Patents by Inventor Tristan Handels

Tristan Handels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10434071
    Abstract: The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 8, 2019
    Assignee: DSM IP ASSETS, B.V.
    Inventors: George Mihov, Guy Draaisma, Silvana Rensina Antonnietta Di Silvestre, Tristan Handels
  • Publication number: 20170367992
    Abstract: The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 28, 2017
    Inventors: George MIHOV, Guy DRAAISMA, Silvana Rensina Antonnietta DI SILVESTRE, Tristan HANDELS
  • Publication number: 20100291116
    Abstract: Microparticle comprising a cross-linked polymer comprising (a) a cross-linker comprising two or more radically polymerizable groups, preferably selected from the group consisting of alkenes, sulfhydryl (SH), thioic, unsaturated esters, unsaturated urethanes, unsaturated ethers, and unsaturated amides; (b) a monofunctional reactive diluent comprising maximum one unsaturated C—C bond represented by the formula R0—C(R1)?CHR2 Formula (I) wherein —R0 is chosen depending on the structure of a selected active agent (c) to be loaded into the microparticle and is chosen to have a structure that when combined with the other components of the microparticle provides a higher affinity of the selected active agent (c) for the microparticle; —each R1 is chosen from hydrogen and substituted and unsubstituted, aliphatic, cycloaliphatic and aromatic hydrocarbon groups which groups optionally contain one or more moieties selected from the group of ester moieties, ether moieties, thioester moieties, thioether moieties, carbamate
    Type: Application
    Filed: September 26, 2008
    Publication date: November 18, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Aylvin Jorge Angelo Athanasius Dias, Bartholomeus Johannes Margretha Plum, Audrey Petit, Tristan Handels