Abstract: The present disclosure describes a replacement valve that can remove or lacerate the anterior mitral leaflet (or other portion of the heart) to reduce the obstruction of the left ventricular outflow tract (LVOT). The replacement valve can include integrated cutting features to lacerate a leaflet of a heart valve. For example, the cutting features can include blades or electrosurgical features that can cut the leaflets to reduce obstruction of the LVOT. As the cutting features are integrated components of the replacement valve, the laceration of the leaflet can follow implantation of the replacement valve and enables for clinical decisions to be made based on the degree of obstruction to the LVOT following the implantation procedure.

Abstract: Systems and methods for occluding a body cavity including providing an implantable void-filling device, wherein the implantable void-filling device includes an inflatable implant that defines an interior of the implantable void-filling device. The inflatable implant is capable of being filled with an inflation material to cause the inflatable implant to expand from a collapsed configuration to an expanded configuration. The implantable void-filling device also includes a connection hub attached to an exterior surface of the inflatable implant and a plurality of independent anchors coupled to and extending out from the connection hub along the length of the inflatable implant, such that the plurality of anchors collectively surround the inflatable implant. The connection hub and anchors are configured such that expansion of the anchors away from the surface of the inflatable implant anchors the void filling device to a body tissue.