Patents by Inventor Trevor Collingwood

Trevor Collingwood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR MODIFICATION OF A HLA LOCUS
    Publication number: 20210054046
    Abstract: Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.
    Type: Application
    Filed: November 6, 2020
    Publication date: February 25, 2021
    Inventors: Trevor Collingwood, Laurence J.N. Cooper, Philip D. Gregory, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar, Andreas Reik, Fyodor Urnov
  • Modulation of stem cells using zinc finger proteins
    Patent number: 10888589
    Abstract: Methods and compositions for modifying stem cells using one or more ZFPs are disclosed. Such methods and compositions are useful for facilitating processes such as, for example, dedifferentiating cells, differentiating stem cells into the desired phenotype, propagating stem cells and/or facilitating cloning.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: January 12, 2021
    Assignee: Sangamo Therapeutics, Inc.
    Inventors: Alan P. Wolffe, Michael Moore, Timothy Farries, Trevor Collingwood, Fyodor Urnov
  • Methods and compositions for modification of a HLA locus
    Patent number: 10858416
    Abstract: Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: December 8, 2020
    Assignees: Sangamo Therapeutics, Inc., Board of Regents, The University of Texas System
    Inventors: Trevor Collingwood, Laurence J. N. Cooper, Philip D. Gregory, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar, Andreas Reik, Fyodor Urnov
  • METHODS AND COMPOSITIONS FOR MODIFICATION OF A HLA LOCUS
    Publication number: 20180319864
    Abstract: Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.
    Type: Application
    Filed: July 17, 2018
    Publication date: November 8, 2018
    Inventors: Trevor Collingwood, Laurence J.N. Cooper, Philip D. Gregory, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar, Andreas Reik, Fyodor Urnov
  • Methods and compositions for modification of a HLA locus
    Patent number: 10072062
    Abstract: Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: September 11, 2018
    Assignees: Sangamo Therapeutics, Inc., Board of Regents, The University of Texas Systems
    Inventors: Trevor Collingwood, Laurence J. N. Cooper, Philip D. Gregory, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar, Andreas Reik, Fyodor Urnov
  • Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
    Patent number: 9890395
    Abstract: Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: February 13, 2018
    Assignee: Sangamo Therapeutics, Inc.
    Inventors: Trevor Collingwood, Gregory J. Cost
  • MODULATION OF STEM CELLS USING ZINC FINGER PROTEINS
    Publication number: 20170224741
    Abstract: Methods and compositions for modifying stem cells using one or more ZFPs are disclosed. Such methods and compositions are useful for facilitating processes such as, for example, dedifferentiating cells, differentiating stem cells into the desired phenotype, propagating stem cells and/or facilitating cloning.
    Type: Application
    Filed: April 13, 2017
    Publication date: August 10, 2017
    Inventors: Alan P. Wolffe, Michael Moore, Timothy Farries, Trevor Collingwood, Fyodor Urnov
  • Modulation of stem cells using zinc finger proteins
    Patent number: 9624509
    Abstract: Methods and compositions for modifying stem cells using one or more ZFPs are disclosed. Such methods and compositions are useful for facilitating processes such as, for example, dedifferentiating cells, differentiating stem cells into the desired phenotype, propagating stem cells and/or facilitating cloning.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: April 18, 2017
    Assignee: SANGAMO BIOSCIENCES, INC.
    Inventors: Alan P. Wolffe, Michael Moore, Timothy Farries, Trevor Collingwood, Fyodor Urnov
  • METHODS AND COMPOSITIONS FOR INACTIVATING ALPHA 1,6 FUCOSYLTRANSFERASE (FUT8) GENE EXPRESSION
    Publication number: 20160194665
    Abstract: Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
    Type: Application
    Filed: March 24, 2016
    Publication date: July 7, 2016
    Inventors: Trevor Collingwood, Gregory J. Cost
  • Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
    Patent number: 9322036
    Abstract: Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: April 26, 2016
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Trevor Collingwood, Gregory J. Cost
  • METHODS AND COMPOSITIONS FOR MODIFICATION OF A HLA LOCUS
    Publication number: 20150252094
    Abstract: Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.
    Type: Application
    Filed: January 5, 2015
    Publication date: September 10, 2015
    Inventors: Trevor Collingwood, Laurence J.N. Cooper, Philip D. Gregory, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar, Andreas Reik, Fyodor Urnov
  • Methods and compositions for modification of a HLA locus
    Patent number: 8945868
    Abstract: Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: February 3, 2015
    Assignees: Sangamo BioSciences, Inc., Board of Regents, The University of Texas Systems
    Inventors: Trevor Collingwood, Laurence J. N. Cooper, Philip D. Gregory, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar, Andreas Reik, Fyodor Urnov
  • METHODS AND COMPOSITIONS FOR INACTIVATING ALPHA 1,6 FUCOSYLTRANSFERASE (FUT8) GENE EXPRESSION
    Publication number: 20140273097
    Abstract: Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
    Type: Application
    Filed: May 28, 2014
    Publication date: September 18, 2014
    Applicant: Sangamo BioSciences, Inc.
    Inventors: Trevor Collingwood, Gregory J. Cost
  • MODULATION OF STEM CELLS USING ZINC FINGER PROTEINS
    Publication number: 20140234970
    Abstract: Methods and compositions for modifying stem cells using one or more ZFPs are disclosed. Such methods and compositions are useful for facilitating processes such as, for example, dedifferentiating cells, differentiating stem cells into the desired phenotype, propagating stem cells and/or facilitating cloning.
    Type: Application
    Filed: May 5, 2014
    Publication date: August 21, 2014
    Applicant: Sangamo BioSciences, Inc.
    Inventors: Alan P. Wolffe, Michael Moore, Timothy Farries, Trevor Collingwood, Fyodor Urnov
  • Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
    Patent number: 8772025
    Abstract: Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: July 8, 2014
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Trevor Collingwood, Gregory J. Cost
  • Modulation of stem cells using zinc finger proteins
    Patent number: 8735153
    Abstract: Methods and compositions for modifying stem cells using one or more ZFPs are disclosed. Such methods and compositions are useful for facilitating processes such as, for example, dedifferentiating cells, differentiating stems cells into the desired phenotype, propagating stem cells and/or facilitating cloning.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: May 27, 2014
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Michael Moore, Timothy Farries, Trevor Collingwood, Fyodor Urnov, Elizabeth J. Wolffe
  • Methods and compositions for generation of Bax-and Bak-deficient cell lines
    Patent number: 8597912
    Abstract: Disclosed herein are methods and compositions for generation of Bak- and/or Bax-deficient cell lines using engineered nucleases.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: December 3, 2013
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Trevor Collingwood, Philip D. Gregory
  • Nucleic acid encoding a zinc finger that recognizes the sodium channel Nav 1.8 (PN3) gene
    Patent number: 8466267
    Abstract: A variety of zinc finger proteins (ZFPs) and methods utilizing such proteins are provided for use in treating neuropathic pain. ZFPs that bind to a target site in genes that are aberrantly expressed in subjects having neuropathic pain are described. In addition, ZFPs that bind to a target site in genes expressed at normal levels in subjects experiencing neuropathic pain, modulation of whose expression results in decreased pain perception, are also provided. For example, genes that are over-expressed in the dorsal root ganglia (DRG) of pain patients (e.g., VR1, TRKA and/or Nav1.8) can be repressed, whereas genes that are under-expressed in the same populations can be activated.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: June 18, 2013
    Assignee: Sangamo Biosciences, Inc.
    Inventor: Trevor Collingwood
  • METHODS AND COMPOSITIONS FOR MODIFICATION OF A HLA LOCUS
    Publication number: 20120060230
    Abstract: Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.
    Type: Application
    Filed: July 21, 2011
    Publication date: March 8, 2012
    Inventors: Trevor Collingwood, Laurence J.N. Cooper, Philip D. Gregory, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar, Andreas Reik, Fyodor Urnov
  • Targeted modification of chromatin structure
    Patent number: 8071370
    Abstract: Methods and compositions for targeted modification of chromatin structure, within a region of interest in cellular chromatin, are provided. Such methods and compositions are useful for facilitating processes such as, for example, transcription and recombination, that require access of exogenous molecules to chromosomal DNA sequences.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: December 6, 2011
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Alan P. Wolffe, Elizabeth J. Wolffe, legal representative, Trevor Collingwood, Philip D. Gregory, Andrew Snowden, Fyodor Urnov