Patents by Inventor Troy E. Wilson

Troy E. Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer derivatives
    Patent number: 9574048
    Abstract: The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorporation of non-genetically encoded amino acids, e.g., those amino acids containing an azide or acetylene moiety, into proteins in response to a selector codon and the subsequent modification of those amino acids with a suitably reactive PEG derivative.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: February 21, 2017
    Assignee: Ambrx, Inc.
    Inventor: Troy E. Wilson
  • Modified human four helical bundle polypeptides and their uses
    Patent number: 9260472
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: February 16, 2016
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. Dimarchi, Anna-Maria A. Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Antigen-binding polypeptides and their uses
    Patent number: 9175083
    Abstract: Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: November 3, 2015
    Assignee: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Troy E. Wilson, Thomas P. Cujec, Feng Tian, Anna-Maria A. Hays, Bruce E. Kimmel, Lillian Ho
  • Modified human four helical bundle polypeptides and their uses
    Patent number: 8907064
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: December 9, 2014
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified human four helical bundle polypeptides and their uses
    Patent number: 8906676
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: December 9, 2014
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Human growth hormone modified at position 35
    Patent number: 8778880
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: July 15, 2014
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified human interferon polypeptides and their uses
    Patent number: 8232371
    Abstract: Modified interferon polypeptides with at least one non-naturally-encoded amino acid and uses thereof are provided.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: July 31, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria A. Hays Putnam, Troy E. Wilson
  • MODIFIED HUMAN INTERFERON POLYPEPTIDES AND THEIR USES
    Publication number: 20120142896
    Abstract: Modified interferon polypeptides with at least one non-naturally-encoded amino acid and uses thereof are provided.
    Type: Application
    Filed: December 8, 2011
    Publication date: June 7, 2012
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Anna-Maria A. HAYS, Troy E. WILSON
  • Modified human growth hormone
    Patent number: 8143216
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: March 27, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria A. Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified human interferon polypeptides and their uses
    Patent number: 8119603
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: February 21, 2012
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria Hays, Troy E. Wilson
  • Modified human interferon polypeptides with at least one non-naturally encoded amino acid and their uses
    Patent number: 8097702
    Abstract: Modified interferon polypeptides with at least one non-naturally-encoded amino acid and uses thereof are provided.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: January 17, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria A. Hays, Troy E. Wilson
  • Modified Human Growth Hormone
    Publication number: 20110294161
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: February 25, 2011
    Publication date: December 1, 2011
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Richard D. DIMARCHI, Anna-Maria HAYS, Troy E. WILSON, Bee-Cheng SIM, David C. LITZINGER
  • Polymer Derivatives
    Publication number: 20110269974
    Abstract: The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorporation of non-genetically encoded amino acids, e.g., those amino acids containing an azide or acetylene moiety, into proteins in response to a selector codon and the subsequent modification of those amino acids with a suitably reactive PEG derivative.
    Type: Application
    Filed: July 14, 2011
    Publication date: November 3, 2011
    Applicant: AMBRX, INC.
    Inventor: Troy E. WILSON
  • Azide- or acetylene-terminated poly(alkylene oxide, oxyethylated polyol or olefinic Alcohol)
    Patent number: 8008428
    Abstract: The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorporation of non-genetically encoded amino acids, e.g., those amino acids containing an azide or acetylene moiety, into proteins in response to a selector codon and the subsequent modification of those amino acids with a suitably reactive PEG derivative.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: August 30, 2011
    Assignee: Ambrx, Inc.
    Inventor: Troy E. Wilson
  • Modified human growth horomone polypeptides and their uses
    Patent number: 7939496
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: May 10, 2011
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Branched acetylene-containing poly(alkylene oxides, oxyethylated polyols or olefinic alcohols)
    Patent number: 7820766
    Abstract: The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorporation of non-genetically encoded amino acids, e.g., those amino acids containing an azide or acetylene moiety, into proteins in response to a selector codon and the subsequent modification of those amino acids with a suitably reactive PEG derivative.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: October 26, 2010
    Assignee: Ambrx, Inc.
    Inventor: Troy E. Wilson
  • Branched Acetylene-Containing Poly(Alkylene Oxides, Oxyethylated Polyols or Olefinic Alcohols)
    Publication number: 20100217050
    Abstract: The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorporation of non-genetically encoded amino acids, e.g., those amino acids containing an azide or acetylene moiety, into proteins in response to a selector codon and the subsequent modification of those amino acids with a suitably reactive PEG derivative.
    Type: Application
    Filed: May 6, 2010
    Publication date: August 26, 2010
    Applicant: AMBRX, INC.
    Inventor: Troy E. WILSON
  • Acetylene group-containing poly(alkylene oxide, oxyethylated polyol or olefinic alcohol)
    Patent number: 7737226
    Abstract: The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorporation of non-genetically encoded amino acids, e.g., those amino acids containing an azide or acetylene moiety, into proteins in response to a selector codon and the subsequent modification of those amino acids with a suitably reactive PEG derivative.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: June 15, 2010
    Assignee: AMBRX, Inc.
    Inventor: Troy E. Wilson
  • Biosynthetic Polypeptides Utilizing Non-Naturally Encoded Amino Acids
    Publication number: 20100048871
    Abstract: Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: November 4, 2009
    Publication date: February 25, 2010
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Anna-Maria HAYS, Troy E. WILSON, David C. LITZINGER, Roberto MARIANI, Bruce E. KIMMEL, William M. KEEFE
  • Biosynthetic polypeptides utilizing non-naturally encoded amino acids
    Patent number: 7638299
    Abstract: Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: December 29, 2009
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria Hays, Troy E. Wilson, David C. Litzinger, Roberto Mariani, Bruce E. Kimmel, William M. Keefe