Patents by Inventor Toyokazu Kurushima

Toyokazu Kurushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070172812
    Abstract: A tissue equivalent for transplantation having a three-dimensional structure which is cultured in vitro, contains cells to be transplanted and which can be transplanted into a living body after the culture, characterized by including a scaffold layer mainly culturing a scaffold constituting the three-dimensional structure and a cell layer which is localized at least in a part of the surface of the tissue equivalent for transplantation continuously with the scaffold layer and which contains the cells to be transplanted or extra cellular matrix in a larger amount than the scaffold layer. This tissue equivalent is appropriately employed as a tissue equivalent for transplantation in a relatively large size. This tissue equivalent enables realization of prompt fixation to the neighborhood of the transplanted tissue and prevention of falling off.
    Type: Application
    Filed: March 27, 2007
    Publication date: July 26, 2007
    Inventors: Mitsuo Ochi, Yuji Uchio, Kenzo Kawasaki, Masakazu Katoh, Takeyuki Yamamoto, Rika Fukushima, Toyokazu Kurushima
  • Patent number: 7198908
    Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: April 3, 2007
    Assignees: Japan Tissue Engineering Co., Ltd.
    Inventors: Mitsuo Ochi, Junji Iwasa, Masatoshi Tobita, Masakazu Katoh, Takeyuki Yamamoto, Rika Fukushima, Toyokazu Kurushima
  • Publication number: 20050019748
    Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.
    Type: Application
    Filed: August 19, 2004
    Publication date: January 27, 2005
    Inventors: Mitsuo Ochi, Junji Iwasa, Masatoshi Tobita, Masakazu Katoh, Takeyuki Yamamoto, Rika Fukushima, Toyokazu Kurushima
  • Patent number: 6815179
    Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: November 9, 2004
    Assignees: Japan Tissue Engineering Co., Ltd.
    Inventors: Mitsuo Ochi, Junji Iwasa, Masatoshi Tobita, Masakazu Katoh, Takeyuki Yamamoto, Rika Fukushima, Toyokazu Kurushima
  • Publication number: 20040030406
    Abstract: A tissue equivalent for transplantation having a three-dimensional structure which is cultured in vitro, contains cells to be transplanted and which can be transplanted into a living body after the culture, characterized by including a scaffold layer mainly culturing a scaffold constituting the three-dimensional structure and a cell layer which is localized at least in a part of the surface of the tissue equivalent for transplantation continuously with the scaffold layer and which contains the cells to be transplanted or extra cellular matrix in a larger amount than the scaffold layer. This tissue equivalent is appropriately employed as a tissue equivalent for transplantation in a relatively large size. This tissue equivalent enables realization of prompt fixation to the neighborhood of the transplanted tissue and prevention of falling off.
    Type: Application
    Filed: June 5, 2003
    Publication date: February 12, 2004
    Inventors: Mitsuo Ochi, Yuji Uchio, Kenzo Kawasaki, Masakazu Katoh, Takeyuki Yamamoto, Rika Fukushima, Toyokazu Kurushima
  • Publication number: 20020115197
    Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.
    Type: Application
    Filed: August 23, 2001
    Publication date: August 22, 2002
    Applicant: MITSUO OCHI and JAPAN TISSUE ENGINEERING CO.,LTD.
    Inventors: Mitsuo Ochi, Junji Iwasa, Masatoshi Tobita, Masakazu Katoh, Takeyuki Yamamoto, Rika Fukushima, Toyokazu Kurushima
  • Publication number: 20020115060
    Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.
    Type: Application
    Filed: February 27, 2002
    Publication date: August 22, 2002
    Applicant: MITSUO OCHI and JAPAN TISSUE ENGINEERING CO., LTD.
    Inventors: Mitsuo Ochi, Junji Iwasa, Masatoshi Tobita, Masakazu Katoh, Takeyuki Yamamoto, Rika Fukushima, Toyokazu Kurushima
  • Patent number: 4943298
    Abstract: A cerebral aneurysm clip composed of blade parts capable of clipping the root of a lump of cerebral aneurysm and a spring part of imparting a clipping force to the said blade parts, which is characterized in that the said blade parts are made of a synthetic resin or ceramic.
    Type: Grant
    Filed: June 2, 1989
    Date of Patent: July 24, 1990
    Assignees: Inax Corporation, Shigekiyo Fujita
    Inventors: Shigekiyo Fujita, Toyokazu Kurushima, Hiroaki Kuno, Hiromitsu Hiraiwa
  • Patent number: 4853276
    Abstract: There is provided a novel marble-translucent thin resilient decorative sheet 1, which comprises thin permeable pulp paper 2, fine whitish inorganic filler powder, and a substantially transparent cured resin contained by impregnation throughout the pulp paper, said filler powder being uniformly deposited onto at least the top surface of the pulp paper and being firmly fixed thereto. The decorative sheet is produced by impregnating fine whitish inorganic filler-loaded permeable pulp paper with a liquid polymerizable resinous composition for forming a substantially transparent cured resin, placing the impregnated pulp paper between molding plates, and polymerizing the resinous composition into a cured resin; or by impregnating permeable non-loaded pulp paper containing no filler powder with the liquid resinous composition containing fine whitish inorganic filler powder and carrying out the polymerization between molding plates as described above.
    Type: Grant
    Filed: July 16, 1987
    Date of Patent: August 1, 1989
    Assignee: Inax Corporation
    Inventor: Toyokazu Kurushima