Abstract: Devices and processing systems are configured to enable physiological event prediction based on blepharometric data analysis. For example, some embodiments provide methods and associated technology that enable retrospective analysis of blepharometric data driving subsequent hardware/software configuration, thereby to provide for personalized and/or generalized biomarker identification.

Abstract: Blepharometric data (data describing eyelid position as a function of time) is recorded and processed for the purposes of predicting a future risk and/or current occurrence of neurological events such as seizures. For example, in one embodiment, blepharometric data is recorded via infrared reflectance oculography spectacles, and processed in real time thereby to extract a set of blepharometric artifacts. Where those artifacts indicate prolonged spiking in blink calmness (for example, based on spiking in negative inter-event duration, or negative IED), an alert is able to be generated thereby to indicate that the subject is at risk of a seizure in a proximal time period. This provides an opportunity to implement mitigation measures, for example, to reduce the likelihood of the seizure manifesting, and/or to mitigate harm should the seizure occur.

Abstract: Devices and processing systems are configured to enable physiological event prediction based on blepharometric data analysis. For example, some embodiments provide methods and associated technology that enable retrospective analysis of blepharometric data driving subsequent hardware/software configuration, thereby to provide for personalized and/or generalized biomarker identification.

Abstract: The present invention relates, in various embodiments, to prediction of human subject states (e.g. physiological and/or psychological and/or neurological state) via a hybrid approach, which includes elements of AI-based classification and objective physiological analysis (such as blepharometric analysis). Embodiments are described by reference to applications in driver alertness monitoring. However, it will be appreciated that the technology is not limited as such, and has application in a broader range of context. For example, the technology is applicable to prediction of physiological states other than alertness level, and to implementation environments other than driver monitoring.

Abstract: Technology described herein relates to extended monitoring and analysis of subject neurological factors via blepharometric data collection, for example, including devices and processing systems configured to enable such extended monitoring. This may include hardware and software components deployed at subject locations (for example, in-vehicle monitoring systems, portable device monitoring systems, and so on), and cloud-based hardware and software (for example, cloud-based blepharometric data processing systems. The technology allows for user blepharometric data to be collected across a plurality of monitoring sessions, in some cases via different collection technologies, thereby to analyze changes over time. For example, this can assist in identifying risks of degenerative neurological conditions.

Abstract: Devices and processing systems are configured to enable physiological event prediction based on blepharometric data analysis. For example, some embodiments provide methods and associated technology that enable retrospective analysis of blepharometric data driving subsequent hardware/software configuration, thereby to provide for personalized and/or generalized biomarker identification.

Abstract: Blepharometric data (data describing eyelid position as a function of time) is recorded and processed for the purposes of predicting a future risk and/or current occurrence of neurological events such as seizures. For example, in one embodiment blepharometric data is recorded via infrared reflectance oculography spectacles, and processed in real time thereby to extract a set of blepharometric artifacts. Where those artifacts indicate prolonged spiking in blink calmness (for example based on spiking in negative inter-event duration, or negative IED), an alert is able to be generated thereby to indicate that the subject is at risk of a seizure in a proximal time period. This provides an opportunity to implement mitigation measures, for example to reduce the likelihood of the seizure manifesting, and/or to mitigate harm should the seizure occur.

Abstract: Technology is adapted to enable improved collection of involuntary eyelid movement parameters, including collection of eyelid movement parameters to support analysis of neurological factors. For example, this may include methods and systems configured to enable improved analysis of involuntary eyelid movement parameters, including diagnosis of subject neurological conditions and/or other subject attributes from analysis of involuntary eyelid movement parameters. Some embodiments relate to testing, which provide a standardized environment for collection of involuntary eyelid movement data thereby to reduce influence of variable factors, which affect involuntary eyelid movement. For example, the standardized environment influences the subject to adopt a controlled cognitive and/or physiological state, thereby to improve comparability of test results.

Abstract: Lower sampling rates have been found to provide sufficient data for use in the method of U.S. Pat. Nos. 7,071,831, 7,616,125 and 7,791,491. The method of determining drowsiness includes the steps of receiving eye movement data collected at sampling rates as low as 20 Hz. The data is preferentially interpolated to provide a data set at a higher sampling rate in the order of 500 Hz. For each data point, values of amplitude and velocity of eye movement and whether the measures relate to eyelid opening or closing are derived. An algorithm is then used to obtain values of the amplitude to velocity ratios of eyelid opening and closing and using these values in an algorithm for providing a measure of drowsiness. With this method eyelid and eye movement may be monitored using any suitable technology or sensor including video or digital camera technology to identify and measure the appropriate ocular movements.

Abstract: A composition comprising a C8 to C24 polyunsaturated fatty acid such as -linolenic or ester thereof, and terpinene-4-ol or derivative thereof. The composition has activity as a broad-spectrum antibacterial composition.

Abstract: A composition comprising a C8 to C24 polyunsaturated fatty acid such as-linolenic or ester thereof, and terpinene-4-ol or derivative thereof. The composition has activity as a broad-spectrum antibacterial composition.

Abstract: A WDM system comprising a first WDM module having a first multiplexer unit for multiplexing a WDM optical signal, a second WDM module having a first demultiplexer unit for demultiplexing the WDM optical signal, and wherein the system is arranged, in use, such that optical losses experienced by individual channels of the WDM optical signal in the first multiplexing unit and the first demultiplexing unit and optical losses experienced by the channels during un-amplified transmission between the first and second WDM modules are substantially balanced.

Abstract: A method of effecting failure protection switching in an optical network, the optical network comprising a ring structure carrying a bi-directional optical data signal, and a plurality of network hubs arranged in-line within the ring structure, each network hub being arranged, in use, to transmit and receive signals bi-directionally along the ring structure, the method comprising the steps of a) detecting a “no signal” at a primary pre-amplifier located at one of the network hubs and arranged to pre-amplify a primary optical signal received from a first direction along the ring structure b) shutting down the primary pre-amplifier and powering up a secondary pre-amplifier located at the one network hub and arranged to pre-amplify a redundant optical signal corresponding to the optical signal and received from the opposing direction along the ring structure.

Abstract: A hub structure for use in an optical network, the optical network comprising a ring structure carrying a bidirectional optical data signal and a plurality of hub structures arranged in-line within the ring structure, the optical data signal comprising primary and secondary path transmission signals having opposing transmission directions on the ring structure, the hub structure comprising a drop unit arranged, in a normal state, to drop and through-connect a primary receive path signal for further processing at the hub structure, and, in a protection state, to drop and through-connect a secondary receive path signal for further processing at the hub structure.

Abstract: An optical network hub structure comprising a WDM unit arranged in line with a fiber trunk carrying a bi-directional optical network signal to drop/add blocks of wavelengths destined to/originating from the network hub structure and to through connect other blocks of wavelengths, and at least one amplifier structure disposed in line on the fiber trunk at each side of the WDM unit, each amplifier structure comprising at least two propagation dependent optical junction elements, at least two optical paths optically connected in parallel between the two junction elements, and a first amplifier in only one of the optical paths, whereby a bi-directional, multiplexed optical signal comprising different blocks of wavelengths, each block of wavelengths having a specified propagation direction with respect to the amplifier structure, is, in use, uni-directionally amplified, whereby at each side of the WDM unit the optical network signal is, in use, uni-directionally amplified.

Abstract: An optical ring network structure comprising two or more network elements, and a single optical fiber connection between each pair of neighboring network elements for carrying an optical signal, wherein the ring network structure is arranged in a manner such that, in use, band allocation utilizing multiplexing on each single fiber connection is chosen in a manner such that groups of wavelengths for bi-directional data transfer and for bi-directional redundant data transfer for protection respectively are provided on each single fiber connection.