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Publication number: 20190127722Abstract: Alginate lyase activity is exhibited by the amino acid sequences (polypeptides) shown in SEQ ID No:1 and SEQ ID No:2. These polypeptides and their homology equivalents are used to produce 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) by contacting the polypeptide(s) with an alginate containing a uronic acid moiety and holding the mixture of the alginate and the polypeptide(s) at a temperature at which alginate lyase activity is exhibited.Type: ApplicationFiled: April 3, 2017Publication date: May 2, 2019Inventors: Toshiyuki SHIBATA, Hideo MIYAKE, Yoshihiro MURASE, Reiji TANAKA, Tetsushi MORI, Haruko TAKEYAMA, Mami TAKAHASHI
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Patent number: 9890360Abstract: A method that includes bringing a nuclear reprogramming substance (DLX4 gene, OCT3/4 gene, and SOX2 gene) into contact with a cell and thereby producing iPS cells.Type: GrantFiled: August 28, 2014Date of Patent: February 13, 2018Assignees: GIFU UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Kenichi Tezuka, Naritaka Tamaoki, Kazuki Iida, Tomoko Kawaguchi, Hitomi Aoki, Takahiro Kunisada, Toshiyuki Shibata, Naoki Goshima
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Patent number: 9776160Abstract: A catalyst recovery system that includes a concentrated slurry production unit that concentrates a slurry extracted from a reactor main unit and continuously produces a concentrated slurry, a first discharge unit that discharges the concentrated slurry from the concentrated slurry production unit, a solidified slurry production unit that cools the concentrated slurry discharged from the concentrated slurry production unit, thereby solidifying the liquid medium within the concentrated slurry and producing a solidified slurry, and a recovery mechanism that recovers the solidified slurry from the solidified slurry production unit.Type: GrantFiled: January 13, 2012Date of Patent: October 3, 2017Assignees: Japan Oil, Gas and Metals National Corporation, INPEX CORPORATION, JX Nippon Oil & Energy Corporation, Japan Petroleum Exploration Co., Ltd., COSMO OIL CO., LTD., NIPPON STEEL & SUMIKIN ENGINEERING CO., LTD.Inventors: Toshiyuki Shibata, Hidekatsu Honda, Akira Kawamura
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Publication number: 20160296669Abstract: An object of the present invention is to provide a method for efficiently and reproducibly producing a graft material having a high recovery effect on dysfunction caused by nerve damage. The present invention provides a method for producing a graft material for treating nerve damage, including a step of culturing a dental pulp stem cell in a medium substantially containing no growth factors except FGF2, and others.Type: ApplicationFiled: May 14, 2014Publication date: October 13, 2016Inventors: Kenichi TEZUKA, Tomoko KAWAGUCHI, Takahiro KUNISADA, Toshiyuki SHIBATA, Hidefumi FUKUMITSU, Shoei FURUKAWA
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Publication number: 20160208218Abstract: A method that includes bringing a nuclear reprogramming substance (DLX4 gene, OCT3/4 gene, and SOX2 gene) into contact with a cell and thereby producing iPS cells.Type: ApplicationFiled: August 28, 2014Publication date: July 21, 2016Applicants: GIFU UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Kenichi TEZUKA, Naritaka TAMAOKI, Kazuki IIDA, Tomoko KAWAGUCHI, Hitomi AOKI, Takahiro KUNISADA, Toshiyuki SHIBATA, Naoki GOSHIMA
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Publication number: 20140004011Abstract: A catalyst recovery system that includes a concentrated slurry production unit that concentrates a slurry extracted from a reactor main unit and continuously produces a concentrated slurry, a first discharge unit that discharges the concentrated slurry from the concentrated slurry production unit, a solidified slurry production unit that cools the concentrated slurry discharged from the concentrated slurry production unit, thereby solidifying the liquid medium within the concentrated slurry and producing a solidified slurry, and a recovery mechanism that recovers the solidified slurry from the solidified slurry production unit.Type: ApplicationFiled: January 13, 2012Publication date: January 2, 2014Applicants: JAPAN OIL, GAS AND METALS NATIONAL CORPORATION, INPEX CORPORATION, NIPPON STEEL & SUMIKIN ENGINEERING CO., LTD., JAPAN PETROLEUM EXPLORATION CO., LTD., COSMO OIL CO., LTD., JX NIPPON OIL & ENERGY CORPORATIONInventors: Toshiyuki Shibata, Hidekatsu Honda, Akira Kawamura
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Publication number: 20110201110Abstract: The present invention provides a method of producing induced pluripotent stem (iPS) cells, comprising bringing a nuclear reprogramming substance into contact with dental pulp stem cells. By using dental pulp stem cells as a source of somatic cells, the efficiency of establishment of human iPS cells by transfer of 3 or 4 factors can be improved dramatically. Additionally, dental pulp stem cells are easily available because they can be isolated and prepared from extracted wisdom teeth and teeth extracted because of periodontal disease and the like, so that they can be used widely as a source of somatic cells for iPS cell banks.Type: ApplicationFiled: October 2, 2008Publication date: August 18, 2011Applicants: GIFU UNIVERSITY, KYOTO UNIVERSITYInventors: Kenichi Tezuka, Toshiyuki Shibata, Takahiro Kunisada, Naritaka Tamaoki, Tomoko Takeda, Shinya Yamanaka, Kazutoshi Takahashi
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Patent number: 6158079Abstract: A wiper arm for driving a wiper blade to wipe a windshield of a vehicle. The wiper arm is composed of an arm head, a retainer, an arm piece and a coil spring for urging the wiper blade against the windshield. The retainer has an inclining front surface to prevent dynamic lift by air flow, and a coil spring is disposed to align with a common longitudinal center line of the retainer and the arm head to prevent an angular moment.Type: GrantFiled: December 7, 1998Date of Patent: December 12, 2000Assignee: ASMO Co., Ltd.Inventor: Toshiyuki Shibata
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Patent number: 6119301Abstract: An object of this invention is to provide a wiper device of a vehicle capable of preventing foreign matter from being caught in a link mechanism of a four-articulation link system type wiper arm, capable of maintaining its function under severe conditions and of being realized through a simple structure at low cost. This wiper device of the vehicle is of the four-articulation link system in which a main lever and a sub lever are each connected to an arm head. A cover member is mounted on the arm head with engaging pieces and engaging concave portions. The cover member covers a link mechanism portion. A mesh-like rib is formed at a back side of the cover member so as to improve rigidity. As a result, it is possible to block penetration of snow or the like and remove (wipe off) accumulated snow and formed ice by force, thereby preventing an increase in the accumulated snow.Type: GrantFiled: December 8, 1998Date of Patent: September 19, 2000Assignee: ASMO Co., Ltd.Inventors: Tetsuya Nakatsukasa, Toshiyuki Shibata, Nobuaki Kinoshita
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Patent number: 5665711Abstract: An antitumor composition for oral administration, comprising a 2'-deoxy-2'-methylidenecytidine compound of the formula ##STR1## wherein R is a hydrogen or a halogen, and R.sup.1 and R.sup.2 are the same or different and each is a hydrogen, a halogen or an alkyl having 1 to 4 carbon atoms, an acid addition salt thereof or a hydrate thereof, and a sucrose ester of fatty acid(s). The pharmaceutical composition of the present invention comprising a DMDC compound useful as an antitumor agent based on its remarkable degenerative action on solid tumor shows an improved oral absorption.Type: GrantFiled: December 12, 1995Date of Patent: September 9, 1997Assignee: Yoshitomi Pharmaceutical Industries, Ltd.Inventors: Atsushi Sakai, Kyouichi Hirotsu, Hirotsugu Tada, Toshiyuki Shibata
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Patent number: 5589491Abstract: An injection solution comprising a 2-[(2-pyridyl)methylsulfinyl]-benzimidazole compound or a salt thereof having antiulcer activity and an aqueous solvent added with no nonaqueous solvent is disclosed wherein the pH is not less than 9.5 and not more than 11.5.Type: GrantFiled: January 18, 1995Date of Patent: December 31, 1996Assignee: Astra AktiebolagInventors: Shigeo Nakanishi, Tetsuo Tominaga, Iwao Yamanaka, Takashi Higo, Toshiyuki Shibata
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Patent number: 5183882Abstract: Novel stable, non-hygroscopic 2'-deoxy-2'-methylidenecytidine dihydrate and its methods for production, and compositions with improved solubility containing same and saccharide(s).Type: GrantFiled: February 19, 1991Date of Patent: February 2, 1993Assignees: Yoshitomi Pharmaceutical Industries, Ltd., Yamasa Shoyu Co., Ltd.Inventors: Shinji Sakata, Takanori Miyashita, Kazuhiko Kondo, Atsushi Sakai, Toshiyuki Shibata, Takayuki Ogawa
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Patent number: 4180546Abstract: A process for removing a phosphorus component from fluorite containing such phosphorus component, which process comprises adding powder of the fluorite to an aqueous acid solution having an acid concentration of from 1.0 to 20 Wt% in an inorganic acid/phosphorus ratio of above 25:1 by mole to give a slurry, agitating the slurry at a temperature below 50.degree. C., and collecting the powder from the slurry. The mother liquor obtained after separation of the powder from the slurry may be recycled to the first step.Type: GrantFiled: July 19, 1978Date of Patent: December 25, 1979Assignee: Central Glass Company, LimitedInventors: Toshiyuki Shibata, Hiroshi Ono, Kenji Isoyama