Patents by Inventor Tristan Wilkins
Tristan Wilkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240132830Abstract: A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site. The method also includes combining the concentrated processing solution with a biopolymer containing solution produced in a bioreactor at a second site different from the first site. In some embodiments, the processing solution is a buffer for processing products of cells cultured in a bioreactor. A system and a pharmaceutical production facility for carrying out the method is also provided.Type: ApplicationFiled: December 13, 2023Publication date: April 25, 2024Inventor: Tristan WILKINS
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Patent number: 11965152Abstract: The monitoring and control of bioprocesses is provided. More particularly, the present disclosure is directed to formulating buffer products from multiple buffer solutions for feeding the different operations occurring within a bioprocess line. As the buffer product is being formulated, the buffer product is tested for conductivity, refractive index, and optionally pH. The conductivity measurements are used in conjunction with refractive index measurements to ensure that the buffer product not only has the correct concentration of ions but also has the correct concentration of components. A controller can be used to make automatic adjustments to the buffer product should any of the measured parameters fall outside a preset range.Type: GrantFiled: February 6, 2020Date of Patent: April 23, 2024Assignee: Lonza Ltd.Inventors: Thaddaeus Webster, Carrie Mason, Tristan Wilkins
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Patent number: 11898137Abstract: A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site. The method also includes combining the concentrated processing solution with a biopolymer containing solution produced in a bioreactor at a second site different from the first site. In some embodiments, the processing solution is a buffer for processing products of cells cultured in a bioreactor. A system and a pharmaceutical production facility for carrying out the method is also provided.Type: GrantFiled: May 18, 2020Date of Patent: February 13, 2024Assignee: LONZA LTDInventor: Tristan Wilkins
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Patent number: 11859403Abstract: A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.Type: GrantFiled: May 27, 2022Date of Patent: January 2, 2024Assignee: LONZA LTDInventors: Leander Biffiger, Sandra Carbonneau, Andre Collioud, Jonathan Fortin, Dominique Imboden, Torsten Schmidt, Stefan Stoffel, Diego Studer, Christoph Vogel, Stefan Widmer, Tristan Wilkins, Lesley Wood, Alexander Zahiri
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Publication number: 20220290456Abstract: A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.Type: ApplicationFiled: May 27, 2022Publication date: September 15, 2022Inventors: Leander BIFFIGER, Sandra CARBONNEAU, Andre COLLIOUD, Jonathan FORTIN, Dominik IMBOLDEN, Torsten SCHMIDT, Stefan STOFFEL, Diego STUDER, Christoph VOGEL, Stefan WIDMER, Tristan WILKINS, Lesley WOOD, Alexander ZAHIRI
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Patent number: 11377865Abstract: A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.Type: GrantFiled: May 26, 2020Date of Patent: July 5, 2022Assignee: LONZA LTDInventors: Leander Biffiger, Sandra Carbonneau, Andre Collioud, Jonathan Fortin, Dominik Imbolden, Torsten Schmidt, Stefan Stoffel, Diego Studer, Christoph Vogel, Stefan Widmer, Tristan Wilkins, Lesley Wood, Alexander Zahiri
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Publication number: 20200291670Abstract: A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.Type: ApplicationFiled: May 26, 2020Publication date: September 17, 2020Inventors: Leander BIFFIGER, Sandra CARBONNEAU, Andre COLLIOUD, Jonathan FORTIN, Dominik IMBOLDEN, Torsten SCHMIDT, Stefan STOFFEL, Diego STUDER, Christoph VOGEL, Stefan WIDMER, Tristan WILKINS, Lesley WOOD, Alexander ZAHIRI
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Publication number: 20200283718Abstract: A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site. The method also includes combining the concentrated processing solution with a biopolymer containing solution produced in a bioreactor at a second site different from the first site. In some embodiments, the processing solution is a buffer for processing products of cells cultured in a bioreactor. A system and a pharmaceutical production facility for carrying out the method is also provided.Type: ApplicationFiled: May 18, 2020Publication date: September 10, 2020Inventor: Tristan WILKINS
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Publication number: 20200255792Abstract: The monitoring and control of bioprocesses is provided. More particularly, the present disclosure is directed to formulating buffer products from multiple buffer solutions for feeding the different operations occurring within a bioprocess line. As the buffer product is being formulated, the buffer product is tested for conductivity, refractive index, and optionally pH. The conductivity measurements are used in conjunction with refractive index measurements to ensure that the buffer product not only has the correct concentration of ions but also has the correct concentration of components. A controller can be used to make automatic adjustments to the buffer product should any of the measured parameters fall outside a preset range.Type: ApplicationFiled: February 6, 2020Publication date: August 13, 2020Inventors: Thaddaeus Webster, Carrie Mason, Tristan Wilkins
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Patent number: 10689873Abstract: A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.Type: GrantFiled: July 25, 2017Date of Patent: June 23, 2020Assignee: LONZA LTDInventors: Leander Biffiger, Sandra Carbonneau, Andre Collioud, Jonathan Fortin, Dominik Imbolden, Torsten Schmidt, Stefan Stoffel, Diego Studer, Christoph Vogel, Stefan Widmer, Tristan Wilkins, Lesley Wood, Alexander Zahiri
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Patent number: 10669518Abstract: A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site. The method also includes combining the concentrated processing solution with a biopolymer containing solution produced in a bioreactor at a second site different from the first site. In some embodiments, the processing solution is a buffer for processing products of cells cultured in a bioreactor. A system and a pharmaceutical production facility for carrying out the method is also provided.Type: GrantFiled: August 2, 2017Date of Patent: June 2, 2020Assignee: LONZA LTDInventor: Tristan Wilkins
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Publication number: 20190367858Abstract: The present disclosure is directed to the organic growth and phasing design for a system for the industrial growth of biologics. A system may include a number of subsystems, such as a buffer distribution subsystem, a media preparation subsystem, a bioreactor subsystem, a harvest subsystem, and/or a purification subsystem. The subsystems may be highly interconnected for flexible process flow design. Additionally, the subsystems may be constructed with a total output capacity with a total number of equipment stations and operated at a lower output capacity with fewer than the total equipment stations to maintain headroom for growth in phases.Type: ApplicationFiled: May 10, 2019Publication date: December 5, 2019Inventors: John Gunst, Jonathan Fortin, Tristan Wilkins
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Publication number: 20180037861Abstract: A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site. The method also includes combining the concentrated processing solution with a biopolymer containing solution produced in a bioreactor at a second site different from the first site. In some embodiments, the processing solution is a buffer for processing products of cells cultured in a bioreactor. A system and a pharmaceutical production facility for carrying out the method is also provided.Type: ApplicationFiled: August 2, 2017Publication date: February 8, 2018Inventor: Tristan Wilkins
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Publication number: 20170321443Abstract: A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.Type: ApplicationFiled: July 25, 2017Publication date: November 9, 2017Inventors: Leander Biffiger, Sandra Carbonneau, Andre Collioud, Jonathan Fortin, Dominik Imbolden, Torsten Schmidt, Stefan Stoffel, Diego Studer, Christoph Vogel, Stefan Widmer, Tristan Wilkins, Lesley Wood, Alexander Zahiri