Patents by Inventor TROND HELGERUD

TROND HELGERUD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID DISPERSIONS
    Publication number: 20230059619
    Abstract: A solid dispersion comprising: (a) a pharmaceutical active ingredient or a nutraceutical active ingredient having a low solubility; and (b) sodium or potassium alginate. In addition, a drug dosage form prepared from such a solid dispersion.
    Type: Application
    Filed: May 31, 2022
    Publication date: February 23, 2023
    Inventors: Jian Guan, Shirui Mao, Trond Helgerud, Yeli Zhang
  • Nanosuspension formulation
    Patent number: 11504324
    Abstract: A nanosuspension comprising (a) a pharmaceutical active ingredient or nutraceutical active ingredient having low solubility; (b) at least one alginate selected from the group consisting of (i) sodium alginate having a viscosity of 100 mPa·s or less in a 1% solution in water at 20° C. and (ii) potassium alginate; and (c) water. Also, a drug dosage form prepared from such a nanosuspension.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: November 22, 2022
    Assignee: DUPONT NUTRITION USA, INC.
    Inventors: Shirui Mao, Jian Guan, Trond Helgerud, Yeli Zhang
  • NANOSUSPENSION FORMULATION
    Publication number: 20180250227
    Abstract: A nanosuspension comprising (a) a pharmaceutical active ingredient or nutraceutical active ingredient having low solubility; (b) at least one alginate selected from the group consisting of (i) sodium alginate having a viscosity of 100 mPa·s or less in a 1% solution in water at 20° C. and (ii) potassium alginate; and (c) water. Also, a drug dosage form prepared from such a nanosuspension.
    Type: Application
    Filed: November 18, 2015
    Publication date: September 6, 2018
    Inventors: Shirui Mao, Jian Guan, Trond Helgerud, Yeli Zhang
  • SOLID DISPERSIONS
    Publication number: 20180042851
    Abstract: A solid dispersion comprising: (a) a pharmaceutical active ingredient or a nutraceutical active ingredient having a low solubility; and (b) sodium or potassium alginate. In addition, a drug dosage form prepared from such a solid dispersion.
    Type: Application
    Filed: March 10, 2016
    Publication date: February 15, 2018
    Inventors: Jian Guan, Shirui Mao, Trond Helgerud, Yeli Zhang
  • GELLING COMPOSITIONS AND METHODS
    Publication number: 20070087038
    Abstract: A method for the administration of a composition that augments the acidity of gastric fluid such that intra-gastric gelation of the polysaccharide:acid soluble multivalent cation formulation is initiated independent of endogenous acid secretion. The composition includes:(a) at least one of a polysaccharide, modified polysaccharide, or polysaccharide salt, each capable of ionotropic gelation, (b) at least one source of multivalent cations capable of solubilization at an acidic pH, and (c) at least one acid component capable of providing a controlled release of protons sufficient to solubilize the multivalent cations. The composition is capable of hydrating in aqueous media and subsequently forming a gel in a stomach when ingested, which gel resists peristaltic forces and remains in the stomach for an extended time.
    Type: Application
    Filed: October 4, 2006
    Publication date: April 19, 2007
    Applicant: FMC BIOPOLYMER AS
    Inventors: JOHNATHAN RICHARDSON, PETER DETTMAR, OLAV GASEROD, TROND HELGERUD