Patents by Inventor Travis Gould
Travis Gould has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8994807Abstract: A system (100) and method for creating three dimensional images using probe molecules is disclosed and described. A sample is mounted on a stage (160). The sample has a plurality of probe molecules. The sample is illuminated with light, causing the probe molecules to luminesce. The probe luminescence can be split into at least four paths corresponding to at least four detection planes corresponding to object planes in the sample. The at least four detection planes are detected via a camera (155). Object planes in corresponding recorded regions of interest are recorded in the camera (155). A signal from the regions of interest is combined into a three dimensional image.Type: GrantFiled: March 18, 2010Date of Patent: March 31, 2015Assignees: University of Utah Research Foundation, University of Maine System Board of Trustees, The Jackson LaboratoryInventors: Brian Thomas Bennett, Joerg Bewersdorf, Erik Jorgensen, Sam Hess, Travis Gould, Mudalige Siyath Gunewardene
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Publication number: 20130147916Abstract: A system (100) and method for creating three dimensional images using probe molecules is disclosed and described. A sample is mounted on a stage (160). The sample has a plurality of probe molecules. The sample is illuminated with light, causing the probe molecules to luminesce. The probe luminescence can be split into at least four paths corresponding to at least four detection planes corresponding to object planes in the sample. The at least four detection planes are detected via a camera (155). Object planes in corresponding recorded regions of interest are recorded in the camera (155). A signal from the regions of interest is combined into a three dimensional image.Type: ApplicationFiled: March 18, 2010Publication date: June 13, 2013Inventors: Brian Thomas Bennett, Joerg Bewersdorf, Erik Jorgensen, Sam Hess, Travis Gould, Mudalige Siyath Gunewardene
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Publication number: 20120287244Abstract: An optical microscope (101) with heightened resolution and capable of providing three dimensional images is disclosed and described. The microscope (101) can include a sample stage (160) for mounting a sample having a plurality of probe molecules. At least one non-coherent light source (127) can be provided. At least one lens (140a, 140b) can be configured to direct a beam of light from the at least one non-coherent light source (127) toward the sample causing the probe molecules to luminesce. A camera (155) can be configured to detect luminescence from the probe molecules. A light beam path modification module (132, 150) can be configured to alter a path length of the probe molecule luminescence to allow camera luminescence detection at a plurality of object planes.Type: ApplicationFiled: September 19, 2011Publication date: November 15, 2012Inventors: Brian Thomas Bennett, Joerg Bewersdorf, Erik Jorgensen, Sam Hess, Travis Gould, Mudalige Siyath Gunewardene
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Patent number: 7880149Abstract: A microscopy system is configured for creating 3D images from individually localized probe molecules. The microscopy system includes a sample stage, an activation light source, a readout light source, a beam splitting device, at least one camera, and a controller. The activation light source activates probes of at least one probe subset of photo-sensitive luminescent probes, and the readout light source causes luminescence light from the activated probes. The beam splitting device splits the luminescence light into at least two paths to create at least two detection planes that correspond to the same or different number of object planes of the sample. The camera detects simultaneously the at least two detection planes, the number of object planes being represented in the camera by the same number of recorded regions of interest. The controller is programmable to combine a signal from the regions of interest into a 3D data.Type: GrantFiled: June 29, 2010Date of Patent: February 1, 2011Assignees: The Jackson Laboratory, University of MaineInventors: Joerg Bewersdorf, Manuel F. Juette, Travis Gould, Sam T. Hess
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Publication number: 20100265318Abstract: A microscopy system is configured for creating 3D images from individually localized probe molecules. The microscopy system includes a sample stage, an activation light source, a readout light source, a beam splitting device, at least one camera, and a controller. The activation light source activates probes of at least one probe subset of photo-sensitive luminescent probes, and the readout light source causes luminescence light from the activated probes. The beam splitting device splits the luminescence light into at least two paths to create at least two detection planes that correspond to the same or different number of object planes of the sample. The camera detects simultaneously the at least two detection planes, the number of object planes being represented in the camera by the same number of recorded regions of interest. The controller is programmable to combine a signal from the regions of interest into a 3D data.Type: ApplicationFiled: June 29, 2010Publication date: October 21, 2010Applicants: The Jackson Laboratory, University of MaineInventors: Joerg Bewersdorf, Manuel F. Juette, Travis Gould, Sam T. Hess
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Patent number: 7772569Abstract: A microscopy system is configured for creating 3D images from individually localized probe molecules. The microscopy system includes a sample stage, an activation light source, a readout light source, a beam splitting device, at least one camera, and a controller. The activation light source activates probes of at least one probe subset of photo-sensitive luminescent probes, and the readout light source causes luminescence light from the activated probes. The beam splitting device splits the luminescence light into at least two paths to create at least two detection planes that correspond to the same or different number of object planes of the sample. The camera detects simultaneously the at least two detection planes, the number of object planes being represented in the camera by the same number of recorded regions of interest. The controller is programmable to combine a signal from the regions of interest into a 3D data.Type: GrantFiled: April 1, 2008Date of Patent: August 10, 2010Assignees: The Jackson Laboratory, University of MaineInventors: Joerg Bewersdorf, Manuel F. Juette, Travis Gould, Sam T. Hess
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Publication number: 20090242798Abstract: A microscopy system is configured for creating 3D images from individually localized probe molecules. The microscopy system includes a sample stage, an activation light source, a readout light source, a beam splitting device, at least one camera, and a controller. The activation light source activates probes of at least one probe subset of photo-sensitive luminescent probes, and the readout light source causes luminescence light from the activated probes. The beam splitting device splits the luminescence light into at least two paths to create at least two detection planes that correspond to the same or different number of object planes of the sample. The camera detects simultaneously the at least two detection planes, the number of object planes being represented in the camera by the same number of recorded regions of interest. The controller is programmable to combine a signal from the regions of interest into a 3D data.Type: ApplicationFiled: April 1, 2008Publication date: October 1, 2009Applicants: The Jackson Laboratory, University of MaineInventors: Joerg Bewersdorf, Manuel F. Juette, Travis Gould, Sam T. Hess