Patents by Inventor Tova Chajek

Tova Chajek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic animals expressing heparanase and uses thereof
    Publication number: 20030217375
    Abstract: A transgenic non-human animal expressing heparanase from a transgene, methods for its preparation, compositions-of-matter derived therefrom and uses thereof.
    Type: Application
    Filed: February 24, 2003
    Publication date: November 20, 2003
    Inventors: Eyal Zcharia, Israel Vlodavsky, Shula Metzger, Iris Pecker, Neta Ilan, Tova Chajek-Shaul, Orit Goldshmidt
  • Transgenic animals expressing heparanase and its uses
    Publication number: 20020194625
    Abstract: A transgenic animal expressing heparanase from a transgene, methods for its preparation, compositions-of-matter derived therefrom and its uses.
    Type: Application
    Filed: May 25, 2001
    Publication date: December 19, 2002
    Applicant: Insight Strategy & Marketing Ltd.
    Inventors: Eyal Zcharia, Israel Vlodavsky, Shula Metzger, Tova Chajek-Shaul, Orit Goldshmidt, Iris Pecker, Neta Ilan
  • Therapeutic lipoprotein compositions
    Patent number: 5948756
    Abstract: A lipoprotein particle and a therapeutic lipoprotein composition are disclosed. The lipoprotein particle consists essentially of lecithin phospholipids with low phase transition temperatures and human apoproteins A and C. A therapeutic composition for therapeutic administration to a subject, comprising the lipoprotein particles of the invention, is also disclosed. The composition is useful is treating disease conditions associated with elevated serum Lp(a) levels, as well as hypertension and acute renal failure.
    Type: Grant
    Filed: August 31, 1995
    Date of Patent: September 7, 1999
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Yechezkel Barenholz, Hilary Shmeeda, Tova Chajek
  • Method for reducing serum lipoprotein (A) concentration
    Patent number: 5914311
    Abstract: A method of reducing serum Lp(a) concentration in a subject is accomplished by administration of liposomes. A suspension of small, unilamellar vesicles composed primarily of phosphatidylcholine phospholipids is administered parenterally to a subject having or at risk for developing a disease condition associated with an elevated serum Lp(a) concentration. The liposomes are infused over a period of time such that a significant drop in serum Lp(a) concentration is observed.
    Type: Grant
    Filed: May 19, 1998
    Date of Patent: June 22, 1999
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Yechezkel Barenholz, Hilary Shmeeda, Tova Chajek
  • Method for reducing serum lipoprotein(a) concentration
    Patent number: 5741514
    Abstract: A method of reducing the serum Lp(a) concentration in a subject is disclosed. A suspension of small, unilamellar vesicles composed primarily of phospholipids, similar in nature to those of egg phosphatidylcholine, is administered parenterally to a subject having or at risk for developing a disease condition associated with an elevated serum Lp(a) concentration. In the method, liposomes are infused over an extended period of time of at least several weeks, until a significant drop in serum Lp(a) concentration is observed.
    Type: Grant
    Filed: August 31, 1995
    Date of Patent: April 21, 1998
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Yechezkel Barenholz, Hilary Shmeeda, Tova Chajek