Abstract: A tubular prosthesis comprises a tubular graft; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the first group of apexes being pivotally attached to the tubular graft so as to form a plurality of circumferentially arranged hinges about which the stent can pivot so that the second group of apexes can move between a position where they are inside the tubular graft and a position where they are outside the tubular graft.

Abstract: An endoluminal prosthesis for use in the ascending aorta is disclosed. The prosthesis includes a tubular graft material having an outer surface and an inner surface, a support structure coupled to the graft material, and a plurality of anchors extending from a proximal end of the support structure. Each anchor is curved outwardly such that a middle portion of the anchor extends further outwardly than a proximal portion of the anchor and a distal portion of the anchor such that the anchors conform to the shape of the aortic root. A hook extends outwardly from a proximal end of each anchor to engage the annulus of the aortic valve. The proximal end of the support structure and graft material is disposed adjacent the sinotubular junction.

Abstract: A method includes deploying a fenestration segment stent-graft into a main vessel such that a fenestration section of the fenestration segment stent-graft covers a first branch vessel emanating from the main vessel. The fenestration segment stent-graft includes a proximal section, a distal section, and the fenestration section attached to and between the proximal section and the distal section. The fenestration section has a greater resistance to tearing than the proximal section and the distal section facilitating formation of a collateral opening aligned with the branch vessel in the fenestration section.

Abstract: A covered stent comprises a substrate, a stent adapted to be placed in a lumen of a human body, where the stent has portions interwoven in the substrate, and encapsulation encapsulating the substrate and the portions of the stent interwoven in the substrate and forming a tubular graft member.

Abstract: When a main stent-graft is placed in a vessel of a patient and a branch vessel is blocked by the main stent-graft, a RF plasma catheter is used to cut out a portion of the graft cloth of the main-stent graft adjacent to an ostium of the branch vessel to be perfused. To ameliorate possible adverse effects associated with the use of the RF plasma catheter, e.g., creation of coagulum, (desiccated, coagulated blood) or perhaps a cut stent strut, a special process using saline flushing, a novel RF plasma catheter with an insulated tip, or a combination of the two is used.

Abstract: An endostapler delivery system includes a biasing mechanism to offset or counter forces generated by a stapling device and therefore prevent the stapling device from moving during the firing of the staple. The delivery system includes a catheter having at least one lumen extending there through for receiving the stapling device. The biasing mechanism is an expandable biasing cage having a dome or semi-circular expanded shape provided at the distal portion of the catheter. When expanded, the biasing cage does not block or occlude a vessel, thereby allowing blood flow to continue during the stapling procedure. The biasing cage may include a plurality of ribbons or strands that extend generally parallel to the blood flow when expanded in situ, a mesh or braided structure, or a plurality of ribbons or strands that extend generally parallel to the blood flow when expanded in situ and a mesh or braided structure placed over the plurality of ribbons.

Abstract: An endostapler delivery system includes a biasing mechanism to offset or counter forces generated by a stapling device and therefore prevent the stapling device from moving during the firing of the staple. The delivery system includes a catheter having at least one lumen extending there through for receiving the stapling device. The biasing mechanism is an expandable biasing cage having a dome or semi-circular expanded shape provided at the distal portion of the catheter. When expanded, the biasing cage does not block or occlude a vessel, thereby allowing blood flow to continue during the stapling procedure. The endostapler delivery system further includes a steering wire that can be used to bend the catheter shaft.

Abstract: A stent graft with pins, a stent graft including a tubular graft having a perimeter and a central axis; at least one stent ring operably connected about the perimeter, the stent ring having a plurality of struts connected in a sinusoidal pattern, at least one of the plurality of struts having a hole; and a pin having a free end. The pin is secured in the hole with the free end directed outwardly from the central axis.

Abstract: An anchoring balloon of an anchoring balloon catheter is advanced through the branch vessel to be adjacent to the main stent graft within a main vessel. The anchoring balloon is inflated to center an inner member of the anchoring balloon catheter within the branch vessel and to anchor the anchoring balloon within the branch vessel. A needle assembly is advanced to pierce the graft material of the main stent graft with a needle forming a needle hole in the graft material. A dilator assembly is advanced to dilate the needle hole with a dilator.

Abstract: A tubular prosthesis comprises a tubular member having raised portions, which can be formed from and be part of the tubular member. The raised portions form a chamber or discrete space in a body passageway or lumen between the prosthesis and a portion of the passageway or lumen wall in which it is placed. A substance is delivered to the chamber to assist the prosthesis placement. The substance can comprise one or more substances that can enhance the seal and/or fixation characteristics between the prosthesis the passageway wall and/or provide therapeutic benefit. In another embodiment, the raised portions can be collars secured to the tubular member and in yet a further embodiment the raised portions can comprise inflatable collars.

Abstract: A stent graft system with injection tube, the stent graft system for injecting an agent into an aneurysmal sac from an external pressurized source, including a stent graft having a permeable graft and a framework supporting the permeable graft; and an injection tube connected to the stent graft adjacent to the permeable graft, the injection tube having a plurality of holes adjacent to the permeable graft. The external pressurized source forces the agent through the plurality of holes into the aneurysmal sac.

Abstract: One or more markers or sensors are positioned in the vasculature of a patient to facilitate determining the location, configuration, and/or orientation of a vessel or certain aspects thereof (e.g., a branch vessel), determining the location, configuration and/or orientation of a endovascular devices prior to and during prosthesis deployment as well as the relative position of portions of the vasculature and devices, generating an image of a virtual model of a portion of one or more vessels (e.g., branch vessels) or devices, and/or formation of one or more openings in a tubular prosthesis in situ to allow branch vessel perfusion when the prosthesis is placed over one or more branch vessels in a patient (e.g., when an aortic abdominal artery stent-graft is fixed to the aorta superior to the renal artery ostia).

Abstract: A primary and branch graft deployment delivery system (70) comprises a primary graft (72) having a branch port opening or member (75), a retractable primary sheath containing the primary graft, an outer tube (60) within the retractable primary sheath and within the primary graft, an inner tube (61) within the outer tube, a cap (54 or 71) coupled to the inner tube and configured to retain at least a portion of a proximal area (73) of the primary graft in a radially compressed configuration. The system further comprises a branch graft (89) advanceable through the branch graft port member and further comprising a snap connector member (90) associated with the branch graft, the snap connector member being configured to frictionally engage the port member, the engagement of the snap connector to the port member forms a connection between the proximal end of the branch graft and the primary graft.

Abstract: An endoluminal prosthesis including a tubular graft having a proximal end and a distal end; a suprarenal spring stent operably connected to the proximal end, the suprarenal spring stent having suprarenal positive apices and suprarenal negative apices connected in a sinusoidal ring pattern by suprarenal struts; and a sealing spring stent operably connected to the tubular graft, the sealing spring stent having sealing positive apices, sealing negative apices, and intermediate sealing negative apices connected in a ring pattern, the sealing negative apices alternating with the intermediate sealing negative apices between adjacent sealing positive apices, the sealing positive apices being connected to the sealing negative apices by sealing struts, and the sealing positive apices being connected to the intermediate sealing negative apices by intermediate sealing struts. The suprarenal positive apices are axially aligned with the intermediate sealing negative apices.

Abstract: A delivery system for an endoprosthesis includes a spindle having a spindle body and spindle pins extending radially outward from the spindle body. The delivery system further comprises a tip comprising a sleeve, the spindle pins extending from the spindle body toward the sleeve. The endoprosthesis includes a proximal anchor stent ring having spindle pin catches and anchor pins. The spindle pins of the spindle extend into the spindle pin catches and the sleeve radially constrains the anchor pins.

Abstract: A proximal anchor stent ring of an endoprosthesis includes proximal apexes, distal apexes, struts extending between the proximal apexes and the distal apexes, and anchor pins. The struts, the proximal apexes, and the distal apexes define an imaginary cylindrical surface. A pair of the anchor pins is located on the struts adjacent each of the proximal apexes, the anchor pins extending inwards from inside surfaces of the struts and protruding from the struts radially outward from the cylindrical surface. By locating the anchor pins inwards, the delivery profile of the proximal anchor stent ring is minimized.

Abstract: A device and method for controlling the positioning of one or more flexible stent graft fenestrations are disclosed. The stent graft may be for repair of an aneurysm proximate a branch vessel. The stent graft includes a primary graft having an anchoring device, a graft material forming a central lumen and at least one flexible fenestration in a side wall thereof. A fenestration positioning member extends within the stent graft central lumen and has a distal end removably attached to the stent graft proximate the at least one flexible fenestration. The fenestration positioning member may include a tubular member having a wire extending there through, wherein a sidewall of the tubular member includes an aperture through which a loop of the wire extends and removably attaches to the fenestration.

Abstract: A stent graft and method for positioning and deploying the stent graft within a vessel system that includes a main vessel and a branch vessel emanating from the main vessel. The stent graft includes a tubular shaped main body formed from graft material, a branch opening (aperture)(ring) in the graft material of the main body whose position can be varied. A tubular shaped branch graft can extend from the main graft. A side wall of the main body may be configured as a series of connected annular corrugations or pleats, and coupled to the main body to define and provide variable positioning of its branch opening (aperture).

Abstract: A system and method of branch vessel marking including a branch vessel marking system for a branch vessel off a main vessel, the branch vessel having an ostium and a branch vessel centerline, the system having a catheter 105 and a balloon 110 operably attached to the catheter 105. The balloon 110 has a proximal portion 111 and a distal portion 109, a long axis 112, and a coil 114 disposed on the long axis 112. Differential expansion of the distal portion 109 relative to the proximal portion 111 when the distal portion 109 is inflated in the branch vessel and the proximal portion 111 is inflated in the main vessel indicates the ostium of the branch vessel and locates the coil 114 on the branch vessel centerline.

Abstract: A method of using a delivery system includes advancing a stent to be located within an ostium of a vessel; advancing a basket actuation button of a handle to deploy a basket of the basket assembly; moving the basket into engagement with a parent vessel, the basket having a larger diameter than a diameter of the ostium; deploying the stent within an ostial lesion of the vessel; and contracting the basket.