Patents by Inventor Trevor John Grinter

Trevor John Grinter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrochloride salt of an azabicyclo[3.2.1]octane derivative
    Patent number: 8263611
    Abstract: The invention relates to a hydrochloride salt of (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-[(methyloxy)methyl]-8-azabicyclo[3.2.1]octane, uses of the salt as a medicament in the treatment inter alia of disorders of the central nervous system and pharmaceutical compositions and dosage forms comprising the salt.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: September 11, 2012
    Assignee: Neurosearch A/S
    Inventors: Trevor John Grinter, Peter Moldt, Frank Watjen
  • HYDROCHLORIDE SALT OF AN AZABICYCLO[3.2.1]OCTANE DERIVATIVE
    Publication number: 20100056561
    Abstract: The invention relates to a hydrochloride salt of (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-[(methyloxy)methyl]-8-azabicyclo[3.2.1]octane, uses of the salt as a medicament in the treatment inter alia of disorders of the central nervous system and pharmaceutical compositions and dosage forms comprising the salt.
    Type: Application
    Filed: February 28, 2008
    Publication date: March 4, 2010
    Applicant: NeuroSearch A/S
    Inventors: Trevor John Grinter, Peter Moldt, Frank Watjen
  • Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one and/or 4-aminomethylene-pyrrolidin-3-alkoxyimino derivatives and/or gemifloxacin or a salt thereof
    Patent number: 7199242
    Abstract: The invention provides a process for the production of a compound of formula (I): wherein P1 and P2, which may be the same or different, are amino protecting groups, which comprises protection of a compound of formula (II) in solution phase continuous operation mode. This confers advantages over batch mode operation. The process is usually conducted in reaction equipment adapted for use in continuous processing mode, for example comprising one or more static mixers or a plug flow reactor. Preferably, the plug flow reactor comprises a jacketed tubular reactor fitted inside with internal mixing elements which continually split and remix the reaction streams promoting mass and heat transfer, whereby a uniform plug flow profile with turbulent fluid flow is achieved. The invention also provides a process for production of the antibacterial compound gemifloxacin or a pharmaceutically acceptable salt and/or hydrate thereof, comprising converting a compound of formula (I).
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: April 3, 2007
    Assignee: LG Life Sciences Limited
    Inventors: Clemens Michael Helmut Brechtelsbauer, Stephen Thomas Carpenter, Trevor John Grinter, Michael Anthony Harris, Yeongdae Kim, Youngwoon Kwon, Dongchul Lee, François Xavier Ricard, Richard Neville Saunders
  • Process for the preparation of diphosphonate derivatives
    Patent number: 6048995
    Abstract: A process for the preparation of a compound of formula I, ##STR1## wherein R.sup.1 and R.sup.2 are independently C.sub.1-6 alkyl, R.sup.3 is hydroxy and R.sup.4 and R.sup.5 are independently C.sub.1-6 alkyl is disclosed. The process comprises reacting a compound of formula II, ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are defined as in formula I and X is a leaving group, with a compound of formula III, ##STR3## wherein R.sup.4 and R.sup.5 are independently C.sub.1-6 alkyl, in the presence of a base.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: April 11, 2000
    Inventors: Trevor John Grinter, John David Hayler, Alan Negus, Michael Anthony Harris
  • Process for preparing benzopyran compounds
    Patent number: 5777128
    Abstract: The present invention relates to a process for preparing compounds of structure (I), and the intermediate compound of formula (II).
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: July 7, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John David Hayler, Trevor John Grinter, Vance Novak, Norman John Lewis