Patents by Inventor Triantafyllos Chavakis

Triantafyllos Chavakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING PERIODONTAL INFLAMMATION AND PERIODONTAL BONE LOSS
    Publication number: 20140302027
    Abstract: Methods and compositions for use in treating periodontitis include a Del-1 polypeptide.
    Type: Application
    Filed: September 26, 2012
    Publication date: October 9, 2014
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: George Hajishengallis, Triantafyllos Chavakis
  • Inhibition of adhesion and migration of an endothelial cell to fibronectin by neutrophil alpha-defensins
    Patent number: 7576060
    Abstract: The present invention relates to the inhibition of angiogenesis by neutrophil alpha-defensins. Further, the present invention relates to methods involving the inhibition of endothelial cell adhesion to the extracellular matrix, endothelial cell apoptosis, and endothelial cell angiogenesis.mediated by alpha-defensins.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: August 18, 2009
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Douglas Cines, Khalil Bdeir, Triantafyllos Chavakis, Klaus T. Preissner
  • USE OF A COMPOSITION
    Publication number: 20080234189
    Abstract: A method of treatment of a mammal suffering from an inflammatory condition or a cancer includes administering an anti-inflammatory protein or a peptide fraction of the protein having at least one repeating unit, the protein being selected from a group of proteins designated Eap (Extracellular adherence protein). The inflammatory condition may be a non-bacterial or bacterial inflammation.
    Type: Application
    Filed: October 1, 2007
    Publication date: September 25, 2008
    Inventors: Jan-Ingmar FLOCK, Triantafyllos Chavakis, Mathias Herrmann, Klaus T. Preissner
  • Inhibition of angiogenesis by neutrophil alpha-defensins
    Publication number: 20060074020
    Abstract: The present invention relates to the inhibition of angiogenesis by neutrophil alpha-defensins. Further, the present invention relates to methods involving the inhibition of endothelial cell adhesion to the extracellular matrix, endothelial cell apoptosis, and endothelial cell angiogenesis.mediated by alpha-defensins. b) instructions for the use of said ?-defensin for the purpose of modulating a biological process associated with said endothelial cell.
    Type: Application
    Filed: July 20, 2005
    Publication date: April 6, 2006
    Inventors: Douglas Cines, Khalil Bdeir, Triantafyllos Chavakis, Klaus Preissner
  • Medicament against thrombotic diseases
    Publication number: 20050058636
    Abstract: Medicaments against thrombotic diseases are described which contain as an active ingredient the domain-5 of high molecular weight kininogen or a domain-5-peptide of the carboxy-terminal region of the high molecular weight kininogen. They are useful as thrombolytic or fibrinolytic agents or as agents against platelet aggregation as well as prophylactic agents against thromboembolic complication.
    Type: Application
    Filed: March 14, 2003
    Publication date: March 17, 2005
    Inventors: Klaus Preissner, Triantafyllos Chavakis
  • Use of a composition
    Publication number: 20030105020
    Abstract: A method of treatment of a mammal suffering from an inflammatory condition by administration of an anti-inflammatory drug comprising a protein or a peptide fraction of said protein comprising at least one repeating unit thereof, said protein being selected from a group of proteins designated Eap (Extracellular adherence protein). The inflammatory condition may be a non-bacterial or bacterial inflammation.
    Type: Application
    Filed: November 18, 2002
    Publication date: June 5, 2003
    Inventors: Jan-Ingmar Flock, Triantafyllos Chavakis, Mathias Herrmann, Klaus T. Preissner