Abstract: Peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing at least one of an integrin binding motif such as an RGD sequence, a glycosaminoglycan binding motif, and a calcium binding motif, and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for injection or dispersed in toothpaste or a mouthwash or gum patch and administered to enhance bone/tooth growth and/or reduce excessive urinary phosphate loss from the body.

Abstract: Peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing at least one of an integrin binding motif such as an RGD sequence, a glycosaminoglycan binding motif, and a calcium binding motif, and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for injection or dispersed in toothpaste or a mouthwash or gum patch and administered to enhance bone/tooth growth and/or reduce excessive urinary phosphate loss from the body.

Abstract: The present invention aims to provide a plane light source device having enhanced efficiency of use of light and high brightness uniformity. A plane light source device of the present invention is provided with a housing having an opening section, a scattering plate arranged at the opening section for scattering incoming light and a light source arranged at one side face in the housing, wherein a regular reflection section for regularly reflecting light incoming from the light source is provided in the vicinity of the light source at the bottom surface of the housing that is opposite to the scattering plate and a scatter reflection section for irregularly reflecting light incoming from the light source is provided so as to be adjacent to the regular reflection section.

Abstract: Dental products such as toothpastes, mouthwash and dental floss are disclosed which products are enhanced by having dissolved, dispersed or coated thereon a compound which promoted bone growth. Preferred compounds are peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing an integrin binding motif such as RGD sequence and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for dispersed in toothpaste or a mouthwash and administered to enhance bone/tooth growth. When the dental products are used repeatedly over time they enhance good dental health.

Abstract: The liquid crystal display device has red, green, and blue LEDs, each emitting a different color light, as a light source. An acrylic lens is mounted on the emission surface of the LED to change angular distributions of light from the LED. The shape of the acrylic lens varies depending on the color of the LED. The angular distribution of emitting light thereby differs by the color of LED to cancel out wavelength dependency of transmittance at each viewing direction in a liquid crystal panel.

Abstract: To provide a planar light source device capable of preventing abnormal light emittance at a vicinity of a lamp without causing deterioration in brightness and disadvantage in view of structure and a liquid crystal display having high display grade, by projecting a reflection sheet 4 from a light guiding plate 3 to inside of a lamp reflector 2 and providing notch portions 5 at both end portions of the reflection sheet 4 projected to inside of the lamp reflector 2, interference between the projected reflection sheet 4 and electrode portions or lamp holders 1a at both ends of the lamp 1 is prevented from causing.

Abstract: A thin flat-surface type display device having a transmissive display panel is provided, which is capable of securing a space of an essential electric circuit for driving the display device without deteriorating an optical performance (luminance and uniformity thereof) of a surface light source device of an edge light system employed as a backlight. A light guide plate forming the surface light source device of the edge light system has a flat light emitting surface, and a back surface arranged so as to include (1) an inclined flat surface portion where a thickness of the light guide plate decreases linearly from a light-incident portion on which light emitted from a linear light source is incident toward a light-anti-incident portion, and (2) a parallel flat surface portion which is parallel with the light emitting surface in the vicinity of the light-anti-incident portion.

Abstract: Peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing at least one of an integrin binding motif such as an RGD sequence, a glycosaminoglycan binding motif, and a calcium binding motif, and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for injection or dispersed in toothpaste or a mouthwash or gum patch and administered to enhance bone/tooth growth and/or reduce excessive urinary phosphate loss from the body.

Abstract: Antagonists of &agr;4 integrin/&agr;4 integrin ligand adhesion, which inhibit the biological effects of such adhesion are described and methods for their use are detailed. Such antagonists are useful in suppressing bone destruction associated with multiple myeloma. The homing of multiple myeloma cells to bone marrow and their &agr;4 integrin-dependent release of bone-resorbing factors, resulting in bone destruction in patients with multiple myeloma, is inhibited.

Abstract: Antagonists of &agr;4 integrin/&agr;4 integrin ligand adhesion, which inhibit the biological effects of such adhesion are described and methods for their use are detailed. Such antagonists are useful in suppressing bone destruction associated with multiple myeloma. The homing of multiple myeloma cells to bone marrow and their &agr;4 integrin-dependent release of bone-resorbing factors, resulting in bone destruction in patients with multiple myeloma, is inhibited.

Abstract: Antagonists of alpha 4 integri/alpha 4 integrin ligand adhesion, which inhibit the biological effects of such adhesion are described and methods for their use are detailed. Such antagonists are eseful in supressing bone destruction associated with multiple myeloma.

Abstract: To provide a planar light source device capable of preventing abnormal light emittance at a vicinity of a lamp without causing deterioration in brightness and disadvantage in view of structure and a liquid crystal display having high display grade, by projecting a reflection sheet 4 from a light guiding plate 3 to inside of a lamp reflector 2 and providing notch portions 5 at both end portions of the reflection sheet 4 projected to inside of the lamp reflector 2, interference between the projected reflection sheet 4 and electrode portions or lamp holders 1a at both ends of the lamp 1 is prevented from causing.

Abstract: Materials immunoreactive with parathyroid hormone-related protein (PTH-rp) are used in the invention method to prevent and treat cancer metastasis to bone and cancer cell growth in bone as well as osteolysis and symptomatic sequelae thereof. Antibodies with human characteristics are included in the invention for application of the invention method to human subjects.

Abstract: A dichroic mirror for reflecting red light for optical separating and a dichroic mirror for reflecting red light for optical synthesizing are installed on the same plane in an image generating apparatus of the present invention. In addition, a dichroic mirror for reflecting blue light for optical separating and a dichroic mirror for reflecting blue light for optical synthesizing are installed on the same plane. Accordingly, a compact configuration can be realized. Since a main reflecting mirror is a rotating elliptic mirror and a lamp is located on a focus or around the focus, a lighting equipment which irradiates conic luminous flux can be realized.

Abstract: Materials immunoreactive with parathyroid hormone-related protein (PTH-rp) are used in the invention method to prevent and treat metastasis and cancer cell growth in bone as well as osteolysis and symptomatic sequelae thereof. Humanized antibodies are included in the invention for application of the invention method to human subjects.