Patents by Inventor Trine Jepsen

Trine Jepsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABILIZED EXENDIN-4 COMPOUNDS
    Publication number: 20090208565
    Abstract: The present invention discloses compositions comprising a stabilized Exendin-4 (1-39) and related compounds. The invention describes stabilized Exendin-4 agonists that include at least one modified amino acid residue particularly at positions Gln13, Met14, Trp25, or Asn28 of the Exendin-4 (1-39) molecule. Disclosed are preferred modifications of deaminated, hydrolyzed, oxidized, or isomerized reaction products of the specified amino acid residues corresponding to the same positions in the Exendin-4 (1-39) molecule. The invention also relates to methods of making and using the stabilized Exendin compounds, such as for the treatment of diabetes.
    Type: Application
    Filed: May 4, 2009
    Publication date: August 20, 2009
    Applicant: Zealand Pharma A/S
    Inventors: Kirsten Ebbehoj, Trine Jepsen, Carsten Boye Knudsen, Bjarne Due Larsen, David Knott
  • Stabilized Exendin-4 compounds
    Patent number: 7544657
    Abstract: The present invention disclosed compositions comprising a stabilized Exendin-4 (1-39) and related compounds. The invention describes stabilized Exendin-4 agonists that include at least one modified amino acid residue particularly at positions Gln 13, Met14, Trp25, or Asn28 of the Exendin-4 (1-39) molecule. Disclosed are preferred modifications of deaminated, hydrolyzed, oxidized, or isomerized reaction products of the specified amino acid residues corresponding to the same positions in the Exendin-4 molecule. The invention also relates to methods of making and using the stabilized Exendin compounds, such as for the treatment of diabetes.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: June 9, 2009
    Assignee: Zealand Pharma A/S
    Inventors: Kirsten Ebbehøj, Trine Jepsen, Carsten Boye Knudsen, Bjarne Due Larsen, David Knott
  • Stabilized exendin-4 compounds
    Publication number: 20060194719
    Abstract: The present invention disclosed compositions comprising a stabilized Exendin-4 (1-39) and related compounds. The invention describes stabilized Exendin-4 agonists that include at least one modified amino acid residue particularly at positions Gln 13, Met14, Trp25, or Asn28 of the Exendin-4 (1-39) molecule. Disclosed are preferred modifications of deaminated, hydrolyzed, oxidized, or isomerized reaction products of the specified amino acid residues corresponding to the same positions in the Exendin-4 molecule. The invention also relates to methods of making and using the stabilized Exendin compounds, such as for the treatment of diabetes.
    Type: Application
    Filed: October 2, 2003
    Publication date: August 31, 2006
    Applicant: Zealand Pharma A/S
    Inventors: Kirsten Ebbehoj, Trine Jepsen, Carsten Knudsen, Bjarne Larsen, David Knott