Patents by Inventor Trevor H. Adams

Trevor H. Adams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic kits useful for selectively detecting microorganisms in samples
    Patent number: 5776694
    Abstract: The present invention relates, in general, to diagnostic kits for selectively detecting a prokaryotic microorganism and a eukaryotic microorganism in a sample wherein the cells of such microorganisms are lysed by combining the sample with a lysis solution and contacting the nucleic acid released from the microorganisms with selective nucleic acid probes through hybridization techniques. The present invention can be used for detecting microorganisms associated with vaginal disorders, e.g., Gardnerella vaginalis, Trichomonas vaginalis and Candida albicans. These kits may be used in a medical practitioner's private office or in a more structured clinical environment, such as a hospital, a commercial clinical microbiology laboratory or the like.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: July 7, 1998
    Assignee: Becton Dickinson Company
    Inventors: Diana K. Sheiness, Trevor H. Adams, Michael R. Stamm, Gerard A. Cangelosi, Theresa B. Britschgi, Connie K. Dix
  • Methods for selectively detecting microorganisms associated with vaginal infections in complex biological samples
    Patent number: 5700636
    Abstract: The present invention relates, in general, to methods for selectively detecting a prokaryotic microorganism and a eukaryotic microorganism in a single complex biological sample wherein the cells of such microorganisms are lysed by combining the sample with a lysis solution and contacting the nucleic acid released from the microorganisms with selective nucleic acid probes through hybridization techniques. Further provided are methods which permit the detection of a Gram-positive bacterium with at least one other microorganism selected from the group consisting of yeast, protozoa, mycoplasma and Gram-negative bacteria in a single complex biological sample. In other aspects of the invention, the methods disclosed permit the detection of microorganisms associated with vaginal disorders.
    Type: Grant
    Filed: October 8, 1993
    Date of Patent: December 23, 1997
    Assignee: Becton Dickinson and Company
    Inventors: Diana K. Sheiness, Trevor H. Adams, Michael R. Stamm, Gerard A. Cangelosi, Theresa B. Britschgi, Connie K. Dix
  • Quantification of bacteria using a nucleic acid hybridization assay
    Patent number: 5334501
    Abstract: This invention provides for a method of quantifying bacteria using a bacterial specific nucleic acid probe which is complementary to a unique and highly conserved region of the 16S ribosomal RNA (rRNA) of bacteria. This probe permits the rapid detection of 16S rRNA in a sample and by comparison with known standards, one can estimate the total bacterial count in the sample. The method is accurate and reproducible and conducted at temperatures of between about 120.degree. to about 40.degree. C.
    Type: Grant
    Filed: April 1, 1993
    Date of Patent: August 2, 1994
    Assignee: Microprobe Corporation
    Inventors: Trevor H. Adams, Dennis E. Schwartz, Nicolaas M. J. Vermuelen, Roy H. Kanemoto