Patents by Inventor Trevor J. Knott

Trevor J. Knott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spheroid formulation
    Patent number: 5622722
    Abstract: A pharmaceutical composition comprising spheroids comprising a water-soluble active ingredient or a pharmaceutically acceptable salt thereof, microcrystalline cellulose and a sugar. Preferably the active ingredient is hydromorphone hydrochloride and the sugar is lactose. Surprisingly the incorporation of a sugar improves the dissolution rate of the spheroid formulation instead of reducing the dissolution rate by competing with the active ingredient for solubilization.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: April 22, 1997
    Assignee: Euro-Celtique, S.A.
    Inventors: Trevor J. Knott, Sandra T. A. Malkowska, Philip J. Neale, Stewart T. Leslie, Ronald B. Miller, Derek A. Prater