Patents by Inventor Trixi Brandl

Trixi Brandl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THIAZOLYL-DIHYDRO-CHINAZOLINE
    Publication number: 20090131424
    Abstract: Disclosed are compounds of general formula (I), wherein the groups A, R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-quinazolines and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: January 9, 2009
    Publication date: May 21, 2009
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Trixi BRANDL, Udo MAIER, Christoph HOENKE, Anne T. JOERGENSEN, Alexander PAUTSCH, Steffen BREITFELDER, Matthias GRAUERT, Matthias HOFFMANN, Stefan SCHEUERER, Klaus ERB, Michael PIEPER, Ingo PRAGST
  • Thiazolyl-dihydro-cyclopentapyrazole
    Patent number: 7517995
    Abstract: Disclosed are compounds of general formula (I), wherein the groups R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-cyclopentapyrazoles and the use thereof as pharmaceutical compositions.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: April 14, 2009
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Steffen Breitfelder, Udo Maier, Christoph Hoenke, Anne T. Joergensen, Alexander Pautsch, Trixi Brandl, Matthias Grauert, Matthias Hoffmann, Stefan Scheuerer, Klaus Erb, Michael Pieper, Ingo Pragst
  • THIAZOLYL-DIHYDRO-INDAZOLE
    Publication number: 20090093474
    Abstract: The present invention relates to new thiazolyl-dihydro-indazoles of general formula (I) wherein the groups R1, R2 and R3 have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-indazoles and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: November 25, 2008
    Publication date: April 9, 2009
    Inventors: Matthias Grauert, Udo Maier, Matthias Hoffmann, Stefan Scheuerer, Anne T. Joergensen, Alexander Pautsch, Trixi Brandl, Christoph Hoenke, Steffen Breitfelder, Klaus Erb, Michael Pieper, Ingo Pragst
  • MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES
    Publication number: 20090048267
    Abstract: The present invention relates to the use of indolinones of general formula substituted in the 6 position, wherein R1, to R5 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.
    Type: Application
    Filed: May 12, 2008
    Publication date: February 19, 2009
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: John Edward PARK, Nveed Chaudhary, Thorsten Lehmann-Lintz, Armin Heckel, Gerald Juergen Roth, Joerg Kley, Trixi Brandl, Georg Dahmann, Matthias Grauert
  • Piperazinyl Compounds
    Publication number: 20080293944
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: May 30, 2008
    Publication date: November 27, 2008
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Steffen Breitfelder, Christian Eickmeier, Martin Steegmaier, Gisela Schnapp, Anke Baum, Jens Juergen Quant, Flavio Solca, Florian Colbatzky
  • Intermediate Compounds for making Dihydropteridinones Useful as Pharmaceutical Compositions
    Publication number: 20080171747
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: November 16, 2007
    Publication date: July 17, 2008
    Inventors: Matthias Hoffman, Matthias Grauert, Trixi Brandl, Steffen Breitfelder, Christian Eickmeier, Martin Steegmaier, Gisela Schnapp, Anke Baum, Jens Juergen Quant, Flavio Solca, Florian Colbatzky
  • Organic Compounds and Their Uses
    Publication number: 20080045530
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: April 9, 2007
    Publication date: February 21, 2008
    Inventors: Trixi Brandl, Shawn Britt, Sylvain Cottens, Claus Ehrhardt, Jiping Fu, Subramanian Karur, Hongju Li, Peichao Lu, David Parker, Michael Patane, Branko Radetich, Prakash Raman, Stefan Randl, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Ritesh Tichkule, Yanyi Zhu
  • Organic Compounds and Their Uses
    Publication number: 20070286842
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: April 9, 2007
    Publication date: December 13, 2007
    Inventors: Trixi Brandl, Jiping Fu, Francois Lenoir, David Parker, Michael Patane, Branko Redetich, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Aregahegn Yifru, Rui Zheng
  • THIAZOLYL-DIHYDRO-INDAZOLE
    Publication number: 20070259855
    Abstract: Disclosed are compounds of general formula (I), wherein the groups R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-indazoles and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: November 8, 2007
    Inventors: Udo Maier, Matthias Grauert, Matthias Hoffmann, Christoph Hoenke, Anne Joergensen, Alexander Pautsch, Trixi Brandl, Steffen Breitfelder, Stefan Scheuerer, Klaus Erb, Michael Pieper, Ingo Pragst
  • THIAZOLYL-DIHYDRO-QUINAZOLINE
    Publication number: 20070244104
    Abstract: Disclosed are thiazolyl-dihydro-quinazolines of general formula (I) wherein the groups R1 to R4 have the meanings given in the claims and specification, the isomers thereof, and processes for preparing these compounds and their use as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 18, 2007
    Inventors: Trixi Brandl, Udo Maier, Matthias Hoffmann, Stefan Scheuerer, Anne Joergensen, Alexander Pautsch, Steffen Breitfelder, Matthias Grauert, Christoph Hoenke, Klaus Erb, Michael Pieper, Ingo Pragst
  • THIAZOLYL-DIHYDRO-CHINAZOLINE
    Publication number: 20070238746
    Abstract: Disclosed are compounds of general formula (I), wherein the groups A, R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-quinazolines and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 11, 2007
    Inventors: Trixi Brandl, Udo Maier, Christoph Hoenke, Anne Joergensen, Alexander Pautsch, Steffen Breitfelder, Matthias Grauert, Matthias Hoffmann, Stefan Scheuerer, Klaus Erb, Michael Pieper, Ingo Pragst
  • THIAZOLYL-DIHYDRO-CYCLOPENTAPYRAZOLE
    Publication number: 20070238730
    Abstract: Disclosed are compounds of general formula (I), wherein the groups R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-cyclopentapyrazoles and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 11, 2007
    Inventors: Steffen Breitfelder, Udo Maier, Christoph Hoenke, Anne Joergensen, Alexander Pautsch, Trixi Brandl, Matthias Grauert, Matthias Hoffmann, Stefan Scheuerer, Klaus Erb, Michael Pieper, Ingo Pragst
  • THIAZOLYL-DIHYDRO-INDAZOLE
    Publication number: 20070238718
    Abstract: The present invention relates to new thiazolyl-dihydro-indazoles of general formula (I) wherein the groups R1, R2 and R3 have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-indazoles and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 11, 2007
    Inventors: Matthias GRAUERT, Udo Maier, Matthias Hoffmann, Stefan Scheuerer, Anne Joergensen, Alexander Pautsch, Trixi Brandl, Christoph Hoenke, Steffen Breitfelder, Klaus Erb, Michael Pieper, Ingo Pragst
  • Medicaments for the Treatment or Prevention of Fibrotic Diseases
    Publication number: 20060154939
    Abstract: The present invention relates to the use of indolinones of general formula substituted in the 6 position, wherein R1 to R5 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.
    Type: Application
    Filed: December 20, 2005
    Publication date: July 13, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: John Park, Nveed Chaudhary, Thorsten Lehmann-Lintz, Armin Heckel, Gerald Roth, Joerg Kley, Trixi Brandl, Georg Dahmann, Matthias Grauert
  • Medicaments for the Treatment or Prevention of Fibrotic Diseases
    Publication number: 20060142373
    Abstract: The present invention relates to the use of indolinones of general formula substituted in the 6 position, wherein R1 to R5 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.
    Type: Application
    Filed: December 20, 2005
    Publication date: June 29, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: John Park, Gerald Roth, Armin Heckel, Nveed Chaudhary, Trixi Brandl, Georg Dahmann, Matthias Grauert
  • PI3-kinases
    Publication number: 20060106013
    Abstract: New compounds of formula 1 are provided which by virtue of their pharmaceutical activity as PI3-kinase modulators may be used in the therapeutic field for the treatment of inflammatory or allergic diseases. Examples of these include inflammatory and allergic respiratory complaints, inflammatory diseases of the gastrointestinal tract and motor apparatus, inflammatory and allergic skin diseases, inflammatory eye diseases, diseases of the nasal mucosa, inflammatory or allergic conditions involving autoimmune reactions or inflammations of the kidney.
    Type: Application
    Filed: October 5, 2005
    Publication date: May 18, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Steffen Breitfelder, Udo Maier, Trixi Brandl, Christoph Hoenke, Matthias Grauert, Alexander Pautsch, Matthias Hoffmann, Frank Kalkbrenner, Anne Joergensen, Gerhard Schaenzle, Stefan Peters, Frank Buettner, Eckhart Bauer
  • Thiazolyl-dihydro-indazole
    Publication number: 20060100254
    Abstract: The present invention encompasses compounds of the general formula (1) in which R1 to R3 are defined as in Claim 1, which are suitable for treating diseases which are characterized by excessive or anomalous cell proliferation, and their use for producing a pharmaceutical having the abovementioned properties.
    Type: Application
    Filed: October 5, 2005
    Publication date: May 11, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Bodo Betzemeier, Trixi Brandl, Steffen Breitfelder, Ralph Brueckner, Thomas Gerstberger, Michael Gmachl, Matthias Grauert, Frank Hilberg, Christoph Hoenke, Matthias Hoffmann, Maria Impagnatiello, Dirk Kessler, Christian Klein, Bernd Krist, Udo Maier, Darryl McConnell, Charlotte Reither, Stefan Scheuerer, Andreas Schoop, Norbert Schweifer, Oliver Simon, Martin Steegmaier, Steffen Steurer, Irene Waizenegger, Ulrike Weyer-Czernilofsky, Andreas Zoephel
  • New pyridodihydropyrazinones, process for their manufacture and use thereof as medicaments
    Publication number: 20060009457
    Abstract: Disclosed are pyridodihydropyrazinone compounds, processes for preparing them and their use as pharmaceutical compositions. The compounds according to the invention correspond to general formula (I), while the groups L, R1, R2, R3, R4 and R5 may have the meanings given in the claims and specification.
    Type: Application
    Filed: July 7, 2005
    Publication date: January 12, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Martin Steegmaier, Rudolf Hauptmann
  • Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
    Patent number: 6861422
    Abstract: The present invention relates to new dihydropteridinones of general formula (I): wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: March 1, 2005
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Steffen Breitfelder, Christian Eickmeier, Martin Steegmaier, Gisela Schnapp, Anke Baum, Jens Juergen Quant, Flavio Solca, Florian Colbatzky
  • Methods of treating diseases or conditions using dihydropteridinone compounds
    Publication number: 20050014760
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: July 30, 2004
    Publication date: January 20, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Steffen Breitfelder, Christian Eickmeier, Martin Steegmaier, Gisela Schnapp, Anke Baum, Jens Quant, Flavio Solca, Florian Colbatzky