Patents by Inventor Trevor Brown

Trevor Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200335179
    Abstract: An embodiment of the invention provides a method for determining a patient-specific probability of disease. The method collects clinical parameters from a plurality of patients to create a training database. A fully unsupervised Bayesian Belief Network model is created using data from the training database; and, the fully unsupervised Bayesian Belief Network is validated. Clinical parameters are collected from an individual patient; and, such clinical parameters are input into the fully unsupervised Bayesian Belief Network model via a graphical user interface. The patient-specific probability of the healing rate of an acute traumatic wound is output from the fully unsupervised Bayesian Belief Network model and sent to the graphical user interface for use by a clinician in pre-operative planning. The fully unsupervised Bayesian Belief Network model is updated using the clinical parameters from the individual patient and the patient-specific probability of the healing rate of an acute traumatic wound.
    Type: Application
    Filed: July 7, 2020
    Publication date: October 22, 2020
    Inventors: Alexander Stojadinovic, Eric A. Elster, Doug K. Tadaki, John S. Eberhardt, III, Trevor Brown, Thomas A. Davis, Jonathan Forsberg, Jason Hawksworth
  • Patent number: 10752616
    Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain bicycloheteroaryl-heteroaryl-benzoic acid compounds of the following formula (for convenience, collectively referred to herein as “BHBA compounds”), which, inter alia, are (selective) retinoic acid receptor beta (RAR?) (e.g., RAR?2) agonists. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to (selectively) activate RAR? (e.g., RAR?2), to cause or promote neurite development, neurite outgrowth, and/or neurite regeneration, and in the treatment of diseases and conditions that are mediated by RAR? (e.g., RAR?2), that are ameliorated by the activation of RAR? (e.g., RAR?2), etc., including, e.g., neurological injuries such as spinal cord injuries.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: August 25, 2020
    Assignee: King's College London
    Inventors: Alan David Borthwick, Mark Trevor Mills, Jane Theresa Brown, Jonathan Patrick Thomas Corcoran, Maria Beatriz De Castro Vasconcelos Goncalves, Sarkis Barret Kalindjian
  • Patent number: 10726943
    Abstract: An embodiment of the invention provides a method for determining a patient-specific probability of disease. The method collects clinical parameters from a plurality of patients to create a training database. A fully unsupervised Bayesian Belief Network model is created using data from the training database; and, the fully unsupervised Bayesian Belief Network is validated. Clinical parameters are collected from an individual patient; and, such clinical parameters are input into the fully unsupervised Bayesian Belief Network model via a graphical user interface. The patient-specific probability of the healing rate of an acute traumatic wound is output from the fully unsupervised Bayesian Belief Network model and sent to the graphical user interface for use by a clinician in pre-operative planning. The fully unsupervised Bayesian Belief Network model is updated using the clinical parameters from the individual patient and the patient-specific probability of the healing rate of an acute traumatic wound.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: July 28, 2020
    Assignees: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY, DECISIONQ CORPORATION
    Inventors: Alexander Stojadinovic, Eric Elster, Doug K. Tadaki, John S. Eberhardt, III, Trevor Brown, Thomas A. Davis, Jonathan Forsberg, Jason Hawksworth
  • Patent number: 10669214
    Abstract: A method for manufacturing a cellular geopolymer product, which method comprises the steps: (a) forming an activated geopolymer premix by addition to a geopolymer premix of an activator compound that initiates a condensation reaction in the geopolymer premix; (b) casting the activated geopolymer premix in a desired configuration; and (c) generating gas bubbles in the activated geopolymer premix as the condensation reaction proceeds and the activated geopolymer premix stiffens to produce a self-supporting cellular structure; and (d) curing the self-supporting cellular structure to produce the cellular geopolymer product, wherein in step (c) the characteristics of the activated geopolymer premix and the reaction kinetics of the condensation reaction are controlled to achieve formation of the self-supporting cellular structure.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: June 2, 2020
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Kwesi Kurentsir Sagoe-Crentsil, David Alan Devenish, Genrietta Shapiro, Shiqin Yan, Leigh Gesthuizen, Trevor Brown
  • Publication number: 20200131165
    Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain bicycloheteroaryl-heteroaryl-benzoic acid compounds of the following formula (for convenience, collectively referred to herein as “BHBA compounds”), which, inter alia, are (selective) retinoic acid receptor beta (RAR?) (e.g., RAR?2) agonists. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to (selectively) activate RAR? (e.g., RAR?2), to cause or promote neurite development, neurite outgrowth, and/or neurite regeneration, and in the treatment of diseases and conditions that are mediated by RAR? (e.g., RAR?2), that are ameliorated by the activation of RAR? (e.g., RAR?2), etc., including, e.g., neurological injuries such as spinal cord injuries.
    Type: Application
    Filed: August 9, 2019
    Publication date: April 30, 2020
    Inventors: Alan David Borthwick, Mark Trevor Mills, Jane Theresa Brown, Jonathan Patrick Thomas Corcoran, Maria Beatriz De Castro Vasconcelos Goncalves, Sarkis Barret Kalindjian
  • Publication number: 20200049326
    Abstract: A luminaire for architectural, industrial and warehouse applications can be assembled using an extruded housing having curved sides connected by a cross member. Window openings in the curved sides can allow light to exit toward the sides of the luminaire while most of the light exits through a lens on the bottom. The extrusion can have channels and slots such that optical elements and an LED array can be slid into the housing and retained by endcaps. A housing cover can overlie a wireway while being held in place by screws creating a clamping force between the housing cover and fixture brackets retained within the housing. The luminaire can be suspended by the fixture brackets or by elements attached to the fixture brackets.
    Type: Application
    Filed: October 15, 2019
    Publication date: February 13, 2020
    Inventors: David Brown, Trevor Shaw, Jorge Alfredo Gomez Martinez, Ye Jin, Jiabin Yu, Zihai Lu
  • Publication number: 20190323687
    Abstract: A luminaire a small number of carefully designed extrusions is easily manufactured. The housing is formed by joining four pieces having a first extrusion profile. A second extrusion profile is used for the side and end covers. A third profile is used for access covers. The housing frames a lens, such as an acrylic sheet, and long lines of LEDs are positioned to shine directly into the side of the lens. A reflective layer on the lens directs all or some of the LED light out the luminaire's front, perhaps directing some light out the back. Strategically positioned diffusors ensure a pleasing lighting effect. The result is a very thin and light weight luminaire having a large surface area. The luminaire can be suspended by threaded nipples, by cables threaded through holes in the back, or by brackets screwed to threaded inserts.
    Type: Application
    Filed: May 7, 2019
    Publication date: October 24, 2019
    Inventors: Jorge Alfredo Gomez Martinez, David Brown, Ye Jin, Jiabin Yu, Zihai Lu, Trevor Shaw
  • Publication number: 20190291043
    Abstract: The present invention generally relates to methods and systems for capturing a Lewis acid gas (e.g., CO2). In some embodiments, the methods and systems utilize an ionic liquid incorporated into one or more electrochemical cells.
    Type: Application
    Filed: April 2, 2019
    Publication date: September 26, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Trevor Alan Hatton, Paul Brown, Sahag Voskian
  • Publication number: 20190264882
    Abstract: Luminaire housings for architectural, industrial and warehouse applications have extrusions with parallel flat sides connected by a cross member. The wireway can be enclosed by the extrusion's roof or by cover segments clamped over an open top extrusion. Wireway openings provide access to the wireway. Nuts slid into T-channels in the roof or cover segments provide for mounting or suspension via wall brackets, cables, and housing brackets. Threaded nipples accessible through the roof or cover segments provide for pendant stem mounting. Continuous run brackets can join housings end to end. Optical elements slid into slots and channels in the housing can be retained by end caps. A housing cover over the wireway can be clamped in place by screws threaded into fixture brackets retained within the housing. The housing grooves in the cover segments can slidably engage the extrusion until the cover segments are clamped in place.
    Type: Application
    Filed: May 7, 2019
    Publication date: August 29, 2019
    Inventors: Jorge Alfredo Gomez Martinez, David Brown, Ye Jin, Jiabin Yu, Zihai Lu, Trevor Shaw
  • Patent number: 10385044
    Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain bicycloheteroaryl-heteroaryl-benzoic acid compounds of the following formula (for convenience, collectively referred to herein as “BHBA compounds”), which, inter alia, are (selective) retinoic acid receptor beta (RAR?) (e.g., RAR?2) agonists. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to (selectively) activate RAR? (e.g., RARP?2), to cause or promote neurite development, neurite outgrowth, and/or neurite regeneration, and in the treatment of diseases and conditions that are mediated by RAR? (e.g., RAR?2), that are ameliorated by the activation of RAR? (e.g., RAR?2), etc., including, e.g., neurological injuries such as spinal cord injuries.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: August 20, 2019
    Assignee: King's College London
    Inventors: Alan David Borthwick, Mark Trevor Mills, Jane Theresa Brown, Jonathan Patrick Thomas Corcoran, Maria Beatriz De Castro Vasconcelos Goncalves, Sarkis Barret Kalindjian
  • Publication number: 20190249500
    Abstract: A flexible coupling for coupling sections of a downhole tubing string is provided. The flexible coupling has a central section with first and second ends, each end having a contact surface and a first part of a pivoting connector, the contact surface extending radially outward relative to the first part of the pivoting connector. The flexible coupling also has first and second coupling sections pivotally coupled to the first and second ends of the central section. Each of the first and second coupling sections have a tubing string attachment at a first end, a second part of the pivoting connector at a second end, and a contact surface at the second end, the contact surface extending radially outward relative to the second part of the pivoting connector. Pivotal movement of the first and second coupling sections relative to the central section is limited by engagement between the contact surfaces.
    Type: Application
    Filed: February 5, 2019
    Publication date: August 15, 2019
    Inventors: Douglas ROSTEN, Derek KITCHEN, Jeffrey GOLINOWSKI, Trevor ROSTEN, Cody BROWN
  • Patent number: 10331679
    Abstract: A method and apparatus for providing a recommendation for learning about an interest are disclosed. For example, the method receives a query for a recommendation for one or more articles for learning about an interest, determines whether the interest of the user is in a list of interests, wherein each particular interest is an interest for which a database contains at least one article for learning about the particular interest, wherein the database is used for storing for each particular article: the particular article and a normalized relationship score for the interest, retrieves from the database, one or more articles having the normalized relationship score related to the interest when the interest is in the list of interests, and presents the recommendation to an endpoint device of the user, wherein the recommendation comprises the one or more articles related to the interest that are retrieved.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: June 25, 2019
    Assignee: AT&T Intellectual Property I, L.P.
    Inventors: Bryan Strassner, Allen Brown, Michael Lemen, Trevor Lovett, Douglas McCullough, Matthew McEuen
  • Patent number: 10286355
    Abstract: The present invention generally relates to methods and systems for capturing a Lewis acid gas (e.g., CO2). In some embodiments, the methods and systems utilize an ionic liquid incorporated into one or more electrochemical cells.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: May 14, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Trevor Alan Hatton, Paul Brown, Sahag Voskian
  • Publication number: 20190023425
    Abstract: Artificially directing a plurality of space-borne natural bodies to a target accretion region, such that gravitational forces amongst the plurality of space-borne natural bodies within the target accretion region produces an agglomerated space-borne body comprised of at least portions of the plurality of space-borne natural bodies. These teachings will accommodate use of a variety of space-borne natural bodies including asteroids, comets, and moons.
    Type: Application
    Filed: June 5, 2018
    Publication date: January 24, 2019
    Inventor: Trevor Brown
  • Patent number: 10127088
    Abstract: Socket scheduling modes may prevent non-uniform memory access effects from negatively affecting performance of synchronization mechanisms utilizing hardware transactional memory. Each mode may indicate whether a thread may execute a critical section on a particular socket. For example, under transitional lock elision, locks may include a mode indicating whether threads may acquire or elide the lock on a particular socket. Different modes may be used alternately to prevent threads from starving. A thread may only execute a critical section on a particular socket if allowed by the current mode. Otherwise, threads may block until allowed to execute the critical section, such as after the current mode changes. A profiling session may, for a running workload, iterate over all possible modes, measuring statistics pertaining to the execution of critical sections (e.g., the number of lock acquisitions and/or elisions), to determine the best performing modes for the particular workload.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: November 13, 2018
    Assignee: Oracle Inrternational Corporation
    Inventors: Alex Kogan, Victor M. Luchangco, Yosef Lev, Trevor Brown
  • Publication number: 20170075720
    Abstract: Socket scheduling modes may prevent non-uniform memory access effects from negatively affecting performance of synchronization mechanisms utilizing hardware transactional memory. Each mode may indicate whether a thread may execute a critical section on a particular socket. For example, under transitional lock elision, locks may include a mode indicating whether threads may acquire or elide the lock on a particular socket. Different modes may be used alternately to prevent threads from starving. A thread may only execute a critical section on a particular socket if allowed by the current mode. Otherwise, threads may block until allowed to execute the critical section, such as after the current mode changes. A profiling session may, for a running workload, iterate over all possible modes, measuring statistics pertaining to the execution of critical sections (e.g., the number of lock acquisitions and/or elisions), to determine the best performing modes for the particular workload.
    Type: Application
    Filed: September 12, 2016
    Publication date: March 16, 2017
    Inventors: Alex Kogan, Victor M. Luchangco, Yosef Lev, Trevor Brown
  • Publication number: 20150351552
    Abstract: A chair includes a first side member, a second side member, a back cross member, a first flex member, and a second flex member. The first side member supports a first side of the chair and the second side member supports a second side of the chair. The back cross member is situated between the first side member and the second side member and rotates relative to the first side member and the second side member. The first flex member is coupled to the first side member and the back cross member and twists as the back cross member rotates relative to the first side member and the second side member. The second flex member is coupled to the second side member and the back cross member and twists as the back cross member rotates relative to the first side member and the second side member.
    Type: Application
    Filed: June 4, 2015
    Publication date: December 10, 2015
    Inventors: Trevor Brown, Jeremy Foreman
  • Publication number: 20140238265
    Abstract: A method for manufacturing a cellular geopolymer product, which method comprises the steps: (a) forming an activated geopolymer premix by addition to a geopolymer premix of an activator compound that initiates a condensation reaction in the geopolymer premix; (b) casting the activated geopolymer premix in a desired configuration; and (c) generating gas bubbles in the activated geopolymer premix as the condensation reaction proceeds and the activated geopolymer premix stiffens to produce a self-supporting cellular structure; and (d) curing the self-supporting cellular structure to produce the cellular geopolymer product, wherein in step (c) the characteristics of the activated geopolymer premix and the reaction kinetics of the condensation reaction are controlled to achieve formation of the self-supporting cellular structure.
    Type: Application
    Filed: September 28, 2012
    Publication date: August 28, 2014
    Inventors: Kwesi Kurentsir Sagoe-Crentsil, David Alan Devenish, Genrietta Shapiro, Shiqin Yan, Leigh Gesthuizen, Trevor Brown
  • Patent number: 8672606
    Abstract: A gas turbine engine includes a compressor having first annular connection structure at a forward end portion of an air inlet housing of the compressor. The gas turbine engine may also include intake ducting having second annular connection structure adjacent a central passage of the intake ducting. The first annular connection structure and the second annular connection structure may form at least part of an interface between the air inlet housing and the intake ducting during operation of the gas turbine engine. The first and second annular connection structures may have shapes allowing the first annular connection structure to be moved through and beyond the second annular connection structure in a forward direction, the forward direction being opposite a direction of compressed air flow in the compressor during operation.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: March 18, 2014
    Assignee: Solar Turbines Inc.
    Inventors: Gabriel James Glynn, Charles Cornelius, Ian Trevor Brown, Daniel James Doll, Jason Michael Robertson
  • Patent number: D740044
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: October 6, 2015
    Assignee: HNI Technologies Inc.
    Inventors: Trevor Brown, Jeremy Foreman