Patents by Inventor Tracy J. Mincer

Tracy J. Mincer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salinosporamides and methods for use thereof
    Patent number: 8217072
    Abstract: The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian cells. The CNB392 and CNB476 strains lie within the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by this strain are classified as salinosporamides, and are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC50 values, high pharmaceutical potency, and selectivity for cancer cells over fungi.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: July 10, 2012
    Assignee: The Regents of the University of California
    Inventors: William H. Fenical, Paul R. Jensen, Tracy J. Mincer, Robert H. R. Feling
  • Marine actinomycete taxon for drug and fermentation product discovery
    Patent number: 7928138
    Abstract: The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: April 19, 2011
    Assignee: Regents of the University of California
    Inventors: Robert H. R. Feling, William Fenical, Paul R. Jensen, Tracy J. Mincer
  • Marine actinomycete taxon for drug and fermentation product discovery
    Patent number: 7879576
    Abstract: The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: February 1, 2011
    Assignee: Regents of the University of California
    Inventors: William Fenical, Paul R. Jensen, Tracy J. Mincer
  • SALINOSPORAMIDES AND METHODS FOR USE THEREOF
    Publication number: 20090318529
    Abstract: The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian cells. The CNB392 and CNB476 strains lie within the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by this strain are classified as salinosporamides, and are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC50 values, high pharmaceutical potency, and selectivity for cancer cells over fungi.
    Type: Application
    Filed: June 18, 2004
    Publication date: December 24, 2009
    Inventors: William H. Fenical, Paul R. Jensen, Tracy J. Mincer, Robert H.R. Feling
  • MARINE ACTINOMYCETE TAXON FOR DRUG AND FERMENTATION PRODUCT DISCOVERY
    Publication number: 20090197937
    Abstract: The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors.
    Type: Application
    Filed: December 28, 2007
    Publication date: August 6, 2009
    Inventors: William Fenical, Paul R. Jensen, Tracy J. Mincer, Robert H. R. Feling
  • MARINE ACTINOMYCETE TAXON FOR DRUG AND FERMENTATION PRODUCT DISCOVERY
    Publication number: 20090069401
    Abstract: The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors.
    Type: Application
    Filed: December 28, 2007
    Publication date: March 12, 2009
    Inventors: William Fenical, Paul R. Jensen, Tracy J. Mincer
  • Marine actinomycete taxon for drug and fermentation product discovery
    Patent number: 7144723
    Abstract: The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: December 5, 2006
    Assignee: The Regents of the University of California
    Inventors: William Fenical, Paul R. Jensen, Tracy J. Mincer
  • Marine actinomycete taxon for drug and fermentation product discovery
    Publication number: 20030157695
    Abstract: The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors.
    Type: Application
    Filed: November 16, 2001
    Publication date: August 21, 2003
    Inventors: William Fenical, Paul R. Jensen, Tracy J. Mincer