Abstract: The managed distribution solution (“MDS”) of the present invention includes systems and methods for giving the point-of-service provider (“POS”) (i.e., physicians, home infusion, clinics, long term care, etc.) an alternative to the traditional buy and bill model. In one exemplary embodiment in accordance with the present invention, a processing site is configured for communicating with a distributor, a Client and a POS to facilitate delivery of a Product from a distributor to the POS. In another exemplary embodiment of the present invention, a billing system is associated with the processing site for facilitating billing for Products delivered to POS to a Client, when a patient of the Client receives the Product from the POS.