Patents by Inventor Trunetta Jo Dockter Ross

Trunetta Jo Dockter Ross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer therapy using beta glucan and antibodies
    Patent number: 8883760
    Abstract: The present invention relates to methods of using neutral soluble glucan and monoclonal antibodies for antitumor therapy. Neutral soluble Beta (1,3; 1,6) glucan (NSG) enhances the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. The glucan does not stimulate the induction of inflammatory cytokines. Also described are methods of using whole glucan particles (WGP) as an immunomodulator by inducing a shift from a Th2 response to the Th1 response, leading to an enhanced antitumor cytotoxic T-cell response.
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: November 11, 2014
    Assignee: University of Louisville Research Foundation, Inc.
    Inventor: Trunetta Jo Dockter Ross
  • Methods of using beta glucan as a radioprotective agent
    Patent number: 8563531
    Abstract: The invention relates to methods for treating and preventing radiation and/or chemotherapy related injury and/or afflictions, such as myelosuppression and decreased macrophage activity, by administering a prophylactically or therapeutically effective amount of particulate, bioavailable ?(1,3; 1,6) glucan. The invention also relates to methods in which ?(1,3; 1,6) glucan is provided in the form of whole glucan particles, microparticulate ?-glucan particles or a combination thereof.
    Type: Grant
    Filed: July 8, 2008
    Date of Patent: October 22, 2013
    Assignees: Biothera, Inc., University of Louisville Research Foundation, Inc.
    Inventors: Gary R. Ostroff, Trunetta Jo Dockter Ross
  • CANCER THERAPY USING WHOLE GLUCAN PARTICLES AND ANTIBODIES
    Publication number: 20100166751
    Abstract: The present invention relates to methods of using whole glucan particles and complement activating antibodies for antitumor therapy. Whole glucan particles enhance the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. This binding enhances innate immune system cytotoxicity, as well as stimulating the release of activating cytokines.
    Type: Application
    Filed: November 9, 2009
    Publication date: July 1, 2010
    Applicants: Biopolymer Engineering (d/b/a Biothera), University of Louisville Research Foundation, Inc.
    Inventors: Gary R. Ostroff, Gordon D. Ross, Trunetta Jo Dockter Ross
  • Whole glucan particles in combination with antibiotics, vaccines and viral monoclonal antibodies
    Publication number: 20090169557
    Abstract: The present invention relates to compositions and methods of using whole glucan particles and agents. Whole glucan particles enhance the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. This binding enhances innate immune system cytotoxicity, as well as stimulating the release of activating cytokines and enhances the bodies response to the agent.
    Type: Application
    Filed: May 10, 2005
    Publication date: July 2, 2009
    Inventors: Gordon D. Ross, Trunetta Jo Dockter Ross, Steven J. Karel, Daniel K. Connors, Bill Kournikakis
  • Methods of using beta glucan as a radioprotective agent
    Publication number: 20090163439
    Abstract: The invention relates to methods for treating and preventing radiation and/or chemotherapy related injury and/or afflictions, such as myelosuppression and decreased macrophage activity, by administering a prophylactically or therapeutically effective amount of particulate, bioavailable ?(1,3; 1,6) glucan. The invention also relates to methods in which ?(1,3; 1,6) glucan is provided in the form of whole glucan particles, microparticulate ?-glucan particles or a combination thereof.
    Type: Application
    Filed: July 8, 2008
    Publication date: June 25, 2009
    Applicants: Biopolymer Engineering, University of Louisville Research Foundation, Inc.
    Inventors: Gary R. Ostroff, Gordon D. Ross, Trunetta Jo Dockter Ross