Patents by Inventor Trevor Carlton
Trevor Carlton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8574618Abstract: A bio-absorbable stand-alone film is derived at least in part from fatty acids. The bio-absorbable stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. The stand-alone film has one or more perforations or depressions formed therein. Corresponding methods of making the bio-absorbable stand-alone film with one or more perforations or depressions include molding, cutting, carving, puncturing or otherwise suitable methods to create the perforations or depressions in the bio-absorbable stand-alone film. The resulting stand-alone film is bioabsorbable.Type: GrantFiled: November 21, 2012Date of Patent: November 5, 2013Assignee: Atrium Medical CorporationInventors: Steve A. Herweck, Thomas M. Swanick, Joseph Ferraro, Paul Martakos, Lisa Rogers, Theodore Karwoski, Keith M. Faucher, Philip McNamara, Roger Labrecque, Suzanne Conroy, Trevor Carlton
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Patent number: 8367099Abstract: A bio-absorbable stand-alone film is derived at least in part from fatty acids. The bio-absorbable stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. The stand-alone film has one or more perforations or depressions formed therein. Corresponding methods of making the bio-absorbable stand-alone film with one or more perforations or depressions include molding, cutting, carving, puncturing or otherwise suitable methods to create the perforations or depressions in the bio-absorbable stand-alone film. The resulting stand-alone film is bioabsorbable.Type: GrantFiled: September 22, 2006Date of Patent: February 5, 2013Assignee: Atrium Medical CorporationInventors: Steve A. Herweck, Thomas M. Swanick, Joseph Ferraro, Paul Martakos, Lisa Rogers, Theodore Karwoski, Keith M. Faucher, Philip McNamara, Roger Labrecque, Suzanne Conroy, Trevor Carlton
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Patent number: 8308684Abstract: A non-polymeric or biological coating applied to a radially expandable interventional medical device in a collapsed, wrapped, or folded configuration, the coating applied within at least one fold. Properties of the coating material applied to the medical device are adjusted or varied to result in a desired combination of coverage of the surface of the medical device, drug loading, and coating thickness. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device.Type: GrantFiled: May 6, 2011Date of Patent: November 13, 2012Assignee: Atrium Medical CorporationInventors: Steve A. Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton, Lisa Rogers, Joseph Ferraro
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Patent number: 8021331Abstract: A non-polymeric or biological coating applied to a radially expandable interventional medical device in a collapsed, wrapped, or folded configuration. Properties of the coating material applied to the medical device are adjusted or varied to result in a desired combination of coverage of the surface of the medical device, drug loading, and coating thickness. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device.Type: GrantFiled: October 14, 2005Date of Patent: September 20, 2011Assignee: Atrium Medical CorporationInventors: Steve A. Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton, Lisa Rogers, Joseph Ferraro
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Publication number: 20110213302Abstract: A non-polymeric or biological coating applied to a radially expandable interventional medical device in a collapsed, wrapped, or folded configuration, the coating applied within at least one fold. Properties of the coating material applied to the medical device are adjusted or varied to result in a desired combination of coverage of the surface of the medical device, drug loading, and coating thickness. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device.Type: ApplicationFiled: May 6, 2011Publication date: September 1, 2011Inventors: Steve A. Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton, Lisa Rogers, Joseph Ferraro
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Patent number: 7947015Abstract: A non-polymeric or biological coating applied to radially expandable medical delivery device provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The delivery device is expanded using the pressure of an inflation fluid. After expanding the delivery device to a pre-determined size and shape, the inflation fluid weeps through the porous surface of the delivery device. The coating releases the delivery device and floats on the inflation fluid until bonding to the tissue due to its affinity for the tissue. Once the coating bonds or affixes to the tissue, through an absorption mechanism by the tissue cells of the coating material, the coating and any therapeutics contained therein are delivered to the tissue. The fluid can contain a therapeutic agent, or can be otherwise biocompatible and/or inert.Type: GrantFiled: May 18, 2007Date of Patent: May 24, 2011Assignee: Atrium Medical CorporationInventors: Steve A. Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton
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Publication number: 20100034867Abstract: The present inventions provide various embodiments of medical devices coated with a therapeutic coating comprising a mTOR targeting compound and a calcineurin inhibitor, and methods of applying said coatings. In various aspects, the therapeutic coating comprises a bio-absorbable carrier component at least partially formed of a cellular uptake inhibitor and a cellular uptake enhancer, a mTOR targeting compound and a calcineurin inhibitor. In various aspects, the present invention provides for controlled delivery, which is at least partially characterized by total and relative amounts of a cellular uptake inhibitor and cellular uptake enhancer in a bio-absorbable carrier component.Type: ApplicationFiled: April 28, 2006Publication date: February 11, 2010Applicant: ATRIUM MEDICAL CORPORATIONInventors: Steve A. Herweck, Paul Martakos, Geoffrey Moodie, Theodore Karwoski, Trevor Carlton
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Publication number: 20100004738Abstract: The present inventions provide various embodiments of methods for one or more of treating vascular injury, neointima proliferation and/or local inflammation in a mammal by locally administering therapeutic compound comprising a mTOR targeting compound and a calcineurin inhibitor. In various aspects, the therapeutic compound comprises a bio-absorbable carrier component carrier component at least partially formed of a cellular uptake inhibitor and a cellular uptake enhancer, a mTOR targeting compound and a calcineurin inhibitor. In various aspects, the present invention provides for controlled delivery, which is at least partially characterized by total and relative amounts of a cellular uptake inhibitor and cellular uptake enhancer in a bio-absorbable carrier component.Type: ApplicationFiled: April 28, 2006Publication date: January 7, 2010Applicant: ATRIUM MEDICAL CORPORATIONInventors: Steve A. Herweck, Paul Martakos, Geoffrey Moodie, Theodore Karwoski, Trevor Carlton
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Patent number: 7572245Abstract: A non-polymeric or biological coating applied to radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.Type: GrantFiled: September 15, 2004Date of Patent: August 11, 2009Assignee: Atrium Medical CorporationInventors: Steve A. Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton
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Publication number: 20080015500Abstract: A non-polymeric or biological coating applied to radially expandable medical delivery device provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The delivery device is expanded using the pressure of an inflation fluid. After expanding the delivery device to a pre-determined size and shape, the inflation fluid weeps through the porous surface of the delivery device. The coating releases the delivery device and floats on the inflation fluid until bonding to the tissue due to its affinity for the tissue. Once the coating bonds or affixes to the tissue, through an absorption mechanism by the tissue cells of the coating material, the coating and any therapeutics contained therein are delivered to the tissue. The fluid can contain a therapeutic agent, or can be otherwise biocompatible and/or inert.Type: ApplicationFiled: May 18, 2007Publication date: January 17, 2008Applicant: ATRIUM MEDICAL CORPORATIONInventors: Steve Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton
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Publication number: 20070084144Abstract: A method for the sterilization and packaging of a chemically sensitive medical device is provided. The chemically sensitive medical device has a coating derived from fish oil, a vitamin E compound or a combination thereof. The packaging pouch for the chemically sensitive medical device comprises a non-permeable chamber and a gas-permeable header. The sterilizing agent is administered to the packaged chemically sensitive medical device at a temperature of between about 20° C. and 40° C.Type: ApplicationFiled: September 22, 2006Publication date: April 19, 2007Applicant: ATRIUM MEDICAL CORPORATIONInventors: Roger Labrecque, Suzanne Conroy, Keith Faucher, Thomas Swanick, Paul Martakos, Theodore Karwoski, Steve Herweck, Trevor Carlton
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Publication number: 20070071798Abstract: A bio-absorbable stand-alone film is derived at least in part from fatty acids. The bio-absorbable stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. The stand-alone film has one or more perforations or depressions formed therein. Corresponding methods of making the bio-absorbable stand-alone film with one or more perforations or depressions include molding, cutting, carving, puncturing or otherwise suitable methods to create the perforations or depressions in the bio-absorbable stand-alone film. The resulting stand-alone film is bioabsorbable.Type: ApplicationFiled: September 22, 2006Publication date: March 29, 2007Applicant: ATRIUM MEDICAL CORPORATIONInventors: Steve Herweck, Thomas Swanick, Joseph Ferraro, Paul Martakos, Lisa Rogers, Theodore Karwoski, Keith Faucher, Philip McNamara, Roger Labrecque, Suzanne Conroy, Trevor Carlton
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Publication number: 20060112536Abstract: A non-polymeric or biological coating applied to a radially expandable interventional medical device in a collapsed, wrapped, or folded configuration. Properties of the coating material applied to the medical device are adjusted or varied to result in a desired combination of coverage of the surface of the medical device, drug loading, and coating thickness. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device.Type: ApplicationFiled: October 14, 2005Publication date: June 1, 2006Applicant: ATRIUM MEDICAL CORPORATIONInventors: Steve Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton, Lisa Rogers, Joseph Ferraro
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Publication number: 20050113687Abstract: A non-polymeric or biological coating applied to porous radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.Type: ApplicationFiled: September 15, 2004Publication date: May 26, 2005Inventors: Steve Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton
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Publication number: 20050106206Abstract: A non-polymeric or biological coating applied to radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.Type: ApplicationFiled: September 15, 2004Publication date: May 19, 2005Inventors: Steve Herweck, Paul Martakos, Geoffrey Moodie, Roger Labrecque, Theodore Karwoski, Trevor Carlton