Patents by Inventor Toshizo Shiga

Toshizo Shiga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • New thiazolidine derivatives, process for preparing same and anti-amnestic composition containing same
    Patent number: 5411976
    Abstract: New thiazolidine derivatives of the general formula: ##STR1## wherein X stands for a proline or thioproline residue and R for --CH.sub.2 OH or --CHO, a process for preparing the same which comprises reacting N-benzyloxycarbonyl-L-proline or --L-thioproline with L-thioprolinol and, if necessary, oxidizing the resultant N-benzyloxycarbonyl-L-prolyl-L-thioprolinol or --L-thioprolyl-L-thioprolinol to the corresponding thioprolinal compound, and an anti-amnestic composition containing at least one of the thiazolidine derivatives together with a conventional excipient. The new thiazolidine derivatives are extremely strong in anti-amnestic activity when compared with known similar anti-amnestic agents.
    Type: Grant
    Filed: December 19, 1991
    Date of Patent: May 2, 1995
    Assignee: Kabushiki Kaisha Yakult Nonsha
    Inventors: Kunio Kado, Toshizo Shiga