Abstract: Multiple mode, multiple waveband detector systems and methods are provided. A first window selection signal is received. Based on the first window selection signal, a first read-out pixel window comprising a first subset of pixels of a plurality of pixels of a detector array is determined. A plurality of first image portions of a scene are generated over a first period of time by iteratively, for each iteration of a plurality of iterations over the first period of time, integrating photons on the detector array, reading out only the first subset of pixels in the first read-out pixel window, and storing a first image portion of the scene of the plurality of first image portions of the scene based on the read-out of the first subset of pixels.