Abstract: A rotor-hub flap-measurement system includes a rotor hub operable to flap relative to a main-rotor axis, a flap-linkage arm, a first end of the flap-linkage arm rotatably coupled to the rotor hub, the flap-linkage arm responsive to flapping of the rotor hub, and a magneto-resistive sensor system rotatably coupled to a second end of the flap-linkage arm and responsive to movement of the flap-linkage arm.

Abstract: Retractable stairs for mounting in an exterior doorway of a recreational vehicle are provided with a spaced apart stringers and a tread extending between the stringers. Spaced apart straps are connected to upper ends of the stringers and are pivotally mounted to a floor in an interior space of the recreational vehicle to allow movement of the stringers and the tread through the exterior doorway between a retracted position stowed within the recreational vehicle and a deployed position outside of the recreational vehicle. A threshold plate is positioned between the straps and is fixed against movement during the pivoting movement of the straps. Locking latches extend outwardly from the stringers and are positionable for engaging a jamb of the exterior doorway for releasably securing the stringers and the tread in the retracted position. Extensible support legs are mounted on the stringers and extendable downwardly below the stringers to engage a ground surface for supporting the retractable stairs.

Abstract: An electrosurgical wand is disclosed for treating a plurality of tissues at a variety of tissue locations. The electrosurgical wand includes a handle on a proximal end and an elongate shaft with a combination active electrode at the distal end. The combination active electrode includes with a blade and screen portion; the blade portion extending along and laterally from the wand longitudinal axis, forming a dissecting tip. The screen portion extends from the blade portion at an obtuse angle and has at least one aspiration aperture through it. The wand also includes a second and third electrode, proximally spaced from the combination active electrode. The second electrode spans a portion of an outside surface of the wand adjacent the blade portion, while the third electrode spans a portion of the outside surface of the wand opposite the second electrode.

Abstract: Debris filtration and strainer systems for a fluid handling device are provided herein. The strainer systems can include one or more of a strainer basket, a removable insert, and an adapter for removably engaging the removable insert with the strainer basket. The removable insert includes a liner having a plurality of openings that are the same size as, or smaller than, the openings of a the strainer basket, and which is inserted into the strainer basket to capture debris from water passing therethrough, preventing clogging of the strainer basket and reducing the frequency of cleanings of the strainer basket. The liner can be fabricated from a biodegradable material, and thus can be easily removed, disposed of, and replaced. The removable insert can include a rigid connection tab with one or more features for removably engaging the strainer basket and/or an adapter positioned between the strainer basket and the removable insert.

Abstract: An anti-allergenic product having: at least 0.01% w/w of a plant extract, wherein the plant extract is selected from the group consisting of Camellia sinensis leaf extract, Melaleuca alternifolia leaf oil, and mixtures thereof; an amphiphilic preservative, and a glycolipid. The eyelid cleansing composition is configured to relieve redness, discomfort and irritation in and around the eyelid.

Abstract: The present invention relates to compounds of formula (I) as activators of glucagon-like peptide 1 (GLP1) receptor for the treatment of obesity, type 2 diabetes mellitus, insulin resistance, hyperinsulinemia, glucose intolerance, hyperglycemia, one or more diabetic complications, diabetic nephropathy, dyslipidemia, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), hypertension, atherosclerosis, peripheral arterial disease, stroke, cardiomyopathy, atrial fibrillation, heart failure, coronary heart disease and neuropathy. Preferred compounds are e.g. 2-((4-((S)-2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-imidazole derivatives and similar compounds, such as e.g. C-1, C-2, C-3, C-4 and other compounds.

Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.

Abstract: An improved casing cutter apparatus and method of use are provided for cutting one or more casing strings positioned within a subterranean wellbore during the ‘cut-and-cap’ stage of the wellbore abandonment process. In some embodiments, the apparatus may comprise a cutting attachment operably coupled to at least one mobile power source located at or near the surface of the wellbore.

Abstract: A non-irritating topical composition for moisturizing and cleansing the skin includes: a mixture of moisturizers and conditioning agents; a mixture of surfactants; a mixture of anti-irritant agents; and a mixture of hydrating and rejuvenation agents, in an aqueous vehicle. At least one ingredient in each of the ingredient groups consisting of moisturizers and conditioning agents, surfactants, anti-irritant agents, and hydrating and rejuvenation agents is plant-derived. The composition is essentially free from any synthetic additives or by-products. The composition has a pH in the range of 5.0-8.0.

Abstract: A composition for treating dry skin includes therapeutically active concentrations of one or more skin protecting lipids in an oleaginous base. The skin protecting lipids can include a sphingolipid and at least one oil. The composition is intended for application on the skin surrounding the eyes. The composition is configured to form a protective, occlusive layer that can moisturize the skin and reduce inflammation and itching without stinging, burning, or stripping the skin. According to an exemplary embodiment, the composition is formulated as a high viscosity ointment or gel.

Abstract: A topical skin moisturizing composition comprising: (a) one or more phospholipids; (b) a plurality of demulcents; (c) one or more polymeric moisturizing agents; (d) one or more preservatives; (e) one or more vitamins; and (f) an aqueous vehicle. The moisturizing composition can have an osmolality in the range of 80 mOsm/kg to 500 mOsm/kg. The composition is configured for use on the face and, particularly for application on and around the delicate eye area including the eyelids.

Abstract: An in-store execution issue resolution system includes a processor communicatively coupled to a plurality of data sources, the data sources configured to provide data indicative of inventory and sales. The processor configured to, in response to data from at least one of the data sources indicating that one or more predefined conditions has been met, generate an alert requesting user input, in response to failing to receive user input within a predefined period, initiate at least one action to resolve the alert, and following the initiating of the at least one action, one of deactivate the alert, in response to detecting that initiating the at least one action caused the one or more conditions to clear, and maintain the alert in response to detecting that initiating the at least one action failed to cause the one or more conditions to clear.

Abstract: The invention involves forceps having rounded grasping tips. The rounded tips are configured to avoid puncturing an amniotic membrane during insertion over an ocular surface for the treatment of dry eye disease and inflammation of the eyes and to avoid injuring the conjunctiva during removal of an amniotic membrane from the ocular surface. The forceps have grasping tips at its distal end, wherein one of the grasping tips has a notch on its inside surface. The dimensions of the notch are configured to permit an eye doctor to securely and safely grasp a lip of an amniotic membrane insert for better insertion and removal from an ocular surface.

Abstract: The invention involves forceps having rounded grasping tips. The rounded tips are configured to avoid puncturing an amniotic membrane during insertion over an ocular surface for the treatment of dry eye disease and inflammation of the eyes and to avoid injuring the conjunctiva during removal of an amniotic membrane from the ocular surface. The forceps have grasping tips at its distal end, wherein one of the grasping tips has a notch on its inside surface. The dimensions of the notch are configured to permit an eye doctor to securely and safely grasp a lip of an amniotic membrane insert for better insertion and removal from an ocular surface.

Abstract: A first ocular treatment kit comprises one or more sealed wrappers containing an applicator and a first ocular composition. The applicator includes a shaft and a swab, wherein the swab is coupled to a first end of the shaft. The swab is saturated with the first ocular composition inside the wrapper. The first ocular composition comprises polyaminopropyl biguanide, 1,2 hexanediol and caprylyl glycol. A second ocular treatment kit comprises a first sealed wrapper and a second sealed wrapper. The first sealed wrapper contains an applicator while the second sealed wrapper contains a second ocular composition. The second ocular composition comprises tea tree oil, tea tree oil, sea buckthorn oil and a medium chain triglyceride.

Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.

Abstract: An anti-allergenic product consists of: (A) a substrate; and (B) an eyelid cleansing composition comprising: at least 0.01% w/w of a plant extract, wherein the plant extract is selected from the group consisting of Camellia sinensis leaf extract, Melaleuca alternifolia leaf oil, and mixtures thereof; and phytosphingosine hydrochloride. The substrate can be pre-moistened with the composition. The eyelid cleansing composition is configured to relieve redness, discomfort and irritation in and around the eyelid.

Abstract: Compositions and methods for treating skin redness. According to an embodiment, the invention is a topical skin care composition having a dermatologically acceptable vehicle, such as, water and a plurality of ingredients dissolved in the vehicle. The ingredients include: a blend of natural oils; a plurality of vitamins; and 0.1-1 wt % salicyloyl phytosphingosine. The composition is unsuitable for application on the eyelids or eye area. The blend of natural oils includes: Aloe barbadensis leaf juice extract; Cocos nucifera (coconut oil); hydrolyzed glycosaminoglycans; and caprylic/capric triglycerides. The plurality of vitamins is selected from a group consisting of vitamin C, vitamin E, salts/derivatives of vitamin C and vitamin E, and mixtures thereof. In one aspect, the plurality of vitamins includes: sodium ascorbyl phosphate; disodium lauriminodipropionate tocopheryl phosphate; and jojoba oil.

Abstract: Systems, methods, and kits useful for cleansing the eyelids and maintaining eyelid hygiene are disclosed. In one embodiment, a system for treating or cleansing an ocular region is disclosed. The system consists essentially of: (A) a tubular applicator, wherein the applicator comprises: (i) a first chamber and a second chamber; and (ii) a sealable element situated between the first chamber and the second chamber, wherein at least the second chamber is substantially pre-filled with an ocular composition, and (B) a dispenser, wherein the dispenser is bonded to an external surface of a first end of the applicator.

Abstract: An anti-allergenic composition comprising from about 0.01% to about 50% by weight of a polyphenol, from about 0.01% to about 50% by weight of a terpene compound, and from about 0.001% to about 10% by weight of a glycolipid. The polyphenol has a flavanol derivative. The terpene compound can be selected from the group consisting of a terpene, terpinene, a terpene derivative and combinations thereof. In an embodiment, the sphingolipid comprises about 0.2% phytosphingosine.