Patents by Inventor Trevor M. Penning

Trevor M. Penning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-steroidal suicide substrates of hydroxysteroid dehydrogenase
    Patent number: 5118621
    Abstract: Compounds, such as 1-(4'-nitrophenyl)-2-propen-1-ol, are disclosed which are highly selective non-steroidal suicide substrates for rat liver 3.alpha.-hydroxysteroid dehydrogenase.
    Type: Grant
    Filed: June 18, 1990
    Date of Patent: June 2, 1992
    Assignee: University of Pennsylvania
    Inventors: Trevor M. Penning, Joseph W. Ricigliano
  • Irreversible ligands for nonsteroidal antiinflammatory drug and prostaglandin binding sites
    Patent number: 5068250
    Abstract: Compounds such as 1-(4-bromoacetamidobenzyl)-5-methoxy-2-methylindole-3-acetic acid, N-(4-bromoacetamidophenyl) anthranilic acid and N-(3-bromoacetamidophenyl) anthranilic acid function as irreversible ligands for nonsteroidal antiinflammatory drug (NSAID) and prostaglandin binding sites. It is therefore expected that these compounds, and analogs thereof, will have utility as anti-inflammatory drugs, as affinity labeling agents and as ligands for use in affinity chromatography.
    Type: Grant
    Filed: September 29, 1988
    Date of Patent: November 26, 1991
    Assignee: Trustees of University of Pennsylvania
    Inventors: Trevor M. Penning, Leslie J. Askonas