Abstract: The invention provides CARs (CARs) that specifically bind to BCMA (B-Cell Maturation Antigen). The invention further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and methods of making such CARs, engineered immune cells, and nucleic acids. The invention further relates to therapeutic methods for use of these CARs and engineered immune cells for the treatment of a condition associated with malignant cells expressing BCMA (e.g., cancer).

Abstract: The invention pertains to the conversion of waste materials derived from gypsum mining and processing, such as existing gypsum stacks, into waste containment or landfill facilities. Advantageously, waste containment facilities and business methods according to the invention enable the creation of a positive revenue stream from previously negative assets such as gypsum stacks. Methods of the invention include the creation of waste containment facilities from existing gypsum stacks, or from the on-site formation of containment facilities from waste gypsum or other waste minerals as they are transported and positioned at a waste site. Waste containment facilities created according to the invention can be used for the short-term, long-term or permanent storage of waste materials such as solid waste, community refuse materials, biomass, industrial waste, phosphate waste, and for composting or otherwise processing materials such as biomass.

Abstract: An improved portable or traveling pet bed has a generally laminar panel that is at least partially covered on one side with material adapted to be comfortable to a pet lying on the panel. At least one hinge member is formed in the panel and divides it into first and second portions on each side of the hinge member. The first and second portions of the panel can be folded toward one another into a closed position.